939 research outputs found

    Power, Conflict, and Community: Report on a Retrieval Conference, May 1995

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    Also PCMA Working Paper #51.http://deepblue.lib.umich.edu/bitstream/2027.42/51318/1/554.pd

    Analisis Tingkat Implementasi E-government Pada Level Kementerian Indonesia Berdasarkan Framework Deloitte & Touche

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    Saat ini layanan internet telah banyak digunakan untuk berbagai macam keperluan guna meningkatkan efektivitas dan efisiensi penggunanya. Tidak terkecuali pemerintah yang memanfaatkan internet untuk memberikan layanan dan informasi kepada masyarakatnya. Penelitian ini membahas tentang layanan-layanan yang diberikan pemerintah secara online untuk mengetahui sejauh mana penerapan e-government yang dilakukan oleh pemerintah pada level kementerian berdasarkan framework Deloitte & Touche. Ruang lingkup penelitian ini adalah situs kementerian beserta direktoratnya, metode pendekatan yang digunakan untuk memetakan tingkat e-government yaitu framework Deloitte & Touche, serta kategori e-government Government-to-Citizen (G2C) dijadikan sebagai fokus penelitian ini. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif. Hasil dari penelitian ini yaitu implementasi e-government di level kementerian sudah mencapai tingkat kedua, yaitu tahap “official” two-way transactions. Kementerian yang telah mencapai tahap ini antara lain Kementerian Hukum dan HAM, Kementerian Keuangan, Kementerian Tenaga Kerja dan Transmigrasi, dan Kementerian Pendidikan Nasional. Today, internet service has been widely used for various purposes in order to improve the effectiveness and efficiency of its users. No exception to the government that utilizes the internet to provide services and information to their communities. This study discusses about the online services provided by government to find out the extent to which the application of e-government conducted by the government at the Ministry level framework based on Deloitte & Touche. The scope of this study is the site of the Ministry and its directorate, the approach used to map the level of e-government framework that Deloitte & Touche, and other categories of e-government Government-to-Citizen (G2C) serve as the focus of this research. The method used in this study is a quantitative method. The result of this research is the implementation of e-government at the Ministry level has reached the second level, the stage of "official" two-way transactions. Ministry that has reached this stage include the Ministry of Justice, Ministry of Finance, Ministry of Manpower and Transmigration and the Ministry of National Education

    The Effects Of Aerosol-Based Cell Delivery Technique On The Regeneration And Repair Of Airway Epithelium

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    Aerosol-based cell delivery is a potential therapeutic strategy to overcome the debilitating reparative capacity of trachea and lung following injury. The goal of this study was to determine the effect of aerosol-based airway epithelial cell (AEC) delivery on tracheal repair and regeneration, lung damage, and local inflammatory responses in the setting of acute lung injury (ALI) induced by tracheal brushing in rabbit. AECs were isolated from the trachea of New Zealand white rabbits. In vitro aerosol delivery was performed to assess the viability of the cells. Brushing-induced tracheal injury was performed in a rabbit model to develop ALI. One day following injury, exogenous BrdU-labelled AECs were aerosolized using the MicroSprayer® Aerosolizer into the injured airway

    A Bayesian method for finding interactions in genomic studies

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    An important step in building a multiple regression model is the selection of predictors. In genomic and epidemiologic studies, datasets with a small sample size and a large number of predictors are common. In such settings, most standard methods for identifying a good subset of predictors are unstable. Furthermore, there is an increasing emphasis towards identification of interactions, which has not been studied much in the statistical literature. We propose a method, called BSI (Bayesian Selection of Interactions), for selecting predictors in a regression setting when the number of predictors is considerably larger than the sample size with a focus towards selecting interactions. Latent variables are used to infer subset choices based on the posterior distribution. Inference about interactions is implemented by a constraint on the latent variables. The posterior distribution is computed using the Gibbs Sampling methods. The finite-sample properties of the proposed method are assessed by simulation studies. We illustrate the BSI method by analyzing data from a hypertension study involving Single Nucleotide Polymorphisms (SNPs)

    Public Trust in Health Information Sharing: A Measure of System Trust

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/142931/1/hesr12654.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/142931/2/hesr12654_am.pd

    Identification of genes associated with complex traits by testing the genetic dissimilarity between individuals

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    Abstract Using the exome sequencing data from 697 unrelated individuals and their simulated disease phenotypes from Genetic Analysis Workshop 17, we develop and apply a gene-based method to identify the relationship between a gene with multiple rare genetic variants and a phenotype. The method is based on the Mantel test, which assesses the correlation between two distance matrices using a permutation procedure. Using up to 100,000 permutations to estimate the statistical significance in 200 replicate data sets, we found that the method had 5.1% type I error at an α level of 0.05 and had various power to detect genes with simulated genetic associations. FLT1 and KDR had the most significant correlations with Q1 and were replicated 170 and 24 times, respectively, in 200 simulated data sets using a Bonferroni corrected p-value of 0.05 as a threshold. These results suggest that the distance correlation method can be used to identify genotype-phenotype association when multiple rare genetic variants in a gene are involved.http://deepblue.lib.umich.edu/bitstream/2027.42/112957/1/12919_2011_Article_1171.pd
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