264 research outputs found
Technical Report on Deploying a highly secured OpenStack Cloud Infrastructure using BradStack as a Case Study
Cloud computing has emerged as a popular paradigm and an attractive model for
providing a reliable distributed computing model.it is increasing attracting
huge attention both in academic research and industrial initiatives. Cloud
deployments are paramount for institution and organizations of all scales. The
availability of a flexible, free open source cloud platform designed with no
propriety software and the ability of its integration with legacy systems and
third-party applications are fundamental. Open stack is a free and opensource
software released under the terms of Apache license with a fragmented and
distributed architecture making it highly flexible. This project was initiated
and aimed at designing a secured cloud infrastructure called BradStack, which
is built on OpenStack in the Computing Laboratory at the University of
Bradford. In this report, we present and discuss the steps required in
deploying a secured BradStack Multi-node cloud infrastructure and conducting
Penetration testing on OpenStack Services to validate the effectiveness of the
security controls on the BradStack platform. This report serves as a practical
guideline, focusing on security and practical infrastructure related issues. It
also serves as a reference for institutions looking at the possibilities of
implementing a secured cloud solution.Comment: 38 pages, 19 figures
Simulated projections for summer monsoon climate over India by a high-resolution regional climate model (PRECIS)
Impact of global warming on the Indian monsoon climate is examined using Hadley Centre's highresolution regional climate model, PRECIS (Providing REgional Climates for Impact Studies). Three simulations from a 17-member Perturbed Physics Ensemble generated using Hadley Center Coupled Model (HadCM3) for the Quantifying Uncertainty in Model Predictions (QUMP) project, are used to drive PRECIS. The PRECIS simulations corresponding to the IPCCSRES A1B emission scenario are carried out for a continuous period of 1961-2098. The model shows reasonable skill in simulating the monsoon climate over India. The climate projections are examined over three time slices, viz. short (2020s, i.e. 2011-2040), medium (2050s, i.e. 2041-2070) and long (2080s, i.e. 2071-2098). The model projections indicate significant warming over India towards the end of the 21st century. The summer monsoon precipitation over India is expected to be 9-16 more in 2080s compared to the baseline (1970s, i.e. 1961-1990) under global warming conditions. Also, the rainy days are projected to be less frequent and more intense over central India
Simulated projections for summer monsoon climate over India by a high-resolution regional climate model (PRECIS)
Impact of global warming on the Indian monsoon
climate is examined using Hadley Centre’s highresolution
regional climate model, PRECIS (Providing
REgional Climates for Impact Studies). Three simulations
from a 17-member Perturbed Physics Ensemble
generated using Hadley Center Coupled Model
(HadCM3) for the Quantifying Uncertainty in Model
Predictions (QUMP) project, are used to drive PRECIS.
The PRECIS simulations corresponding to the IPCCSRES
A1B emission scenario are carried out for a continuous
period of 1961–2098. The model shows
reasonable skill in simulating the monsoon climate
over India. The climate projections are examined over
three time slices, viz. short (2020s, i.e. 2011–2040),
medium (2050s, i.e. 2041–2070) and long (2080s, i.e.
2071–2098). The model projections indicate significant
warming over India towards the end of the 21st century.
The summer monsoon precipitation over India is
expected to be 9–16% more in 2080s compared to the
baseline (1970s, i.e. 1961–1990) under global warming
conditions. Also, the rainy days are projected to be
less frequent and more intense over central India
Bilateral Vestibular Dysfunction Associated With Chronic Exposure to Military Jet Propellant Type-Eight Jet Fuel.
We describe three patients diagnosed with bilateral vestibular dysfunction associated with the jet propellant type-eight (JP-8) fuel exposure. Chronic exposure to aromatic and aliphatic hydrocarbons, which are the main constituents of JP-8 military aircraft jet fuel, occurred over 3-5 years\u27 duration while working on or near the flight line. Exposure to toxic hydrocarbons was substantiated by the presence of JP-8 metabolit
Prevalence and correlates of depressive disorders in people with Type 2 diabetes: results from the International Prevalence and Treatment of Diabetes and Depression (INTERPRET‐DD) study, a collaborative study carried out in 14 countries
Aims
To assess the prevalence and management of depressive disorders in people with Type 2 diabetes in different countries.
Methods
People with diabetes aged 18–65 years and treated in outpatient settings were recruited in 14 countries and underwent a psychiatric interview. Participants completed the Patient Health Questionnaire and the Problem Areas in Diabetes scale. Demographic and medical record data were collected.
Results
A total of 2783 people with Type 2 diabetes (45.3% men, mean duration of diabetes 8.8 years) participated. Overall, 10.6% were diagnosed with current major depressive disorder and 17.0% reported moderate to severe levels of depressive symptomatology (Patient Health Questionnaire scores >9). Multivariable analyses showed that, after controlling for country, current major depressive disorder was significantly associated with gender (women) (PPPPP<0.0001). The proportion of those with either current major depressive disorder or moderate to severe levels of depressive symptomatology who had a diagnosis or any treatment for their depression recorded in their medical records was extremely low and non-existent in many countries (0–29.6%).
Conclusions
Our international study, the largest of this type ever undertaken, shows that people with diabetes frequently have depressive disorders and also significant levels of depressive symptoms. Our findings indicate that the identification and appropriate care for psychological and psychiatric problems is not the norm and suggest a lack of the comprehensive approach to diabetes management that is needed to improve clinical outcomes
High-resolution climate change scenarios for India for the 21st century
A state-of-art regional climate modelling system, known as PRECIS (Providing Regional Climates for Impacts Studies) developed by the Hadley Centre for Climate Prediction and Research, is applied for India to develop high-resolution climate change scenarios. The presentday simulation (1961-1990) with PRECIS is evaluated, including an examination of the impact of enhanced resolution and an identification of biases. The RCM is able to resolve features on finer scales than those resolved by the GCM, particularly those related to improved resolution of the topography. The most notable advantage of using the RCM is a more realistic representation of the spatial patterns of summer monsoon rainfall such as the maximum along the windward side of the Western Ghats. There are notable quantitative biases in precipitation over some regions, mainly due to similar biases in the driving GCM. PRECIS simulations under scenarios of increasing greenhouse gas concentrations and sulphate aerosols indicate marked increase in both rainfall and temperature towards the end of the 21st century. Surface air temperature and rainfall show similar patterns of projected changes under A2 and B2 scenarios, but the B2 scenario shows slightly lower magnitudes of the projected change. The warming is monotonously widespread over the country, but there are substantial spatial differences in the projected rainfall changes. West central India shows maximum expected increase in rainfall. Extremes in maximum and minimum temperatures are also expected to increase into the future, but the night temperatures are increasing faster than the day temperatures. Extreme precipitation shows substantial increases over a large area, and particularly over the west coast of India and west central India
Replacing paper data collection forms with electronic data entry in the field: findings from a study of community-acquired bloodstream infections in Pemba Zanzibar
BackgroundEntering data on case report forms and subsequently digitizing them in electronic media is the traditional way to maintain a record keeping system in field studies. Direct data entry using an electronic device avoids this two-step process. It is gaining in popularity and has replaced the paper-based data entry system in many studies. We report our experiences with paper- and PDA-based data collection during a fever surveillance study in Pemba Island, Zanzibar, Tanzania.MethodsData were collected on a 14-page case report paper form in the first period of the study. The case report paper forms were then replaced with handheld computers (personal digital assistants or PDAs). The PDAs were used for screening and clinical data collection, including a rapid assessment of patient eligibility, real time errors, and inconsistency checking.ResultsA comparison of paper-based data collection with PDA data collection showed that direct data entry via PDA was faster and 25% cheaper. Data was more accurate (7% versus 1% erroneous data) and omission did not occur with electronic data collection. Delayed data turnaround times and late error detections in the paper-based system which made error corrections difficult were avoided using electronic data collection.ConclusionsElectronic data collection offers direct data entry at the initial point of contact. It has numerous advantages and has the potential to replace paper-based data collection in the field. The availability of information and communication technologies for direct data transfer has the potential to improve the conduct of public health research in resource-poor settings
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Factors associated with the onset of major depressive disorder in adults with type 2 diabetes living in 12 different countries: results from the INTERPRET-DD prospective study
Aims: To examine the factors that are associated with changes in depression in people with type 2 diabetes living in 12 different countries.
Methods: People with type 2 diabetes treated in out-patient settings aged 18-65 years underwent a psychiatric assessment to diagnose major depressive disorder (MDD) at baseline and follow-up. At both time points, participants completed the Patient Health Questionnaire (PHQ-9), the WHO five-item Well-being scale (WHO-5) and the Problem Areas in Diabetes (PAID) scale which measures diabetes-related distress. A composite stress score (CSS) (the occurrence of stressful life events and their reported degree of 'upset') between baseline and follow-up was calculated. Demographic data and medical record information were collected. Separate regression analyses were conducted with MDD and PHQ-9 scores as the dependent variables.
Results: In total, there were 7.4% (120) incident cases of MDD with 81.5% (1317) continuing to remain free of a diagnosis of MDD. Univariate analyses demonstrated that those with MDD were more likely to be female, less likely to be physically active, more likely to have diabetes complications at baseline and have higher CSS. Mean scores for the WHO-5, PAID and PHQ-9 were poorer in those with incident MDD compared with those who had never had a diagnosis of MDD. Regression analyses demonstrated that higher PHQ-9, lower WHO-5 scores and greater CSS were significant predictors of incident MDD. Significant predictors of PHQ-9 were baseline PHQ-9 score, WHO-5, PAID and CSS.
Conclusion: This study demonstrates the importance of psychosocial factors in addition to physiological variables in the development of depressive symptoms and incident MDD in people with type 2 diabetes. Stressful life events, depressive symptoms and diabetes-related distress all play a significant role which has implications for practice. A more holistic approach to care, which recognises the interplay of these psychosocial factors, may help to mitigate their impact on diabetes self-management as well as MDD, thus early screening and treatment for symptoms is recommended
Prevalence and correlates of depressive disorders in people with Type 2 diabetes: results from the international prevalence and treatment of diabetes and depression (INTERPRET-DD) study, a collaborative study carried out in 14 countries
AIMS:
To assess the prevalence and management of depressive disorders in people with Type 2 diabetes in different countries.
METHODS:
People with diabetes aged 18-65 years and treated in outpatient settings were recruited in 14 countries and underwent a psychiatric interview. Participants completed the Patient Health Questionnaire and the Problem Areas in Diabetes scale. Demographic and medical record data were collected.
RESULTS:
A total of 2783 people with Type 2 diabetes (45.3% men, mean duration of diabetes 8.8 years) participated. Overall, 10.6% were diagnosed with current major depressive disorder and 17.0% reported moderate to severe levels of depressive symptomatology (Patient Health Questionnaire scores >9). Multivariable analyses showed that, after controlling for country, current major depressive disorder was significantly associated with gender (women) (P<0.0001), a lower level of education (P<0.05), doing less exercise (P<0.01), higher levels of diabetes distress (P<0.0001) and a previous diagnosis of major depressive disorder (P<0.0001). The proportion of those with either current major depressive disorder or moderate to severe levels of depressive symptomatology who had a diagnosis or any treatment for their depression recorded in their medical records was extremely low and non-existent in many countries (0-29.6%).
CONCLUSIONS:
Our international study, the largest of this type ever undertaken, shows that people with diabetes frequently have depressive disorders and also significant levels of depressive symptoms. Our findings indicate that the identification and appropriate care for psychological and psychiatric problems is not the norm and suggest a lack of the comprehensive approach to diabetes management that is needed to improve clinical outcomes
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