1,230 research outputs found
Information Technology and Healthcare Education: Scope and Opportunities
Information Technology and Healthcare Education: Scope and Opportunitie
Information Technology and Healthcare Education: Scope and Opportunities
Information Technology and Healthcare Education: Scope and Opportunitie
Anti-Inflammatory And Anti-Nociceptive Activities Of Methanolic Extract Of The Leaves Of Fraxinus floribunda Wallich
Fraxinus floribunda Wallich (Family-Oleaceae) is a wide green tree in the sub-alpine region of Sikkim, India. The methanolic extract of the leaves of Fraxinus floribunda (MEFF) at 100, 200 and 400mg/kg/p.o was screened in rats for anti-inflammatory activity by acute-carrageenan induced paw edema, sub-acute cotton pellet induced granuloma and chronic Freund\'s adjuvant induced arthritis models. In all the three models of antiinflammatory studies 200 and 400mg/kg/p.o doses of the extract showed significant effect (
Study - Skin changes in internal malignancy
BACKGROUND: Internal malignancies are accompanied by various skin
changes which may be specific infiltrates or non-specific changes. This
study is aimed at determining the frequency of such changes in
malignant disease treatment center attendees in India. METHODS: A
study of 300 confirmed cases of internal malignancy at a malignant
disease treatment center was undertaken to evaluate these skin changes.
Specific infiltrates were confirmed by histopathology. Statistical
methods were employed to calculate significance in non-specific lesions
by comparing with 300 controls not suffering from internal malignancy.
RESULTS: Skin changes were present in 82 (27.3%). Cutaneous metastases
were found in 19 (6.3%); non-contiguous in 5 (1.6%); contiguous in 14
(4.3%). Non-specific skin lesions numbered 74 (11.6%) in 52 patients.
Statistically significant non-specific skin changes were acquired
ichthyosis, herpes zoster and generalized pruritus. CONCLUSION:
Metastases usually occurred late in internal malignancy (17, 5.6%)
except in a case each of histiocytic lymphoma and non-Hodgkin's
lymphoma (2, 0.7%) where the lesions preceded malignancy by 3 months
and 1 month respectively. Contiguous nodules were a marker of relapse
after surgery in 3 (1%)
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Enhanced piezoelectricity and electromechanical efficiency in semiconducting GaN due to nanoscale porosity
Electrical polarization phenomena in GaN are important as they have significant impact on the operation of modern day energy efficient lighting and are fundamental to many GaN-based high power and high frequency electronics. Controlling polarization is beneficial for the optimization of these applications. GaN is also piezoelectric, and therefore mechanical stress and strain are possible handles to control its polarization. Nonetheless, polar semiconductors in general, and GaN in particular, are weak piezoelectric materials when compared to ceramics, and are therefore not considered for characteristic electromechanical applications such as sensing, actuation and mechanical energy harvesting. Here, we examine the effect of nanoscale porosity on the piezoelectricity of initially conductive GaN. We find that for 40% porosity, the previously conductive GaN layer becomes depleted, and exhibits enhanced piezoelectricity as measured using piezoresponse force microscopy, as well as by using a mechanical energy harvesting setup. The effective piezoelectric charge coefficient of the porous GaN, d33,eff, is found to be about 8 pm/V which is 2 3 times larger than bulk GaN. A macroscale device comprising a porous GaN layer delivered 100 nW/cm2 across a resistive load under a 150 kPa mechanical excitation. We performed finite element simulations to analyze the evolution of the piezoelectric properties with porosity. The simulations suggest that increased mechanical compliance due to porosity gives rise to the observed enhanced piezoelectricity in GaN. Furthermore, the simulations show that for stress-based excitations, the porous GaN electromechanical figure of merit is increased by an order of magnitude and becomes comparable to that of barium titanate piezoceramics. In addition, considering the central role played by GaN in modern electronics and optoelectronics, our study validates a very promising research direction when considering stress-based electromechanical applications which combine GaN’s semiconducting and piezoelectric properties
Discussion on a possible neutrino detector located in India
We have identified some important and worthwhile physics opportunitites with
a possible neutrino detector located in India. Particular emphasis is placed on
the geographical advantage with a stress on the complimentary aspects with
respect to other neutrino detectors already in operation.Comment: 9 pages; arXiv copy of published proceedings contributio
Single lesion multibacillary leprosy, a treatment enigma: a case report
This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens
Prevalence and Risk Factors of Human Papillomavirus (HPV) Infection in Southern Chinese Women – A Population-Based Study
Background: Persistent high-risk type Human papillomavirus (HPV) infection is recognized as a necessary cause of cervical cancer. This study aimed to compare the HPV prevalence and risk factors between women residing in Hong Kong (HK) and Guangzhou (GZ) region of China. Methodology/Principal Findings: A total of 1,570 and 1,369 women were recruited from HK and GZ, respectively. The cytology samples were collected and tested for HPV infection. The overall and type-specific HPV prevalence and the potential risk factors for acquisition of HPV infection were studied. Women with normal cytology in the GZ cohort had significantly higher HPV prevalence (10%) than those in the HK cohort (6.2%, p<0.001). The patterns of the age-specific HPV prevalence were also different between the two cohorts. In the HK cohort, women at the age of 20-29 years old had the highest prevalence and a second peak was observed in the age of ≥60 years old. In the GZ cohort, the highest HPV prevalence was also observed in 20-29 years old but declined as the age increased and a second peak was not seen. HPV16 and HPV52 were the most common high-risk types found in the HK and GZ cohorts, respectively. Age was the most consistently observed independent risk factor for HPV infection in the HK, while the number of sexual partners had association in the GZ cohort. Conclusions/Significance: Our study provides the current status and the epidemiological characteristics of HPV prevalence in Southern Chinese women. The results strongly suggested that population education and the effective cervical cancer screening would be vital in the prevention of cervical cancer. © 2011 Liu et al.published_or_final_versio
Artemisinin Inhibits Chloroplast Electron Transport Activity: Mode of Action
Artemisinin, a secondary metabolite produced in Artemisia plant species, besides having antimalarial properties is also phytotoxic. Although, the phytotoxic activity of the compound has been long recognized, no information is available on the mechanism of action of the compound on photosynthetic activity of the plant. In this report, we have evaluated the effect of artemisinin on photoelectron transport activity of chloroplast thylakoid membrane. The inhibitory effect of the compound, under in vitro condition, was pronounced in loosely and fully coupled thylakoids; being strong in the former. The extent of inhibition was drastically reduced in the presence of uncouplers like ammonium chloride or gramicidin; a characteristic feature described for energy transfer inhibitors. The compound, on the other hand, when applied to plants (in vivo), behaved as a potent inhibitor of photosynthetic electron transport. The major site of its action was identified to be the QB; the secondary quinone moiety of photosystemII complex. Analysis of photoreduction kinetics of para-benzoquinone and duroquinone suggest that the inhibition leads to formation of low pool of plastoquinol, which becomes limiting for electron flow through photosystemI. Further it was ascertained that the in vivo inhibitory effect appeared as a consequence of the formation of an unidentified artemisinin-metabolite rather than by the interaction of the compound per se. The putative metabolite of artemisinin is highly reactive in instituting the inhibition of photosynthetic electron flow eventually reducing the plant growth
Enhanced UV photosensitivity from rapid thermal annealed vertically aligned ZnO nanowires
We report on the major improvement in UV photosensitivity and faster photoresponse from vertically aligned ZnO nanowires (NWs) by means of rapid thermal annealing (RTA). The ZnO NWs were grown by vapor-liquid-solid method and subsequently RTA treated at 700°C and 800°C for 120 s. The UV photosensitivity (photo-to-dark current ratio) is 4.5 × 103 for the as-grown NWs and after RTA treatment it is enhanced by a factor of five. The photocurrent (PC) spectra of the as-grown and RTA-treated NWs show a strong peak in the UV region and two other relatively weak peaks in the visible region. The photoresponse measurement shows a bi-exponential growth and bi-exponential decay of the PC from as-grown as well as RTA-treated ZnO NWs. The growth and decay time constants are reduced after the RTA treatment indicating a faster photoresponse. The dark current-voltage characteristics clearly show the presence of surface defects-related trap centers on the as-grown ZnO NWs and after RTA treatment it is significantly reduced. The RTA processing diminishes the surface defect-related trap centers and modifies the surface of the ZnO NWs, resulting in enhanced PC and faster photoresponse. These results demonstrated the effectiveness of RTA processing for achieving improved photosensitivity of ZnO NWs
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