Residential Choices and Prospective Risks of Nursing Home Entry

Nationally representative estimates of the prospective risk of entry into a nursing home and the likelihood of residing in a nursing home are obtained using data from the Longitudinal Study of Aging: 1984-1990. The roles of demographic characteristics, kin availability, and health status in determining entry into and residence in nursing homes is examined. Caregivers facilitate community residence and reduce the risk of nursing home entry for those with functional limitations. Dementia in combination with functional limitations increases the risk of nursing home entry

Infrared light excites cells by changing their electrical capacitance

Optical stimulation has enabled important advances in the study of brain function and other biological processes, and holds promise for medical applications ranging from hearing restoration to cardiac pace making. In particular, pulsed laser stimulation using infrared wavelengths >1.5 μm has therapeutic potential based on its ability to directly stimulate nerves and muscles without any genetic or chemical pre-treatment. However, the mechanism of infrared stimulation has been a mystery, hindering its path to the clinic. Here we show that infrared light excites cells through a novel, highly general electrostatic mechanism. Infrared pulses are absorbed by water, producing a rapid local increase in temperature. This heating reversibly alters the electrical capacitance of the plasma membrane, depolarizing the target cell. This mechanism is fully reversible and requires only the most basic properties of cell membranes. Our findings underscore the generality of pulsed infrared stimulation and its medical potential