Partial b_{v}(s) and b_{v}({\theta}) metric spaces and related fixed point theorems

In this paper, we introduced two new generalized metric spaces called partial b_{v}(s) and b_{v}({\theta}) metric spaces which extend b_{v}(s) metric space, b-metric space, rectangular metric space, v-generalized metric space, partial metric space, partial b-metric space, partial rectangular b-metric space and so on. We proved some famous theorems such as Banach, Kannan and Reich fixed point theorems in these spaces. Also, we give definition of partial v-generalized metric space and show that these fixed point theorems are valid in this space. We also give numerical examples to support our definitions. Our results generalize several corresponding results in literature.Comment: 15 page

PARTIAL b_{v}(s), PARTIAL v-GENERALIZED AND b_{v}(θ) METRIC SPACES AND RELATED FIXED POINT THEOREMS

In this paper, we have introduced three new generalized metric spaces called partial $b_{v}\left( s\right)$, partial $v$-generalized and $b_{v}\left(\theta \right)$ metric spaces which extend $b_{v}\left( s\right)$ metricspace, $b$-metric space, rectangular metric space, $v$-generalized metricspace, partial metric space, partial $b$-metric space, partial rectangular $$-metric space and so on. We have proved some famous theorems such as Banach, Kannan and Reich fixed point theorems in these spaces. Also, we have given somenumerical examples to support our definitions. Our results generalize several corresponding results in literature

Is YouTube a quality source of information on sarcopenia?

Background: While sarcopenia is a prevalent disorder that affects muscle mass and quality, patients have limited knowledge of it. On the other hand, patients often use social media to obtain health-specific information. Therefore, the aim of this study was to investigate the YouTube videos about sarcopenia in terms of the knowledge value of what they present and to identify which of them can be considered as the quality sources of such information. Methods: The descriptive study included 53 videos retrieved by searching the keywords ‘sarcopenia’, ‘loss of muscle strength’, ‘sarcopenia treatment,’ ‘sarcopenia physiotherapy,’ and’sarcopenia rehabilitation’ on YouTube. The instructive characteristics of the videos were assessed with the Global Quality Scale, by which three quality groups were identified: poor-, moderate-, and high-quality videos. The DISCERN score was utilized to determine reliability. The sources of upload were identified as physicians, non-physician health personnel, health-related websites, universities and academic organizations, patients, and independent users. Finally, the lengths of videos, the number of views, likes, dislikes, and comments, and the DISCERN scores of the videos were compared using group comparisons. Results: The results suggested that there were 18 poor-quality, 16 moderate-quality, and 19 high-quality videos. Considering the sources of upload, physicians had the highest ratio in the high-quality group (83.3%). The lengths of videos and the DISCERN scores showed significant differences (p < 0.01). The numbers of views, likes, dislikes, and comments were similar in both quality and source groups. Conclusion: Most parts of the videos uploaded by physicians and academic organizations were included in the high-quality group. Overall, according to the results of the study, it can be asserted that high quality may be related to reliability. Furthermore, healthcare professionals and academics should consider using YouTube for increasing knowledge and raising awareness of patients about sarcopenia. © 2020, European Geriatric Medicine Society

Clopidogrel versus ticagrelor in chronic kidney disease patients presenting with acute coronary syndrome: A retrospective evaluation

Aim: To compare the efficacy and bleeding risk of clopidogrel versus ticagrelor in patients presenting with the acute coronary syndrome (ACS). Method: This was a single-center retrospective comparison of in-hospital and 1-year major advance cardiovascular events (MACE) in patients with ACS and reduced estimated glomerular filtration rate (eGFR &lt;60 mL/min) who were treated with clopidogrel or ticagrelor in addition to aspirin. Clinicodemographic features, medication use, and laboratory values were recorded. eGFR was calculated by means of the modification of diet in renal disease (MDRD) equation. The Killip classification was used to quantify the severity of heart failure. The primary outcome measures were in-hospital and 1-year MACEs and major and minor bleeding. MACE definition included recurrent myocardial infarction, stroke, and cardiovascular death. Results: In total, 235 patients (40.9% female, mean age 67.8 ± 12.4 years) were included. Of all patients, 56% presented with ST-elevation myocardial infarction (STEMI), whereas 44% had a non-ST-elevation myocardial infarction. Sixty-eight patients were treated with ticagrelor, while 167 patients were administered clopidogrel. The groups were comparable in terms of in-hospital mortality, cerebrovascular accident (CVA), and re-infarction rates. There was no statistical difference between the mortality, CVA and re-infarction rates between the groups at 12-month. In-hospital minor bleedings were more common among ticagrelor users. In-hospital major bleeding frequencies were similar in both groups. There was no statistical difference in terms of major or minor bleeding rates at 12 months. Conclusion: The findings of the present study showed comparable efficacy and bleeding risk in ACS patients who were treated clopidogrel or ticagrelor

IDENTIFICATION OF MEATS USING RANDOM AMPLIFIED POLYMORPHIC DNA (RAPD) TECHNIQUE

Use of a simpler, faster and reliable method for identification of species of origin in fresh and processed meat products is required to prevent unethical practices that may occur in the meat industry. The effectiveness of a random amplified polymorphic DNA (RAPD) method for identification of fresh meats from cattle, goat, sheep, camel, pork, wild swine, donkey, cat, dog, rabbit or bear origin was evaluated using a 10-base primer (ACGACCCACG). The method was also used to determine the species in a 1 : 1 mix of raw minced meat from sheep-pork, horse-beef or beef-sheep. Characteristic RAPD profiles for each species were obtained. However, efficacy of the technique in identifying species in meat mixtures varied depending on the species in the mix. These results indicate that RAPD may be useful for identification of meat samples from single species, such as intact meat samples, whereas caution should be exercised in identification of origin of species in minced meat that may consist of multiple species

Effects of Comorbidities, Inflammation and Glycaemic Control on Length of Hospital Stay/Potentially Avoidable Readmission Risk in Type 2 Diabetic Patients- A Retrospective Analysis

karahan, irfan/0000-0003-4669-1751WOS: 000500570300001BACKGROUND Patients with diabetes can have long hospitalization and frequent readmissions for different reasons. Predicting the duration of hospitalization and readmission risk may be helpful for management. We wanted to identify factors that affect the length of hospital stay and potentially avoidable readmission risk. METHODS 102 type 2 adults with diabetes that were hospitalized and discharged between July 2017 and July 2018 in Kirikkale University, Department of Internal Medicine, were investigated retrospectively. HOSPITAL score was calculated for detecting 30-day readmission risk. Haemoglobin A1c for glycaemic control, C-reactive protein/serum albumin ratio (CAR) for inflammation, Charlson comorbidity score for multimorbidities, and age were researched as factors that affect the length of stay/ HOSPITAL score. RESULTS There were 70 female and 32 male patients. The median age of participants was 69. Median HbA1c was 9.2%, median Charlson comorbidity score was 6, median CAR was 3.33, median HOSPITAL score was 4. Significant positive correlation was detected between age, Charlson comorbidity score, CAR, HbA1c level and both hospital length of stay/HOSPITAL score by Spearman's correlation analysis. However, Charlson comorbidity score and CAR had significant values with both length of hospital stay/ HOSPITAL score according to the linear regression model. CONCLUSIONS Identifying the factors that affect readmission and length of stay, benefits hospitalized diabetes patient management. This can have favourable impact on costs, sources and approach. Type 2 diabetes patients can have multiple comorbidities and inflammatory conditions. Inflammation and comorbidity presence have negative effects on length of stay and avoidable readmission. Presence of these indices' in high levels should be considered high risk for readmission and these patients should be evaluated carefully

The COVID-19 anxiety of hospitalised patients in a palliative care unit

WOS:000563780900002PubMed: 32841081[Özet Yok

A GENERAL VIEW TO COSTS FOR THE HOSPITALIZED PATIENTS IN PALLIATIVE CARE UNIT: A SINGLE CENTRE EXPERIENCE

AMAÇ: Palyatif bakım, yaşamı tehdit eden hastalıkları olan bireylerde yaşam kalitesini artırmayı hedefleyen yaklaşım olarak özetlenebilir. Ülkemizde palyatif bakım ünitelerinin sayısı son zamanlarda artmış olup, harcamalarıyla ilgili ayrıntılı veri bulunmamaktadır. Bu çalışmada hastanemiz palyatif bakım ünitesindeki harcama gruplarının belirlenmesi amaçlanmıştır. GEREÇ VE YÖNTEM: Kırıkkale Üniversitesi, Tıp Fakültesi, İbn-i Sina Palyatif Bakım Ünitesi’nde Mart 2019-Aralık 2019 arasında yatan 333 hastanın arşiv kaydı hasta harcamaları açısından retrospektif olarak incelendi. Harcamalar; ilaçlar ve medikal tedavi, laboratuvar incelemeleri, radyolojik inceleme ve girişimler, tıbbi malzemeler ve diğer harcamalar olarak gruplandı. BULGULAR: Gruplar arasında en pahalı harcama türü ilaç ve medikal tedaviydi. İlaçların içerisinde de en pahalı grubun antibiyotikler olması dikkati çekti. SONUÇ: Giderlerin belirlenmesi; palyatif bakımın doğru kullanımı ve düzgün planlama için önemli olabilir. İlaç ve özellikle antibiyotik giderlerinin ön planda olması akılcı ilaç kullanımının önemini vurgulayabilir.AIM: Palliative care can be defined shortly as an approach that aims to improve the quality of life for life-threating conditions. Recently, the numbers of palliative care units raised, and there is a lack of detailed knowledge about the costs. The present study aimed to investigate the group of costs in the palliative care unit. MATERIAL AND METHOD: The retrospective study was conducted to examine costs through the archive records of 333 in patients in Kırıkkale University, School of Medicine, İbn-i Sina Palliative Care Unit between March 2019-December 2019. The cost groups were defined as drugs and medical treatment, laboratory investigations, radiological procedures, medical equipment, and others. RESULTS: Between the main groups, the most expensive group was drugs and medical treatment, and the most expensive medications were antibiotics. CONCLUSION: Defining expenses may be important for the correct use of palliative care and well-planning. The fact that drugs and especially antibiotic expenses are at the forefront can emphasize the importance of rational drug use

Are Lipoprotein Levels and Ratios Able to Predict Mortality due to Sepsis?

karahan, irfan/0000-0003-4669-1751WOS: 000520024700010PubMed: 32169135Objective: To compare lipoprotein levels, and non-HDL to high-density lipoprotein (HDL) ratios of survivors and nonsurvivors of sepsis, and to determine the predictivity levels of specified parameters in mortality. Study Design: Descriptive study. Place and Duration of Study: Department of Internal Medicine, Kirikkale University, School of Medicine, Training and Research Hospital, Kirikkale, Turkey, from December 2017 to December 2018. Methodology: The study subjects included 37 non-survivors and 32 survivors of sepsis with similar ages, comorbidities, and disease activities. The total lipoprotein levels, and non-HDL to HDL ratios of the participants were compared retrospectively. Results: HDL and non-HDL to HDL ratios were found to be different between the two groups. The cut-off levels of these values were determined as 32 and 3.4, respectively. The cut-off levels found in the study suggest that the low HDL levels and high non-HDL to HDL ratios significantly increase the mortality risk for patients (OR=1.8 and 3.45, respectively). Conclusion: Non-HDL to HDL ratio may be used as a useful tool for predicting sepsis mortality. These values may also be included as a part of scoring systems. Further investigations are needed to clarify the role of lipoproteins in sepsis

Palyatif bakım ünitesinde yatan hastalar için yapılan harcamalara genel bakış: Tek merkez deneyimi

AMAÇ: Palyatif bakım, yaşamı tehdit eden hastalıkları olan bireylerde yaşam kalitesini artırmayı hedefleyen yaklaşım olarak özetlenebilir. Ülkemizde palyatif bakım ünitelerinin sayısı son zamanlarda artmış olup, harcamalarıyla ilgili ayrıntılı veri bulunmamaktadır. Bu çalışmada hastanemiz palyatif bakım ünitesindeki harcama gruplarının belirlenmesi amaçlanmıştır. GEREÇ VE YÖNTEM: Kırıkkale Üniversitesi, Tıp Fakültesi, İbn-i Sina Palyatif Bakım Ünitesi’nde Mart 2019-Aralık 2019 arasında yatan 333 hastanın arşiv kaydı hasta harcamaları açısından retrospektif olarak incelendi. Harcamalar; ilaçlar ve medikal tedavi, laboratuvar incelemeleri, radyolojik inceleme ve girişimler, tıbbi malzemeler ve diğer harcamalar olarak gruplandı. BULGULAR: Gruplar arasında en pahalı harcama türü ilaç ve medikal tedaviydi. İlaçların içerisinde de en pahalı grubun antibiyotikler olması dikkati çekti. SONUÇ: Giderlerin belirlenmesi; palyatif bakımın doğru kullanımı ve düzgün planlama için önemli olabilir. İlaç ve özellikle antibiyotik giderlerinin ön planda olması akılcı ilaç kullanımının önemini vurgulayabilir.AIM: Palliative care can be defined shortly as an approach that aims to improve the quality of life for life-threating conditions. Recently, the numbers of palliative care units raised, and there is a lack of detailed knowledge about the costs. The present study aimed to investigate the group of costs in the palliative care unit. MATERIAL AND METHOD: The retrospective study was conducted to examine costs through the archive records of 333 in patients in Kırıkkale University, School of Medicine, İbn-i Sina Palliative Care Unit between March 2019-December 2019. The cost groups were defined as drugs and medical treatment, laboratory investigations, radiological procedures, medical equipment, and others. RESULTS: Between the main groups, the most expensive group was drugs and medical treatment, and the most expensive medications were antibiotics. CONCLUSION: Defining expenses may be important for the correct use of palliative care and well-planning. The fact that drugs and especially antibiotic expenses are at the forefront can emphasize the importance of rational drug use