237 research outputs found

    Online Contextual Influence Maximization in social networks

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    In this paper, we propose the Online Contextual Influence Maximization Problem (OCIMP). In OCIMP, the learner faces a series of epochs in each of which a different influence campaign is run to promote a certain product in a given social network. In each epoch, the learner first distributes a limited number of free-samples of the product among a set of seed nodes in the social network. Then, the influence spread process takes place over the network, other users get influenced and purchase the product. The goal of the learner is to maximize the expected total number of influenced users over all epochs. We depart from the prior work in two aspects: (i) the learner does not know how the influence spreads over the network, i.e., it is unaware of the influence probabilities; (ii) influence probabilities depend on the context. We develop a learning algorithm for OCIMP, called Contextual Online INfluence maximization (COIN). COIN can use any approximation algorithm that solves the offline influence maximization problem as a subroutine to obtain the set of seed nodes in each epoch. When the influence probabilities are Hölder continuous functions of the context, we prove that COIN achieves sublinear regret with respect to an approximation oracle that knows the influence probabilities for all contexts. Moreover, our regret bound holds for any sequence of contexts. We also test the performance of COIN on several social networks, and show that it performs better than other methods. © 2016 IEEE

    Dephasing of Electrons on Helium by Collisions with Gas Atoms

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    The damping of quantum effects in the transport properties of electrons deposited on a surface of liquid helium is studied. It is found that due to vertical motion of the helium vapour atoms the interference of paths of duration tt is damped by a factor exp(t/τv)3\exp - (t/\tau_v)^3. An expression is derived for the weak-localization lineshape in the case that damping occurs by a combination of processes with this type of cubic exponential damping and processes with a simple exponential damping factor.Comment: 7 pages, 2 figures, Revte

    Dephasing Times in a Non-degenerate Two-Dimensional Electron Gas

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    Studies of weak localization by scattering from vapor atoms for electrons on a liquid helium surface are reported. There are three contributions to the dephasing time. Dephasing by the motion of vapor atoms perpendicular to the surface is studied by varying the holding field to change the characteristic width of the electron layer at the surface. A change in vapor density alters the quasi-elastic scattering length and the dephasing due to the motion of atoms both perpendicular and parallel to the surface. Dephasing due to the electron-electron interaction is dependent on the electron density.Comment: 4 pages, Revte

    Invariance of Charge of Laughlin Quasiparticles

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    A Quantum Antidot electrometer has been used in the first direct observation of the fractionally quantized electric charge. In this paper we report experiments performed on the integer i = 1, 2 and fractional f = 1/3 quantum Hall plateaus extending over a filling factor range of at least 27%. We find the charge of the Laughlin quasiparticles to be invariantly e/3, with standard deviation of 1.2% and absolute accuracy of 4%, independent of filling, tunneling current, and temperature.Comment: 4 pages, 5 fig

    Epilobium hirsutum alters xenobiotic metabolizing CYP1A1, CYP2E1, NQO1 and GPx activities, mRNA and protein levels in rats

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    Context: Natural products have attracted increasing interests due to their use in flavoring, nutrition, cosmetics, pharmacy and medicine. Epilobium hirsutum L. (Onagraceae) is known for its analgesic, antimicrobial, and antiproliferative activity. CYP1A1 and CYP2E1, xenobiotic metabolizing enzymes, serve as a metabolic activation route yielding reactive metabolites that are eliminated by the action of NQO1 and glutathione peroxidase (GPx) enzymes. Objective: This study investigated in vivo effects of Epilobium hirsutum (EH) on CYP2E1, CYP1A1, NQO1 and GPx activities, protein and mRNA expressions in liver. Materials and methods: Male Wistar Albino rats were injected with EH at a dose of 37.5mg/kg i.p. daily for 9d. CYP2E1, CYP1A1, NQO1 and GPx activities, protein and mRNA levels were determined by enzyme assays, Western blotting and qPCR, respectively. Results: CYP1A1 associated ethoxyresorufin-O-deethylase activity of control and EH-treated animals were found as 6.54±1.21 and 4.48±1.67nmol/min/mg, respectively. CYP2E1 associated aniline 4-hydroxylase of control and EH group were 0.537±0.011 and 0.109±0.01nmol/min/mg, respectively. However, EH treatment increased the GPx and NQO1 activities from 0.069±0.015 to 0.107±0.026nmol/min/mg and from 163.34±92 to 588.3±14nmol/min/mg, respectively. Furthermore, protein and mRNA expression analysis revealed that CYP1A1 and CYP2E1 levels were decreased while those of NQO1 and GPx increased after EH treatment. Discussion and conclusion: Our current data suggest that the metabolism of xenobiotics, including drugs, may be altered due to changes in the expression and activity of these proteins by EH. © 2013 Informa Healthcare USA, Inc

    Resistance fluctuations and Aharonov-Bohm-type oscillations in antidot arrays in the quantum Hall regime

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    Resistance fluctuation phenomenon in antidot lattices in the quantum Hall regime are studied. Magnetoresistance of finite antidot array systems in the quantum Hall plateau transition regime exhibits two types of oscillatory effect. One is the aperiodic resistance fluctuations (RFs) and the other is the Aharonov-Bohm (AB)-type oscillations. Their dependences on the magnetic field and the gate voltage are quite distinct. While the aperiodic RFs are attributed to the complex evolution of the conducting network of compressible channels, the AB-type oscillations are interpreted in terms of edge states formed around individual antidots. The self-consistent screening effect is important for the both phenomenon, whereas, the single electron charging effect plays a minor role in the present case.Comment: 5 pages, 4 figure

    Global mortality and readmission rates following COPD exacerbation-related hospitalisation: a meta-analysis of 65 945 individual patients

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    \ua9 2024, European Respiratory Society. All rights reserved.Background Exacerbations of COPD (ECOPD) have a major impact on patients and healthcare systems across the world. Precise estimates of the global burden of ECOPD on mortality and hospital readmission are needed to inform policy makers and aid preventive strategies to mitigate this burden. The aims of the present study were to explore global in-hospital mortality, post-discharge mortality and hospital readmission rates after ECOPD-related hospitalisation using an individual patient data meta-analysis (IPDMA) design. Methods A systematic review was performed identifying studies that reported in-hospital mortality, postdischarge mortality and hospital readmission rates following ECOPD-related hospitalisation. Data analyses were conducted using a one-stage random-effects meta-analysis model. This study was conducted and reported in accordance with the PRISMA-IPD statement. Results Data of 65 945 individual patients with COPD were analysed. The pooled in-hospital mortality rate was 6.2%, pooled 30-, 90- and 365-day post-discharge mortality rates were 1.8%, 5.5% and 10.9%, respectively, and pooled 30-, 90- and 365-day hospital readmission rates were 7.1%, 12.6% and 32.1%, respectively, with noticeable variability between studies and countries. Strongest predictors of mortality and hospital readmission included noninvasive mechanical ventilation and a history of two or more ECOPD-related hospitalisation
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