Helicobacter pylori Seropositivity and Stool Antigen in Patients With Hyperemesis Gravidarum

The objective of this paper is to investigate whether Helicobacter pylori is an etiologic factor in hyperemesis gravidarum. Thirty one patients with hyperemesis gravidarum and twenty nine pregnant controls without hyperemesis gravidarum were included in this prospective study. All pregnant women were examined both for Helicobacter pylori serum immunoglobulin G antibodies (HpIgG Ab), showing chronic infection, and Helicobacter pylori stool antigens (HpSA), showing active gastrointestinal colonization. Chi-square and Student t tests were used accordingly for statistical analysis. Helicobacter pylori seropositivity was 67.7% in the patients with hyperemesis gravidarum and 79.3% in the control group (χ(2) = 1.02, P = .31). HpSA was detected in 22.6% of patients with hyperemesis gravidarum, whereas 6.9% of patients in the control group. The difference was not statistically significant (χ(2) = 2.89, P = .08). In this study, no relation was found between Helicobacter pylori and hyperemesis gravidarum. The low social status of women in both groups could be one of the reasons for the high prevalence of Hp infection

Patterns of multiple primaries in fortyfour cancer patients: a single-center clinical experience

Introduction. Multiple primaries are defined as the existence of more than one synchronous or metachronous cancer type in the same individual. Due to a longer follow-up time after a primary cancer diagnosis, the likelihood of detection of a second primary is also increased. We report on patterns of multiple primaries in a cohort of cancer patients from a single institution.  Material and methods. We identified 44 patients with multiple primaries that were diagnosed, treated, and followed up between March 2011 and January 2022 from our prospectively maintained database at the Hatay Education and Research Hospital Cancer Unit.  Results. The median follow-up time was 60 months (range; 3–103). The median time between the diagnosis of the first primary and the second primary was 29 months (range; 0–94). The median OS was 76 months (95% Cl 26.6–125.4) from the first diagnosis and 27 months (95% Cl 0.65–53.4) from the diagnosis of the second primary for the entire cohort. The first diagnosed tumor was localized in the gastrointestinal system in 43.2% of patients and 65.9% of all tumors were adenocarcinoma. The first diagnosed cancer was at an early stage (Stages I and II) in 63.6% of patients. At the staging evaluation of the second primary, 54.5% of patients were found to be in the early stage (Stages I and II) and 45.5% were found to be in the late stage (Stages III and IV).  Conclusions. Our study is important as this is the largest cohort study about practical implications of managing multiple primaries. The risk of second and further primaries should be kept in mind in the active follow-up Introduction and surveillance of cancer patients

Activity concentrations of natural radionuclides and Cs-137 in soils of coniferous forest sites in West Anatolia

WOS: 000287324900012The surveys of natural gamma-emitting radionuclides and Cs-137 in surface soils of coniferous forest sites in and around Izmir were conducted during 2003-2004. The soil samples were collected from three different depths of 15 forest sites, particularly local wild edible mushrooms areas. The average activity concentrations and ranges of the natural radionuclides in the soils were as follows: 30 (14-51) Bq kg(-1) of Ra-226; 40 (17-79) Bq kg(-1) of Th-232; and 581 (308-879) Bq kg(-1) of K-40. Moreover, the values of Cs-137 activity concentrations averaged over the depth sections varied from 20 to 82 Bq kg(-1) with a mean value of 52 Bq kg(-1). Accordingly, the levels of the studied natural radionuclides in the forest soils were within the range specified by UNSCEAR (2000) report for regular soils as well as the agricultural soils from the West Anatolia, while the measured activity levels of Cs-137 in the forest soils were still high in contrast to agricultural soils after 16 years from the deposition of Chernobyl fallout.Ege UniversityEge University [2003 NBE 006]Grateful thanks are offered to the provider of financial support for the research presented here: Ege University Scientific Research Project (Project no: 2003 NBE 006)

Soil-to-mushroom transfer of Cs-137, K-40, alkali-alkaline earth element and heavy metal in forest sites of Izmir, Turkey

WOS: 000288220400041The present work is devoted to an investigation on the soil to mushroom transfer parameters for Cs-137 and K-40 radionuclides, as well as for some stable elements and heavy metals. The results of transfer factors for Cs-137 and K-40 were within the range of 0.06-3.15 and 0.67-5.68, respectively and the most efficiently transferred radionuclide was K-40. The TF values for Cs-137 typically conformed to a lognormal distribution, while for K-40 showed normal distribution. Statistically significant correlations between Cs-137 soil to mushroom transfer factors and agrochemical soil properties have been revealed. Although the concentration ratios varied within the species, the most efficiently transferred elements seems to have been K, followed by Rb, Zn, Cu, Cd, S, Cs and Hg.Ege UniversityEge University [2003 NBE 006]Grateful thanks are offered to the provider of financial support for the research presented here: Ege University Scientific Research Project (Project no: 2003 NBE 006). The authors also would like to thank Dr. Halil Solak (Mug. la University, Ula Technical High School, Department of Mycology) for his indispensable help during precise identification of the different fungi species, to Mr. Nejat Ozden and Dr. Tolga Esetlili for their collaboration during identification of the different soil horizons, to Mr. Fatih Coban for his help on drawing the figures and the ACME Laboratory for carrying out trace element analyses of mushroom samples

Dynamic equilibrium of radiocesium with stable cesium within the soil-mushroom system in Turkish pine forest

WOS: 000246978900035PubMed ID: 17258362Mushrooms and soils collected from pine forests in izrnir, Turkey were measured for radiocesium and stable Cs in 2002. The ranges of Cs-137 and stable Cs concentrations in mushrooms were 9.84 +/- 1.67 to 401 +/- 3.85 Bq kg(-1) dry weight and 0.040 +/- 0.004 to 11.3 +/- 1.09 mg kg(-1) dry weight, respectively. The concentrations of Cs-137 and stable Cs in soils were 0.29 +/- 0.18 to 161 +/- 1.12 Bq kg(-1) dry weight and 0.14 +/- 0.004 to 1.44 +/- 0.045 mg kg(-1) dry weight, respectively. Even though different species were included, the concentration ratios of Cs-137 to stable Cs were fairly constant for samples collected at the same forest site, and were in the same order of magnitude as the Cs-137 to stable Cs ratios for the organic soil layers. The soil-to-mushroorn transfer factors of 137Cs and stable Cs were in the range of 0.19-3.15 and 0.17-12.3, respectively. The transfer factors of Cs-137 were significantly correlated to those of stable Cs. (C) 2006 Elsevier Ltd. All rights reserved

Rapid eye movement sleep without atonia constitutes increased risk for neurodegenerative disorders

Objectives REM (rapid eye movement) sleep without atonia (RSWA) is a polysomnographic finding used in diagnosis of REM sleep behavior disorder (RBD). Clinical significance of idiopathic RSWA (iRSWA) unaccompanied by RBD is not known. We designed a prospective study to investigate whether iRSWA constitutes an increased risk for developing neurodegenerative disorders. Materials and methods Between January 2010 and December 2014, a total of 4362 patients underwent a full-night video-polysomnography. Upon detailed clinical and polysomnographical examination, patients with iRSWA and idiopathic RBD (iRBD) were enrolled into this study and followed up at every six months for at least 4 years up to 9 years. Results We had a total of 31 patients with iRBD and 67 patients with iRSWA. Mean age was higher in iRBD group than those in iRSWA group (P = .016). Restless legs syndrome/Willis-Ekbom disease was significantly more common in patients with iRBD than those in patient with iRSWA (P < .001). Eighteen patients with iRSWA (26.8%) developed iRBD after 2.6 + 2.2 years. Six patients with iRSWA (8.9%) developed neurodegenerative disorders following 2.4 + 1.5 years; four were diagnosed as Parkinson's disease (PD) and two developed probable Alzheimer-type dementia. In patients with iRBD, eight patients (25.8%) developed neurodegenerative disorders-all was Parkinson's disease-following 2.6 + 2.2 years. Development of neurodegenerative diseases was positively correlated with age (P < .001) and periodic leg movements in sleep in both groups (P < .010). Conclusions These results show that iRSWA may also be accepted as a risk factor in the development of PD or neurodegenerative diseases. Advanced age and periodic leg movements in sleep seem to be correlated with higher risk

Indoor radon measurements in the granodiorite area of Bergama (Pergamon)-Kozak, Turkey

WOS: 000302299800007PubMed ID: 21636559Indoor radon levels in 20 dwellings of rural areas at the Kozak-Bergama (Pergamon) granodiorite area in Turkey were measured by the alpha track etch integrated method. These dwellings were monitored for eight successive months. Results show that the radon levels varied widely in the area ranging from 111 to 72711 Bq m(3) and the geometric mean was found to be 63 Bq m(3) with a geometric standard deviation of 2 Bq m(3). A lognormal distribution of the radon concentration was obtained for the studied area. Estimated annual effective doses due to the indoor radon ranged from 0.27 to 18.34 mSv y(1) with a mean value of 1.95 mSv y(1), which is lower than the effective dose values 310 mSv given as the range of action levels recommended by International Commission on Radiation Protection. All dosimetric calculations were performed based on the guidance of the UNSCEAR 2000 report.Dokuz Eylul UniversityDokuz Eylul University [2009.KB.FEN.039]This work was supported by Dokuz Eylul University Scientific Research Project (Project no: 2009.KB.FEN.039)

Terrestrial gamma exposure in the granodiorite area of Bergama (Pergamon)-Kozak, Turkey

WOS: 000290040000039As higher radiation levels are associated with granite and Bergama (Pergamon) has increasingly become a large market for granite use over the last years, an extensive investigation was started in 2009. Samples from the granites and soils underlying this area were collected and analyzed by HPGe gamma spectrometry system. The specific activities of the naturally occurring radionuclides Ra-226, Th-232, and K-40 were found to be in the range of 29-111 Bq kg(-1) for Ra-226, 35-87 Bq kg(-1) for Th-232 and 698-1100 Bq kg(-1) for K-40 in granite samples. The ranges of Ra-226, Th-232, and K-40 activity concentrations for soils were 32-82, 42-88 and 667-1127 Bq kg(-1), respectively. From these data radiological parameters were calculated and compared with respective data from the UNSCEAR reports.Dokuz Eylul UniversityDokuz Eylul University [2009.KB.FEN.039]Grateful thanks are offered to the provider of financial support for the research presented here: Dokuz Eylul University Scientific Research Project (Project no: 2009.KB.FEN.039). The authors also would like to thank graduate and undergraduate students; Mrs. Ipek Emen, Mr. Sadi Deniz Kayhan and Mr. Onur Buyukok for assisting in sample collection, preparation of granites and soils

Persistence of Cs-137 in the litter layers of forest soil horizons of Mount IDA/Kazdagi, Turkey

WOS: 000347596000013PubMed ID: 25464048In 2010-2012, an extensive study was performed in forest sites of Mount IDA (Kazdagi)/Edremit 26 years after the Chernobyl accident. The Cs-137 activity concentrations were determined by gamma-ray spectrometry in the forest soil layers (O-L, O-F + O-H and A horizons) separately. Based on 341 surface soil samples and 118 soil profiles, activity concentrations of 137Cs in O-L horizons varied between 0.25 +/- 0.14 and 70 +/- 1 Bq kg(-1), while the ranges of Cs-137 activity concentrations in O-F + O-H and A horizons were 13 +/- 1-555 +/- 3 Bq kg(-1) and 2 +/- 1-253 +/- 2 Bq kg(-1), respectively. Cesium-137 deposition in the study area was estimated to be in the range of 1-39 kBq m(-2) and a linear relationship between the deposition of Cs-137 and the altitude was observed. The distributions of Cs-137 activities in O-L, O-F + O-H and A horizons throughout the region were mapped in detail. The highest Cs-137 activities were found in O-F + O-H horizons, with markedly lower Cs-137 activity in mineral horizons of soil profiles. It is observed that Cs-137 content of humus layer increases with the thickness of the humus layer for coniferous forest sites. The Cs-137 activity concentrations were higher than the recommended screening limits (150 Bq kg(-1)) at some of the investigated areas. The current activity concentration of top soil layers indicates that over many years since the initial deposition, Cs-137 activity is keeping still high in the organic horizons. (C) 2014 Elsevier Ltd. All rights reserved.Scientific and Technical Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [109Y336]Grateful thanks are offered to the provider of financial support for the research presented here: The Scientific and Technical Research Council of Turkey (TUBITAK) (Project no: 109Y336). The authors are also grateful to Prof. Dr. Gunseli Yaprak for professional advice on several aspects of the Gamma spectroscopy, to Mr. Nivazi Ozcankaya for his careful assistance in preparation of forest vegetation map of Kazdagi and to Mr. Huseyin Atay and Ms. Sabiha Vurmaz for assisting in sample collection, preparation of soils

Axillary staging after neoadjuvant chemotherapy: The comparison of surgeon performed axillary ultrasound and 18F-FDG PET/CT with pathologic status of sentinel lymph nodes in clinically node-negative breast cancer

San Antonio Breast Cancer Symposium -- DEC 05-09, 2017 -- San Antonio, TXWOS: 00042548940033