Distribution of enzymes cleaving pyridine nucleotides in animal tissues

A number of enzymes capable of splitting the pyridine nucleotides have been found in animal tissues. A portion of the DPNase (1) that hydrolyzes the nicotinamide ribose bond of DPN and TPN was reported in the microsomes of rat liver (1). The DPN pyrophosphorylase, first described by Kornberg (2), has been found by Hogeboom and Schneider to be largely localized in the nucleus (3). In previous investigations (4) an enzyme from pigeon liver which splits DPNH and not DPN at the pyrophosphate linkage was described. The present communication deals with the intracellular distribution of enzymes from various species that attack the pyridine coenzymes at the pyrophosphate linkage. The distribution and properties of DPNases from different species and tissues will also be presented

The effect of tetrathionate on the stability and immunological properties of muscle triosephosphate dehydrogenases

Tetrathionate effect on stability and immunological properties of muscle triosephosphate dehydrogenase

Structural and Functional Properties of the H and M Subunits of Lactic Dehydrogenases

Structural and functional properties of H and M protein subunits of lactic dehydrogenase

<a comparative study of the evolution of enzymes and nucleic acids< semi-annual status report, nov. 1, 1964 - apr. 30, 1965

Lactic dehydrogenases and protein immunochemicals in vertebrate evolution - irradiation of nucleic acid

Big Food and Soda Versus Public Health: Industry Litigation Against Local Government Regulations to Promote Healthy Diets

Diets high in fats, sugars, and sodium are contributing to alarming levels of obesity, cardiovascular disease, type 2 diabetes, and certain cancers throughout the United States. Sugary drinks, which include beverages that contain added caloric sweeteners such as flavored milks, fruit drinks, sports drinks, and sodas, are the largest source of added sugar in the American diet and an important causative factor for obesity and other diet-related diseases. City and county governments have emerged as key innovators to promote healthier diets, adopting menu labeling laws to facilitate informed choices and soda taxes, warnings labels, and a soda portion cap to discourage consumption. These measures raise tension between the public health promotion and the food and beverage industry’s interests in maximizing profits. This article analyzes the food and beverage industry’s efforts to undermine local government nutrition promotion measures, including lobbying, funding scientific research, public messaging, and litigation. It examines four case studies (New York City’s soda portion cap, San Francisco’s soda warnings ordinance, and soda taxes in Philadelphia and Cook County), and distills steps that local governments can take to address industry opposition and help ensure the legal viability and political sustainability of key public health interventions

A comparative study of the evolution of enzymes and nucleic acids Semiannual progress report, 1 May - 30 Nov. 1967

Immunological and enzymological approaches to evolution of enzymes and nucleic acid

Constraining Light Colored Particles with Event Shapes

Using recently developed techniques for computing event shapes with Soft-Collinear Effective Theory, LEP event shape data is used to derive strong model-independent bounds on new colored particles. In the effective field theory computation, colored particles contribute in loops not only to the running of alpha_s but also to the running of hard, jet and soft functions. Moreover, the differential distribution in the effective theory explicitly probes many energy scales, so event shapes have strong sensitivity to new particle thresholds. Using thrust data from ALEPH and OPAL, colored adjoint fermions (such as a gluino) below 51.0 GeV are ruled out to 95% confidence level. This is nearly an order-of-magnitude improvement over the previous model-independent bound of 6.3 GeV.Comment: 4 pages, 2 figure

Serendipitous Discovery of An Infrared Bow Shock Near PSR J1549-4848 with Spitzer

We report on the discovery of an infrared cometary nebula around PSR J1549$-$4848 in our Spitzer survey of a few middle-aged radio pulsars. Following the discovery, multi-wavelength imaging and spectroscopic observations of the nebula were carried out. We detected the nebula in Spitzer IRAC 8.0, MIPS 24 and 70 $\mu$m imaging and in Spitzer IRS 7.5--14.4 $\mu$m spectroscopic observations, and also in the WISE all-sky survey at 12 and 22 $\mu$m.These data were analyzed in detail, and we find that the nebula can be described with a standard bow-shock shape, and that its spectrum contains polycyclic aromatic hydrocarbon and H$_2$ emission features. However, it is not certain which object drives the nebula. We analyze the field stars and conclude that none of them can be the associated object because stars with a strong wind or mass ejection that usually produce bow shocks are much brighter than the field stars. The pulsar is approximately 15\arcsec\ away from the region in which the associated object is expected to be located. In order to resolve the discrepancy, we suggest that a highly collimated wind could be emitted from the pulsar and produce the bow shock. X-ray imaging to detect the interaction of the wind with the ambient medium and high-spatial resolution radio imaging to determine the proper motion of the pulsar should be carried out, which will help verify the association of the pulsar with the bow shock nebula.Comment: 9 pages, 5 figures, accepted for publication in Ap

On the Road Again

Billboards, the advertising behemoths that line our highways, did you ever wonder just what happens to them after their month or more appearance on Route 35? I set out to find out the answer to that very question and to find out if the material was suitable for apparel. The answer is: they are taken down and rolled up bundled in a tight dirty roll with duct tape then tossed in a dingy warehouse on the outskirts of an industrial park and after a few months in that state they most likely become part of the local landfill! Discovering this I set out to repurpose a discarded billboard skin into a functional creative garment that would be deemed marketable to the contemporary woman