Evaluation of Pica in Anemic Pregnancies

Amaç: Doğum öncesi bakım hizmeti almak için kadın hastalıkları ve doğumpolikliniğine başvuran, anemi tanısı almış gebelerde pika alışkanlığı sıklığınıbelirlemek amacıyla yapılmıştır.Materyal metod: Kadın hastalıkları ve doğum polikliniğine doğum öncesi bakımalmak için başvuran 2. ve 3. Trimestir gebeliği olan anemi tanısı almış veçalışmaya katılmayı kabul eden 203 gebeden oluşmaktadır.Bulgular: Araştırma kapsamında gebelerin %32’sinde (65) pika alışkanlığı olduğutespit edilmiş olup, gebelere besleyici değeri olmayan “ne yersiniz?” sorususoruluğunda gebelerin; 65’i (%100) buz, kâğıt ve toprak, 63’ü (96.9) boya, 4’ü(%2,6)saç yediklerini bildirmişlerdir.Sonuç: Çalışmamızda her üç anemik gebenin birinde pika alışkanlığı tespitedilmiştir. Bu anlamda doğum öncesi izlem sırasında gebelerin pikaalışkanlığının erken dönemde tespit edilip teratojenite açısından da gebelerintakibi ve bilgilendirmesi yapılmalıdır.Aim: This study was conducted to determine the frequency of pica habit in pregnant women who applied to obstetrics and gynecology outpatient clinic in order to receive prenatal care services and were diagnosed with anemia. Material and method: It includes 203 pregnant women who accepted to participate in the study, and who applied to Obstetrics and Gynecology outpatient clinic for prenatal care, were diagnosed with anemia and had 2nd and 3rd Trimester pregnancy. Findings: Within the scope of this study, it was determined that 32% (65) of pregnant women had pica habit. When the pregnant women were asked a question which had no nutritional values like, "What do you eat?", 65 (100%) of the patients reported that they ate ice, paper and soil, and 63 (96.9) and 4 (2.6%) of them reported that they ate dyes and hair, respectively. Result: Pica habit was detected in one of every three anemic pregnant women in our study. During prenatal follow-up, the pica habit of the pregnant women should be determined in the early period and they should be followed-up and informed in terms of teratogenicity

Endometrial Flushing Tumor Necrosis Factor Alpha and Interleukin 2 Levels in Women with Polycystic Ovary Syndrome, Leiomyoma and Endometrioma: Comparison with Healthy Controls

Introduction An important open question in the literature is whether endometrial receptivity marker levels are different in infertility related diseases than healthy women. The aim of the study is to compare the levels of interleukin two (IL-2) and tumor necrosis factor alpha (TNF-?) during the implantation window in the endometrial flushing fluid of polycystic ovary syndrome (PCOS), endometrioma, leiomyoma patients with healthy controls. Material and Methods In this case control study, after obtaining endometrial flushing fluids at mid-luteal phase of ovulatory women with PCOS (n = 20), endometrioma (n = 19), leiomyoma (n = 20) and healthy controls (n = 20), IL-2 and TNF-? levels were measured using ELISA kits in BioTek ELISA devices. Results Mean TNF-? levels (ng/mL) were similar for the PCOS (305.6, p = 0.220) and the leiomyoma group (246.3, p = 0.502) compared to healthy patients (261.1). However, the levels were higher in the endometrioma group (338.2, p = 0,004) than the control group (261.1) in a statistically significant way. Mean IL-2 levels (ng/mL) were significantly lower in the PCOS (290.9, p = 0.0005), the leiomyoma (282.9, p = 0.0002) and the endometrioma patients (229.5, p = 0.0009) than the control group (416.0). Conclusion Relative to the control group, endometrial flushing fluid TNF-? levels were significantly higher in endometrioma patients and IL-2 levels were significantly lower in PCOS, leiomyoma and endometrioma patients. In benign gynecological diseases, endometrial markers related to infertility seem to show differences in endometrial flushing fluid. Future studies might identify the reference values for these markers, and endometrial markers can be used to diagnose gynecologic disorders causing infertility

A Comparative Multicentric Study on Serosal and Endometrial Myomectomy During Cesarean Section: Surgical Outcomes

Tinelli, Andrea/0000-0001-8426-8490; GULER, OGUZ/0000-0001-7756-4267; erol, onur/0000-0002-7411-1200WOS: 000514513400001PubMed: 32064967Objective: This multi-center study aims to determine the efficiency and safety of endometrial myomectomy (EM) for the removal of uterine fibroids during cesarean section (CS). Methods: Retrospective review of 360 women diagnosed for fibroids during pregnancy. They all delivered by CS between 2014 and 2019. The study groups included 118 women who only underwent EM, 120 women who only had subserosal myomectomy by traditional technique and 122 women with fibroids who decided to avoid cesarean myomectomy, as control group. They were analyzed and compared the surgical outcomes. Results: The EM, subserosal myomectomy and control groups were statistically (p > 0.05) similar for to age, body mass index (BMI), gravidity, parity, gestational age at delivery, indications for CS, number of excised fibroids, size of the largest myoma. Postoperative hemoglobin values and ? (?) hemoglobin concentrations were lower in SM group (10.39gr/dl vs 9.98 gr/dl vs 10.19 - 1.44 gr/dl vs 1.90 gr/dl vs 1.35; p = 0.047, p = 0.021; respectively) Hybrid fibroids were significantly more frequent in the EM group than subserosal myomectomy and control groups (respectively, 33.1% vs 23.3% vs 27.0%, p = 0.002). Surgery time was significantly longer in the subserosal myomectomy group than EM and control groups (respectively, 46.53 min vs 37.88 min vs 33.86 min, p = 0.001). Myomectomy took significantly longer time in the subserosal myomectomy than EM group (13.75 min vs 8.17 min, p = 0.001). Conclusions: Endometrial myomectomy is a feasible choice for treatment of fibroids during CS, and, basing on our results could be an alternative to traditional cesarean subserosal myomectomy