The Relationship Between Myocardial Bridge and Electrocardiographic Tp-e Interval, Tp-e/QT and Tp-e/QTc Ratio

Aim: Myocardial bridge (MB) is generally known as an asymptomatic and benign anomaly, however, it can cause serious clinical conditions such as exercise-induced ventricular tachycardia and sudden death. Tp-e interval is the distance between the peak and the end of the T wave in electrocardiography. Tp-e/QT and Tp-e/QTc ratios are used as electrocardiographic indicators of ventricular arrhythmias. We have studied the effect of coronary angiographic features (the degree of stenosis and length of MB) of MB on myocardial repolarization parameters. Methods: The study group consisted of 53 patients with isolated MB and 58 patients with normal coronary arteries. Results: The QT interval and QTc were similar between the groups, however, Tp-e interval (92.72±14.72 and 79.59±12.12, respectively; p<0.001) and Tp-e/QT (0.24±0.041 and 0.21±0.025, respectively; p<0.001) and Tp-e/QTc (0.22±0.037 and 0.19±0.025, respectively; p<0.001) ratios were found to be significantly increased in MB group compared to the control group. In the comparison of the MB patients with critical and those with noncritical stenosis, Tp-e interval (100.69±10.79, 80.57±11.25, respectively; p<0.001) and Tp-e/QT (0.266±0.033, 0.219±0.037, respectively; p<0.001) and Tp-e/QTc (0.244±0.029, 0.196±0.027, respectively; p<0.001) ratios were higher in the MB with critical stenosis group. Conclusion: Our results indicate that these parameters can be practical ECG markers of ventricular arrhythmias in patients with MB

The implicit reaction function of the Central Bank of the Republic of Turkey

Reviewing the implicit reaction function estimation under different specifications, it appears that the Central Bank of the Republic of Turkey (CBRT) responds to the lagged inflation rate rather than the forward one, M2Y growth is targeted on an annual basis and a serious output targeting policy was implemented while neither real nor nominal depreciation of the foreign currency basket was taken into consideration during the period 1989:07-1997:03. Also, we conclude that the CBRT does not target currency issued, M2, net domestic assets or net foreign assets nor does it take any of the budget deficit measures into account while determining its monetary policy.

Bilirubin levels and thrombus burden in patients with ST-segment elevation myocardial infarction

duman, hakan/0000-0002-1441-7320WOS: 000377215900010PubMed: 26339042We investigated whether serum bilirubin level (a marker of heme oxygenase activity) is a predictor of thrombus burden in patients with acute myocardial infarction. Patients (n = 229; male 72.9%; mean age 63 +/- 13.4 years) who were admitted with ST-segment elevation myocardial infarction (STEMI) were enrolled. Patients were divided into 2 groups. Group 1 was defined as low thrombus burden and group 2 was defined as high thrombus burden. Patients with high thrombus burden had higher total bilirubin levels (14.4 [4.3-22.9] vs 7.7 [2.4-20.3] mu mol/L, P .001), (0.84 [0.25-1.34] vs 0.45 [0.14-1.19] mg/dL P .001) and direct bilirubin levels (3.1 [2.1-8.4] vs 1.7 [0.5-6.5] mu mol/L, P .001), (0.18 [0.03-0.49] vs 0.10 [0.03-0.38] mg/dL, P .001). At multivariate analysis, total bilirubin (odds ratio: 1.05, 95% confidence interval: 1.03-1.08, P .001) was the independent predictor of high thrombus burden. in conclusion, total bilirubin level is independently associated with high thrombus burden in patients with STEMI

Plateletkrit ve Trombosit Dağılım Genişliği Koroner Arter Ektazisinin Bağımsız Öngördürücüsüdür

Giriş: Koroner arter ektazisi (KAE), koroner arterlerin anormal genişlemesi ile karakterize edilir. Ortalama trombosit hacmi (OTH), trombosit dağılım genişliği (TDG), plateletkrit (PKT) dahil olmak üzere trombosit hacmi endeksleri ve trombosit sayısı trombosit aktivasyonunun göstergeleridir. Bu çalışmada KAE'li hastalarda trombosit hacmi endeksleri incelendi. Hastalar ve Yöntem: Çalışmaya, izole KAE'si olan 51 (38 erkek; ortalama yaş: 52 + 9.9 yıl) hasta ve koroner arterleri normal olan 50 (39 erkek; ortalama yaş: 54 + 11.3 yıl) sağlıklı birey dahil edildi. Başvuruda trombosit hacmi endeksleri otomatik tam kan sayımı parçası olarak ölçüldü. Bulgular: Trombosit sayımı, OTH, PKT ve TDG, KAE grubunda kontrol grubuna göre daha yüksekti (p<0.05). Çok değişkenli lojistik regresyon analizinde, TDG (Odds oranı: 0.22, %95 güven aralığı: 0.06-0.73,p= 0.013) ve PKT'nin (Odds oranı: 3.41, %95 güven aralığı: 1.66-6.98, p<= 0.001) KAE'nin bağımsız öngördürücüleri olduğu gösterildi. Sonuç: Bu çalışma, PKT ve TDG'nin KAE'nin bağımsız belirleyicileri olduğunu göstermektedir.Introduction: Coronary artery ectasia (CAE) is characterised by an abnormal dilatation of the coronary arteries. Platelet volume indices, including the mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT) and platelet count, are indicators of platelet activation. In this study, we investigated platelet volume indices in patients with CAE. Patients and Methods: The study group included 51 patients (38 men; mean age: 52 ± 9.9 years) with isolated CAE and 50 individuals with normal coronary arteries (39 men; mean age: 54 ± 11.3 years). Admission platelet volume indices were measured as part of the automated complete blood count. Results: Platelet count, MPV, PCT and PDW were higher in CAE than in the control group (p< 0.05). Multivariate analysis revealed PDW (odds ratio: 0.22, 95% confidence interval: 0.06-0.73, p= 0.013) and PCT (odds ratio: 3.41, 95% confidence interval: 1.66-6.98, p<= 0.001) as independent predictors of CAE. Conclusion: This study demonstrates that PCT and PDW are independent predictors of CAE