308 research outputs found

    Analysis of fibrinogen variants at gamma 387Ile shows that the side chain of gamma 387 and the tertiary structure of the gamma C-terminal tail are important not only for assembly and secretion of fibrinogen but also for lateral aggregation of protofibrils and XIIIa-catalyzed gamma-gamma dimer formation

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    This research was originally published in Blood. Author(s).Kani, S; Terasawa, F; Yamauchi, K; Tozuka, M; Okumura, N. Title. Blood. 2006;108:1887-1894. © by the American Society of Hematology.ArticleBLOOD. 108(6): 1887-1894 (2006)journal articl

    Is using a tooth brush safe? Successful endoscopic removal of adult tooth brush in two cases and short review

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    Ingestion of foreign bodies is common. However, ingestion of an adult tooth brush and its endoscopic removal is reported rare in literature. Here we report two cases of adult tooth brush ingestion with and without psychiatric illness in the past. Endoscopic removal of the tooth brush was done by using snare and rat tooth forceps differing from other case reports. Hence these cases are peculiar and reported

    Functional analysis of recombinant B beta 15C and B beta 15A fibrinogens demonstrates that B beta 15G residue plays important roles in FPB release and in lateral aggregation of protofibrils

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    The definitive version is available at www.blackwell-synergy.com.ArticleJOURNAL OF THROMBOSIS AND HAEMOSTASIS. 3(5): 983-990 (2005)journal articl

    Applying a values-based decision process to facilitate co-management of threatened species in Aotearoa New Zealand

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    Ko koe ki tēnā, ko ahau ki tēnai kīwai o te kete (you at that, and I at this handle of the basket). This Māori (New Zealanders of indigenous descent) saying conveys the principle of cooperation—we achieve more through working together, rather than separately. Despite decades of calls to rectify cultural imbalance in conservation, threatened species management still relies overwhelmingly on ideas from Western science and on top-down implementation. Values-based approaches to decision making can be used to integrate indigenous peoples’ values into species conservation in a more meaningful way. We used such a values-based method, structured decision making, to develop comanagement of pekapeka (Mystacina tuberculata) (short-tailed bat) and tara iti (Sternula nereis davisae) (Fairy Tern) between Māori and Pākehā (New Zealanders of European descent). We implemented this framework in a series of workshops in which facilitated discussions were used to gather expert knowledge to predict outcomes and make management recommendations. For both species, stakeholders clearly stated their values as fundamental objectives from the start, which allowed alternative strategies to be devised that naturally addressed their diverse values, including mātauranga Māori (Māori knowledge and perspectives). On this shared basis, all partners willingly engaged in the process, and decisions were largely agreed to by all. Most expectations of conflicts between values of Western science and Māori culture were unfounded. Where required, positive compromises were made by jointly developing alternative strategies. The values-based process successfully taha wairua taha tangata (brought both worlds together to achieve the objective) through codeveloped recovery strategies. This approach challenges the traditional model of scientists first preparing management plans focused on biological objectives, then consulting indigenous groups for approval. We recommend values-based approaches, such as structured decision making, as powerful methods for development of comanagement conservation plans between different peoples

    Conformal Invariance and Degrees of Freedom in the QCD String

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    We demonstrate that the Hagedorn-like growth of the number of observed meson states can be used to constrain the degrees of freedom of the underlying effective QCD string. We find that the temperature relevant for such string theories is not given by the usual Hagedorn value TH160T_H\approx 160 MeV, but is considerably higher. This resolves an apparent conflict with the results from a static quark-potential analysis, and suggests that conformal invariance and modular invariance are indeed reflected in the hadronic spectrum. We also find that the D=2D_\perp=2 scalar string is in excellent agreement with data.Comment: 13 pages (Standard LaTeX); --> replaced version emphasizes new results, and agrees with version to appear in Physical Review Letters (Jan 1994

    The shock compression of microorganism-loaded broths and emulsions: Experiments and simulations

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    By carefully selecting flyer plate thickness and the geometry of a target capsule for bacterial broths and emulsions, we have successfully subjected the contents of the capsule to simultaneous shock and dynamic compression when subjected to a flyer-plate impact experiment. The capsules were designed to be recovered intact so that post experimental analysis could be done on the contents. ANSYS® AUTODYN hydrocode simulations were carried out to interrogate the deformation of the cover plate and the wave propagation in the fluid. Accordingly, we have shown that microorganisms such as Escherichia coli, Enterococcus faecalis and Zygosaccharomyces bailii are not affected by this type of loading regime. However, by introducing a cavity behind the broth we were able to observe limited kill in the yeast sample. Further, on using this latter technique with emulsions it was shown that greater emulsification of an oil-based emulsion occurred due to the cavitation that was introduced

    Comments on “Viscous-dissipation effects on the heat transfer in a Poiseuille flow” by O. Aydin and M. Avci

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    This note comments on an article by Aydin and Avci [1]; the paper treats the same problem as that studied analytically by Ou and Cheng [2] and numerically by Hwang et al. [3], namely the effects of viscous- dissipation on forced convection in a parallel plate channel

    Duality in Non-Trivially Compactified Heterotic Strings

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    We study the implications of duality symmetry on the analyticity properties of the partition function as it depends upon the compactification length. In order to obtain non-trivial compactifications, we give a physical prescription to get the Helmholtz free energy for any heterotic string supersymmetric or not. After proving that the free energy is always invariant under the duality transformation Rα/(4R)R\rightarrow \alpha^{'}/(4R) and getting the zero temperature theory whose partition function corresponds to the Helmholtz potential, we show that the self-dual point R0=α/2R_{0}=\sqrt{\alpha^{'}}/2 is a generic singularity as the Hagedorn one. The main difference between these two critical compactification radii is that the term producing the singularity at the self-dual point is finite for any RR0R \neq R_{0}. We see that this behavior at R0R_{0} actually implies a loss of degrees of freedom below that point.Comment: (Preprint No. FTUAM-92/12) 17 page
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