4 research outputs found
Unmournable Bodies: Gothic Postcolonialism and The Spectre of Loss in Arundhati Roy\u27s The God of Small Things and Anuradha Roy\u27s Sleeping on Jupiter
My thesis compares Arundhati Roy’s The God of Small Things and Anuradha Roy’s Sleeping on Jupiter in order to demonstrate how a) each text is a product of its moment and a reflection of corresponding critical thought and b) how an inversion of gothic tropes in Sleeping reflects a changed world dynamic, a melancholic exploration of epistemological and traumatic loss that can be seen not only as a recognition of the continued power of oppressive systems but a reflection on the failure of cosmopolitanism to “rescue” the global subject from her own isolation and recolonization. I claim that this is not only demonstrated by a change in form and how gothic tropes are presented, but in how homosexuality and deviant sexuality in particular is treated, a reminder that even in texts that attempt to condemn and reject colonizing tendencies, the political moment and its theoretical appendages continue to haunt postcolonial discourse, enabling recolonization and restratifying spaces of resistance. I claim that this recognition need not be totalizing or nihilistic, but that in the recognition itself lies the possibility for resistance, an act of rebellion that must be constantly re-enacted in order to deterritorialize what has been captured and displaced, a fluid and imaginative negotiation that, much like literature, is limitless in interpretation and offers readers constant and multiplicitous possibilities for agency in the face of equally fluid oppressive systems. --Provided by the author
Giardia duodenalis assemblages associated with diarrhea in children in South India identified by PCR-RFLP
Giardial diarrhea in a birth cohort of 452 children in an urban slum in South India was characterized. Of the 155 episodes that occurred in 99 children, 73% were acute diarrhea. Children with better educated mothers and a toilet at home had lower odds of acquiring giardial diarrhea, whereas low socioeconomic status and drinking municipal water were associated with greater risk. Children with co-infections tended to have a slightly longer duration of diarrhea (P = 0.061) and showed significantly more wasting after an episode than children with diarrhea resulting from Giardia alone (P = 0.032). Among the 99 cases, 50 diarrheal and 51 asymptomatic Giardia positive samples were genotyped by polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) at the triose phosphate isomerase gene. Assemblage B was predominant both in giardial diarrhea (80%) and asymptomatic giardiasis (94%). Children with Assemblage A subgroup-II alone or dual infections with both assemblage A and B had diarrhea more frequently (P = 0.07)
Multisite study of cryptosporidiosis in children with diarrhea in India
Cryptosporidium spp., a common cause of diarrhea in children, were investigated in the first multisite study in India. Diarrheal stools from hospitalized children aged <5 years from Delhi, Trichy, and Vellore were analyzed by microscopy, PCR-restriction fragment length polymorphism (RFLP), and/or sequencing at the small-subunit (SSU) rRNA and Cpgp40/15 loci for species determination and subgenotyping, respectively. Seventy of 2,579 (2.7%) children, 75% of whom were <2 years old, had cryptosporidial diarrhea as determined by microscopy. Genotyping and subgenotyping showed that Cryptosporidium hominis was the most commonly identified species (59/67 children), and subgenotypes Ie, Ia, Ib, and Id were common in all centers. A novel C. parvum subgenotype, IIn, was identified in Vellore. Meteorological analysis revealed a higher rate of cryptosporidial positivity during hotter and drier weather in Delhi
Symptomatic and Asymptomatic Cryptosporidium Infections in Children in a Semi-Urban Slum Community in Southern India
Cryptosporidium is a leading cause of childhood diarrhea in developing countries. We investigated symptomatic and asymptomatic cryptosporidiosis in 20 children less than two years of age in a semi-urban slum in southern India. All surveillance (conducted every two weeks) and diarrheal samples from 20 children (n = 1,036) with cryptosporidial diarrhea previously identified by stool microscopy were tested by polymerase chain reaction–restriction fragment length polymorphism for species and subgenotype determination. Thirty-five episodes of cryptosporidiosis were identified in 20 children, of which 25 were diarrheal. Fifteen episodes were associated with prolonged oocyst shedding. Multiple episodes of cryptosporidiosis occurred in 40% of the children. Most infections were with C. hominis, subtype Ia. Children with multiple infections had significantly lower weight-for-age and height-for-age Z scores at 24 months but had scores comparable with children with a single episode by 36 months. Multiple symptomatic Cryptosporidium infections associated with prolonged oocyst shedding occur frequently in this disease-endemic area and may contribute to the long-term effects of cryptosporidiosis on physical growth in these children