Lupus Myocarditis Presenting as Acute Congestive Heart Failure: A Case Report

A young woman who had a delivery history 3 months previously presented with dyspnea and orthopnea. Initial findings of physical examination, chest radiography, and echocardiogram showed typical congestive heart failure with severe left ventricular (LV) dysfunction. At first, we considered peripartum cardiomyopathy because she had given birth to a baby 3 months previously. However, even though we massively tried conventional drug therapy for 10 days, the patient still remained with refractory heart failure. We performed additional laboratory studies such as complement level and autoantibodies, of which the results supported systemic lupus erythematosus. We could make the diagnosis of acute lupus myocarditis and treated her with corticosteroid. The symptoms were dramatically disappeared and LV function also improved

Identification of Proteins Differentially Expressed in the Conventional Renal Cell Carcinoma by Proteomic Analysis

Renal cell carcinoma (RCC) is one of the most malignant tumors in urology, and due to its insidious onset patients frequently have advanced disease at the time of clinical presentation. Thus, early detection is crucial in management of RCC. To identify tumor specific proteins of RCC, we employed proteomic analysis. We prepared proteins from conventional RCC and the corresponding normal kidney tissues from seven patients with conventional RCC. The expression of proteins was determined by silver stain after two-dimensional polyacrylamide gel electrophoresis (2D-PAGE). The overall protein expression patterns in the RCC and the normal kidney tissues were quite similar except some areas. Of 66 differentially expressed protein spots (p<0.05 by Student t-test), 8 different proteins from 11 spots were identified by MALDI-TOF-MS. The expression of the following proteins was repressed (p<0.05); aminoacylase-1, enoyl-CoA hydratase, aldehyde reductase, tropomyosin α-4 chain, agmatinase and ketohexokinase. Two proteins, vimentin and α-1 antitrypsin precursor, were dominantly expressed in RCC (p<0.05)

Experimental Study on the Heat Transfer Performance of Various Magnet Arrangements in a Closed Space Filled with Ferrofluid

In this study, experiments, simulations, and optimization were performed to evaluate heat transfer performance of ferrofluids. Ferrofluids are colloidal suspensions containing magnetic-nano particles with a diameter of 5 to 15 nm in a base fluid such as oil or water. Recently, as many devices are miniaturized, the design of heat dissipation systems are being diversified to consider cost and safety, and it is becoming important to separate an ancillary device for cooling from main unit. In ferrofluids, the behavior and vortex of magnetic-nano particles are actively generated by an external magnetic field, and the cooling system can be designed in a simplified manner by using this characteristic. The main design parameter is the arrangement of permanent magnets, and the output variable is the temperature inside the magnetic nanofluid. The permanent magnet can be moved up and down, and the temperature inside the magnetic nanofluid was measured at various locations. A predictive model was created using a design of experiments (DOE) and response surface method (RSM) using selected design and temperature variables. Based on the generated regression model, an optimization was applied to find a permanent magnet arrangement that maximizes heat transfer performance. Through the optimization technique used in this study, economic efficiency in terms of time and cost was obtained by reducing the number of experiments

Experimental Study on the Heat Transfer Performance of Various Magnet Arrangements in a Closed Space Filled with Ferrofluid

In this study, experiments, simulations, and optimization were performed to evaluate heat transfer performance of ferrofluids. Ferrofluids are colloidal suspensions containing magnetic-nano particles with a diameter of 5 to 15 nm in a base fluid such as oil or water. Recently, as many devices are miniaturized, the design of heat dissipation systems are being diversified to consider cost and safety, and it is becoming important to separate an ancillary device for cooling from main unit. In ferrofluids, the behavior and vortex of magnetic-nano particles are actively generated by an external magnetic field, and the cooling system can be designed in a simplified manner by using this characteristic. The main design parameter is the arrangement of permanent magnets, and the output variable is the temperature inside the magnetic nanofluid. The permanent magnet can be moved up and down, and the temperature inside the magnetic nanofluid was measured at various locations. A predictive model was created using a design of experiments (DOE) and response surface method (RSM) using selected design and temperature variables. Based on the generated regression model, an optimization was applied to find a permanent magnet arrangement that maximizes heat transfer performance. Through the optimization technique used in this study, economic efficiency in terms of time and cost was obtained by reducing the number of experiments

Stereo Vision-Based High Dynamic Range Imaging Using Differently-Exposed Image Pair

In this paper, a high dynamic range (HDR) imaging method based on the stereo vision system is presented. The proposed method uses differently exposed low dynamic range (LDR) images captured from a stereo camera. The stereo LDR images are first converted to initial stereo HDR images using the inverse camera response function estimated from the LDR images. However, due to the limited dynamic range of the stereo LDR camera, the radiance values in under/over-exposed regions of the initial main-view (MV) HDR image can be lost. To restore these radiance values, the proposed stereo matching and hole-filling algorithms are applied to the stereo HDR images. Specifically, the auxiliary-view (AV) HDR image is warped by using the estimated disparity between initial the stereo HDR images and then effective hole-filling is applied to the warped AV HDR image. To reconstruct the final MV HDR, the warped and hole-filled AV HDR image is fused with the initial MV HDR image using the weight map. The experimental results demonstrate objectively and subjectively that the proposed stereo HDR imaging method provides better performance compared to the conventional method

Hyperparameter Tuning of OC-SVM for Industrial Gas Turbine Anomaly Detection

Gas turbine failure diagnosis is performed in this work based on seven types of tag data consisting of a total of 7976 data. The data consist of about 7000 normal data and less than 500 abnormal data. While normal data are easy to extract, failure data are difficult to extract. So, this study mainly is composed of normal data and a one-class support vector machine (OC-SVM) is used here, which has an advantage in classification accuracy performance. To advance the classification performance, four hyperparameter tuning (manual search, grid search, random search, Bayesian optimization) methods are applied. To analyze the performance of each technique, four evaluation indicators (accuracy, precision, recall, and F-1 score) are used. As a result, about 54.3% of the initial failure diagnosis performance is improved up to 64.88% through the advanced process in terms of accuracy

Impact of height difference between coronary ostium and location of intracoronary pressure sensor on fractional flow reserve measurements.

BackgroundDuring fractional flow reserve (FFR) measurements, distal coronary pressure (Pd) can be influenced by hydrostatic pressure changes resulting from the height difference (HD) between the coronary ostium and the location of the distal pressure sensor.AimsWe investigated the effect of aortocoronary HD on the FFR measurements in each coronary artery.MethodsIn this retrospective cohort study, we analyzed 257 patients who underwent FFR measurements and coronary computed tomography (CCTA) within a year. Using CCTA, we measured HD as the vertical distance between the coronary ostium and a matched point of the distal coronary pressure sensor identified on coronary angiography.ResultsThe location of the Pd sensor was higher than the coronary ostium in the left anterior descending artery (LAD) (-4.64 ± 1.15 cm) and lower than the coronary ostium in the left circumflex artery (LCX) (2.54 ± 1.05 cm) and right coronary artery (RCA) (2.03 ± 1.28 cm). The corrected FFR values by HD were higher in the LAD (0.78 ± 0.09 to 0.82 ± 0.09, PConclusionHD between the coronary ostium and the distal coronary pressure sensor may affect FFR measurements and FFR-guided treatment decisions for coronary artery disease