315 research outputs found

    Disused Religious Space: Youth Participation in Built Heritage Regeneration

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    The rights of young people to participate in decision-making processes that affect their lives has been encouraged since the United Nations Convention on the Rights of the Child (1989). Since then, policy-makers and planners have started to consider the views of youth, especially those aged 11–17. The size of the youth population and their feelings of social isolation are two important reasons to include them in the decision-making that affects their local built environment. Little is known about youth opinions of the built environment and in particular disused religious buildings which can become a significant part of local cultural heritage. This paper explores youth perceptions, place attachment and influence on identity of a prominent disused local Methodist church in the City of Belfast. The paper details the expressive methodological approach designed to encourage youth participation in the regeneration scheme. The findings of the study showcase the valuable connections that can be made between youth and heritage religious buildings through education programmes. The project conclusions also highlight the benefits to be gained from engaging youth in local built heritage and will be of interest to those involved in the design, planning and redevelopment processes

    The peptide motif of the single dominantly expressed class I molecule of the chicken MHC can explain the response to a molecular defined vaccine of infectious bursal disease virus (IBDV)

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    In contrast to typical mammals, the chicken MHC (the BF-BL region of the B locus) has strong genetic associations with resistance and susceptibility to infectious pathogens as well as responses to vaccines. We have shown that the chicken MHC encodes a single dominantly expressed class I molecule whose peptide-binding motifs can determine resistance to viral pathogens, such as Rous sarcoma virus and Marek’s disease virus. In this report, we examine the response to a molecular defined vaccine, fp-IBD1, which consists of a fowlpox virus vector carrying the VP2 gene of infectious bursal disease virus (IBDV) fused with ?-galactosidase. We vaccinated parental lines and two backcross families with fp-IBD1, challenged with the virulent IBDV strain F52/70, and measured damage to the bursa. We found that the MHC haplotype B15 from line 15I confers no protection, whereas B2 from line 61 and B12 from line C determine protection, although another locus from line 61 was also important. Using our peptide motifs, we found that many more peptides from VP2 were predicted to bind to the dominantly expressed class I molecule BF2*1201 than BF2*1501. Moreover, most of the peptides predicted to bind BF2*1201 did in fact bind, while none bound BF2*1501. Using peptide vaccination, we identified one B12 peptide that conferred protection to challenge, as assessed by bursal damage and viremia. Thus, we show the strong genetic association of the chicken MHC to a T cell vaccine can be explained by peptide presentation by the single dominantly expressed class I molecule

    Elementary Principals’ Role in Science Instruction

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    This study explores the role elementary school principals play in science education. Specifically, the study employed an online survey of 16 elementary school principals at high-performing campuses in North Texas to explore their perceptions of how they influenced science education on their campuses. The survey used a combination of Likert-type rating scale items and open-ended questions. Responses from elementary principals suggest that the important components of instructional leadership for science included a) collaboration with teachers, b) changing teaching assignments, and c) teacher motivation

    Genome sequence of a gammaherpesvirus from a common bottlenose dolphin (Tursiops truncatus)

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    A herpesvirus genome was sequenced directly from a biopsy specimen of a rectal lesion from a female common bottlenose dolphin. This genome sequence comprises a unique region (161,235 bp) flanked by multiple copies of a terminal repeat (4,431 bp) and contains 72 putative genes. The virus was named common bottlenose dolphin gammaherpesvirus 1

    Research Ethics in Information Systems: Would a Code of Practice Help?

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    The ethical conduct of research is a mark of integrity in the academic and professional worlds. This paper, which draws upon discussions conducted in a panel at the 21st ICIS conference in Brisbane, examines ethical issues associated with three key components of the research process: design, data collection and analysis; writing; and reviewing. The implications of these issues for the IS research community are discussed. Example scenarios are used to illuminate the issues faced by authors and reviewers. After considering the alternatives of strict guidelines enforced by bureaucratic structures, self regulation without guidelines and self regulation through norms set by a code of practice, the last option is recommended because it can lead to better practice in a constructive fashion without either excessive bureaucratic intervention or a free-for-all where anything goes

    Seeking Mind, Body and Spirit Healing—Why Some Men with Prostate Cancer Choose CAM (Complementary and Alternative Medicine) over Conventional Cancer Treatments

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    Little is known about men with prostate cancer who decline conventional treatment and use only complementary and alternative medicine (CAM)

    Decision-making role preferences and information needs: a comparison of colorectal and breast cancer

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    Objective: An exploratory study has been carried out to examine decision-making role preferences and information needs for a sample of people with colorectal cancer (n = 48). The work replicated a larger study carried out for women with breast cancer (n = 150), and this paper compares and contrasts findings for both disease groups. Design: A cross-sectional design was employed, involving structured interviews. The main variables investigated were decision-making preference (using a decisional role preference card sort), perceived decisional role and information need (using an information needs questionnaire). Results: The majority (78%) of the colorectal cancer patients preferred to play a passive role in decision making, in contrast to 52% of women with breast cancer in previous work. Eighty per cent of the colorectal sample and 61% of the women with breast cancer perceived that the doctor had made treatment decisions. Priority information needs for both groups related to cure, spread of disease and treatment options. Conclusions: The two most striking findings from the comparison between the two disease groups relate to the differences in decision-making role preferences and the similarities in information needs. The process of involving people with colorectal cancer in treatment decision making warrants further investigation. The similarity in information needs of the two disease groups has implications for health care professionals providing information to people with cancer

    Evaluating Children’s Advocacy Centers’ Response to Child Sexual Abuse

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    Children’s Advocacy Centers (CACs) play an increasingly significant role in the response to child sexual abuse and other child maltreatment in the United States. First developed in the 1980s, CACs were designed to reduce the stress on child abuse victims and families created by traditional child abuse investigation and prosecution procedures and to improve the effectiveness of the response. According to several experts (Fontana, 1984; Pence and Wilson, 1992; Whitcomb, 1992), child victims were subjected to multiple, redundant interviews about their abuse by different agencies, and were questioned by professionals who had no knowledge of children’s developmental limitations or experience working with children. Child interviews would take place in settings like police stations that would further stress already frightened children. Moreover, the response was hampered because the multiple agencies involved did not coordinate their investigations, and children’s need for services could be neglected
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