4 research outputs found
Epidermolysis Bullosa Acquisita Mimicking Linear IgA Bullous Disease in a 5-year-old Child
We present a case of a 5-year-old child with epidermolysis
bullosa acquisita, clinically resembling linear IgA bullous disease.
The case demonstrates that autoimmune bullous dermatoses in childhood
may show a clinical overlap, which makes the diagnosis based
on clinical features highly unreliable. Specific immunofluorescence and
immunoserological tests are crucial for precise diagnosis – in our case
circulating antibodies against collagen VII were detected using ELISA
and indirect immunofluorescence on transfected cells. The disease was
treated with systemic and topical steroids with excellent results