Generalized Matsui Algorithm 1 with application for the full DES

In this paper we introduce the strictly zero-correlation attack. We extend the work of Ashur and Posteuca in BalkanCryptSec 2018 and build a 0-correlation key-dependent linear trails covering the full DES. We show how this approximation can be used for a key recovery attack and empirically verify our claims through a series of experiments. To the best of our knowledge, this paper is the first to use this kind of property to leverage a meaningful attack against a symmetric-key algorithm

Non-Negative Matrix Factorization for Learning Alignment-Specific Models of Protein Evolution

Models of protein evolution currently come in two flavors: generalist and specialist. Generalist models (e.g. PAM, JTT, WAG) adopt a one-size-fits-all approach, where a single model is estimated from a number of different protein alignments. Specialist models (e.g. mtREV, rtREV, HIVbetween) can be estimated when a large quantity of data are available for a single organism or gene, and are intended for use on that organism or gene only. Unsurprisingly, specialist models outperform generalist models, but in most instances there simply are not enough data available to estimate them. We propose a method for estimating alignment-specific models of protein evolution in which the complexity of the model is adapted to suit the richness of the data. Our method uses non-negative matrix factorization (NNMF) to learn a set of basis matrices from a general dataset containing a large number of alignments of different proteins, thus capturing the dimensions of important variation. It then learns a set of weights that are specific to the organism or gene of interest and for which only a smaller dataset is available. Thus the alignment-specific model is obtained as a weighted sum of the basis matrices. Having been constrained to vary along only as many dimensions as the data justify, the model has far fewer parameters than would be required to estimate a specialist model. We show that our NNMF procedure produces models that outperform existing methods on all but one of 50 test alignments. The basis matrices we obtain confirm the expectation that amino acid properties tend to be conserved, and allow us to quantify, on specific alignments, how the strength of conservation varies across different properties. We also apply our new models to phylogeny inference and show that the resulting phylogenies are different from, and have improved likelihood over, those inferred under standard models

Non-repudiable authentication and billing architecture for wireless mesh networks

The original publication is available at www.springerlink.comWireless mesh networks (WMNs) are a kind of wireless ad hoc networks that are multi-hop where packets are forwarded from source to destination by intermediate notes as well as routers that form a kind of network infrastructure backbone. We investigate the security of the recently proposed first known secure authentication and billing architecture for WMNs which eliminates the need for bilateral roaming agreements and that for traditional home-foreign domains. We show that this architecture does not securely provide incontestable billing contrary to designer claims and furthermore it does not achieve entity authentication. We then present an enhanced scheme that achieves entity authentication and nonrepudiable billing

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

Accounting for Unemployment--A Labour Market Perspective.

The author examines whether prolonged high unemployment in Canada can be attributed to various "structural" causes, rather than t o demand deficiency as found by macroeconometric models. The answer i s largely negative. Neither the dispersion of sectoral growth rates n or excessive and rigid real wages can convincingly account for most u nemployment. Contentions to the contrary are based upon inappropriate partial analyses. Enduring shifts in industrial structure have, if a nything, been declining. Labor mobility is high. Much unemployment la sts too long to be frictional. Fuller quantitative understanding of t he nature of unemployment can be achieved only in a more general fram ework.