10 research outputs found
Maternal age as an influencing factor of obstetrical and neonatal outcomes - retrospective studies in Southeastern Hungary
Adverse Maternal and Perinatal Outcome of Women Aged 40 Years or Over: A Retrospective Study
Adverse perinatal outcome in teenage pregnancies: an analysis of a 5-year period in Southeastern Hungary
Association between sociodemographic, obstetric, and lifestyle factors among Hungarian pregnant women鈥擜 cross鈥恠ectional study
Anti-chlamydial effect of plant peptides
Even in asymptomatic cases of Chlamydia trachomatis infection, the aim of the antibiotic strategy is eradication of the pathogen so as to avoid the severe late sequelae, such as pelvic inflammatory disease, ectopic pregnancy, and tubal infertility. Although first-line antimicrobial agents have been demonstrated to be predominantly successful in the treatment of C. trachomatis infection, treatment failures have been observed in some cases. Rich source of antimicrobial peptides was recently discovered in Medicago species, which act in plants as differentiation factors of the endosymbiotic bacterium partner. Several of these symbiotic plant peptides have proved to be potent killers of various bacteria in vitro. We show here that 7 of 11 peptides tested exhibited antimicrobial activity against C. trachomatis D, and that the killing activity of these peptides is most likely due to their interaction with specific bacterial targets