Prophylactic amnioinfusion in oligohydramnios

Background: Oligohydramnios causes many intrapartum maternal and fetal complications. Intrapartum amnioinfusion effectively increases amniotic fluid volume and thereby decreases FH decelerations. The objective of this study was to compare the frequency of fetal heart decelerations and its perinatal outcome with and without amnioinfusion in patients with oligohydramnios and the cesarean rates for fetal distress between them.Methods: In study group, 100 patients in labour with AFI < 5 cm, oligohydramnios and IUGR with normal doppler, postdated pregnancies with AFI ≤ 5 cm with normal doppler were selected and prophylactic amnioinfusion with 300 ml lukewarm saline is given aseptically for 15 minutes after amniotomy. Continuous CTG monitoring done till delivery. If FH decelerations occur, the bolus was repeated up to 3 times. 100 age matched controls managed with conventional methods without amnioinfusion were selected retrospectively from labour room case records.Results: Incidence of FH decelerations was lower in study group (59% versus 84%). Cesarean section for fetal distress was reduced (20.9% versus 79.1%) Perinatal outcome was better. Babies with normal 1-minute Apgar was 86% compared to 75% in controls. Frequency of FH decelerations was reduced (20% versus 73%). Occurrence of 2 FH decelerations were 13% versus 33%, 3 FH decelerations were 7% versus 27% and > 3 times was 0% versus 13%.Conclusions: Prophylactic amnioinfusion can easily and effectively reduce the FH decelerations and caesarean section rate for fetal distress in oligohydramnios improving both maternal and fetal outcomes with negligible risks

HPV-Reactive T-Cell Receptor Expand in Combination Therapy

https://openworks.mdanderson.org/sumexp22/1001/thumbnail.jp

A Cryptographic Algorithm using Fuzzy Logic and Deck of Cards

Sharing of information in a secured manner is extremely essential in this world of internet technology. In recent times, many people come across situations wherein their personal data are being hacked by trespassers. These stolen data are used for many malpractices including theft of money. Many researchers involve themselves in finding a better path to overcome this difficulty. Cryptography plays a major role in bringing out a solution to rectify this issue. Mathematics provides a helping hand in most of the cryptographic techniques. It helps to secure data from hackers involved in the robbery of data. Fuzzy logic find its application in many field of research. This paper proposes a cryptographic technique which make use of fuzzy logic together with the help of deck of cards and its membership functional value

Web Platform for Interconnecting Body Sensors and Improving Health Care

The Internet of Things (IoT) is a paradigm in which smart objects actively collaborate among them and with other physical and virtual objects available in the Web in order to perform high-level tasks for the benefit of end-users. In the e-health scenario, these communicating smart objects can be body sensors that enable a continuous real-time monitoring of vital signs of patients. Data produced by such sensors can be used for several purposes and by different actors, such as doctors, patients, relatives, and health care centers, in order to provide remote assistance to users. However, major challenges arise mainly in terms of the interoperabil- ity among several heterogeneous devices from a variety of manufacturers. In this context, we introduce Eco Health (Ecosystem of Health Care Devices), a Web middleware platform for connecting doctors and patients using attached body sensors, thus aiming to provide improved health monitoring and diagnosis for patients. This platform is able to integrate information obtained from heterogeneous sensors in order to provide mechanisms to monitor, process, visualize, store, and send notifications regarding patients’ conditions and vital signs at real-time by using Internet standards. In this paper, we present blueprints of our proposal to Eco Health and its logical architecture and implementation, as well as an e-health motivational scenario where such a platform would be useful

An Efficient Cost Estimation Model with Fuzzy Expert System

In this paper we are proposing fault prediction based cost effective analysis over source code, we register the measurements over deficiency inclined modules and contrast and past methodology issue inclined, for each test approach we process measurements and advances to fuzzy master framework and contrast and past form. Our proposed approach gives more productive results than conventional methodology. The need of conveyed and complex business applications in big business requests fault free and quality application frameworks. This makes it critical in software advancement to create quality and fault free software. It is likewise critical to plan solid and simple to keep up as it includes a considerable measure of human endeavors, cost and time amid software life cycle. A product advancement process performs different exercises to minimize the shortcomings, for example, flaw forecast, location, avoidance and remedy. This paper exhibits an overview on current practices for software issue location and counteractive action components in the product improvement. It additionally talks about the preferences and confinements of these instruments which identifies with the quality item improvement and support. As of not long ago, different strategies have been proposed for anticipating flaw inclined modules in light of expectation execution. Sadly quality change and cost lessening has been once in a while surveyed. The fundamental inspiration here is improvement of acknowledgment testing to give fantastic administrations to clients

Assessing the potential for crop albedo enhancement in reducing heatwave frequency, duration, and intensity under future climate change

Adapting to the impacts of future warming, and in particular the impacts of heatwaves, is an increasingly important challenge. One proposed strategy is land-surface radiation management via crop albedo enhancement. This has been argued to be an effective method of reducing daily hot temperature extremes regionally. However, the influence of crop albedo enhancement on heatwave events, which last three or more days, is yet to be explored and this remains an important knowledge gap. Using a fully coupled earth system model with 10 ensemble members, we show that crop albedo enhancement by up to ＋0.1 reduces the frequency of heatwave days over Europe and North America by 10 to 20 days; with a larger reduction over Europe under a future climate driven by SSP2-4.5. The average temperature anomaly during heatwaves (the magnitude of the event), is reduced by 0.8 °C to 1.2 °C where the albedo was enhanced, but reductions in mean heatwave duration are limited. There was a marked reduction in the mean annual cumulative heatwave intensity across most of Eurasia and North America, ranging from 32 °C to as high as 80 °C in parts of southern Europe. These changes were largely driven by a reduction in net radiation, decreasing the sensible heat flux, which reduces the maximum temperature, and therefore, heatwave frequency and intensity. These changes were largely localised to where the albedo enhancement was applied with no significant changes in atmospheric circulation or precipitation, which presents advantages for implementation. While our albedo perturbation of up to ＋0.1 is large and represents the likely upper limit of what is possible with more reflective crops, and we assume that more reflective crops are grown everywhere and instantly, these results provide useful guidance to policy makers and farmers on the maximum possible benefits of using more reflective crops in limiting the impacts of heatwaves under future climate

Malignant mandibular tumors: two case reports of rare mandibular tumors in a single institution

Mandibular lesions can be benign or malignant, malignant being less common. The most common malignant tumor of mandible is squamous cell carcinoma. Others are ameloblastic carcinoma,  osteosarcoma, chondrosarcoma, fibrosarcoma, malignant fibrous histiocytoma and metastasis. Osteosarcoma is a bone tumor. It can occur in any bone, usually in the long bones of the extremities, but osteosarcoma of mandible is rare. In the initial phase, they may present as nondescript bony swellings with an indolent growth, only to become malignant towards the later stages. Osteosarcomas of the jaw are rare and they differ from osteosarcomas of the long bones in their biological behavior, even though they have the same histological appearance. Malignant fibrous histiocytoma (MFH) is the most common soft-­‐tissue sarcoma, but  relatively uncommon in head and neck region with only 30 reported cases till date. The purpose of this report is to present two cases of rare malignant mandibular tumors in a single institution.KEY WORDS: Osteosarcoma; Malignant fibrous histiocytoma; Mandibl

Characterization of Chemical Compounds in Volatile Oil and Ethyl Acetate Extract of Lavandula angustifolia by GC-MS

Lavandula angustifolia is an important aromatic plant and rich source of linalool. L. angustifolia and its bioactive compounds have been reported to possess several bioactivities such as antioxidant, antifungal, antibacterial and antidiabetic etc. The aim of the present study is to characterize chemical compounds present in volatile oil and ethyl acetate extract of L. angustifolia aerial parts by gas chromatography mass spectroscopy (GC-MS). The hydrodistillation of aerial parts of L. angustifolia yielded 1.56±0.27% v/w volatile oil. The GC-MS analysis of volatile oil of L. angustifolia yielded 74 chemical compounds, and lavandulyl isobutyrate (52.61%), and linalool (5.41%) were identified as major compounds. Ultrasonication was utilized for extraction of L. angustifolia using ethyl acetate as solvent and extraction yield was found to be 3.59±0.73% w/w. The GC-MS analysis of ethyl acetate extract of L. angustifolia yielded 40 chemical compounds and the major compounds were dotriacontane (8.33%), linalool (7.09%), eucalyptol (6.42%), linalyl acetate (4.69%), 1,4-cineole (4.62%), and trans-linalool oxide (4.51%). The present study explores the chemical composition of volatile oil and ethyl acetate extract of L. angustifolia

Comparative epidemiology and factors associated with major healthcare-associated methicillin-resistant Staphylococcus aureus clones among interconnected acute-, intermediate- and long-term healthcare facilities in Singapore

Funding: Bioinformatics and Computational Biology analyses were supported by the University of St Andrews Bioinformatics Unit that is funded by a Wellcome Trust ISSF award (grant 097831/Z/11/Z). M.T.G.H is supported by the Scottish Infection Research Network and Chief Scientist Office through the Scottish Healthcare Associated Infection Prevention Institute consortium funding (CSO Reference: SIRN10).Objectives Methicillin-resistant Staphylococcus aureus(MRSA) has spread across countries and healthcare settings, with different ecological niches for different clones. It is crucial to understand the comparative epidemiology of MRSA clones between healthcare settings, and independent factors associated with colonization of specific clones. Methods We conducted annual cross-sectional surveillance studies in a network comprising an acute-care hospital and six closely-affiliated intermediate- and long-term care facilities in Singapore, in June-July, 2014-2016. 5,394 patients contributed 16,045 nasal, axillary and groin samples for culture and MRSA isolates for whole genome sequencing. Multivariable multilevel multinomial regression models were constructed to assess for independent factors associated with MRSA colonization. Results MRSA clonal complex(CC) 22 was more prevalent in the acute-care hospital(n=256/493; 51.9%) and intermediate-care(n=348/634; 54.9%) than long-term care(n=88/351; 25.1%) facilities, with clones besides CC22 and CC45 being more prevalent in long-term care facilities(n=144/351; 41.0%) (P<0.001). Groin colonization with CC45 was 6 times that of nasal colonization(aOR 6.21, 95%CI 4.26-9.01). Prior MRSA carriage was associated with increased odds of current MRSA colonization in all settings, with a stronger association with CC22(aOR 6.45, 95%CI 3.85-10.87) than CC45(aOR 4.15, 95%CI 2.26-7.58). Conclusions Colonization of MRSA clones differed between anatomic sites and across healthcare settings. With CC22 having a predilection for the nares and CC45 the groin, MRSA screening should include both sites. Prior MRSA carriage is a risk factor for colonization with predominant MRSA clones in the acute-care hospital and intermediate- and long-term care facilities. Contact precautions for prior MRSA-carriers on admission to any healthcare facility could prevent intra- and inter-institutional MRSA transmission.PostprintPeer reviewe

Design of DC Wirings for urban house in Indonesia including analysis on appliances, power losses, and costs: An alternative to Support Rooftop PV Uptake

Most of the application of solar PV in Indonesia uses inverter, which is a complex and expensive electronics system. Many of the PV plants are in fault condition due to the failure of the inverter. This paper proposed DC wirings powered by solar PV for houses in the urban area of Indonesia. First, the paper reviewed the availability of electrical appliances powered by DC voltage supply. Secondly, it presents AC and DC house wiring designs for a house with 1 300 VA electrical power limit. Losses of both wirings are analyzed and compared, including the cost of wirings materials. The survey showed appliances such as air conditioning, fridgefreezer, television, washing machine, and other appliances are now available in DC voltage supply. A 48 V DC bus is chosen to minimize losses. From a cost perspective, AC and DC wiring systems are comparable, but the DC house is slightly more expensive due to the cost of appliances. The cost of DC wirings is lower due to the lower cost of the DC-DC converters and uses fewer conductors. The results provide an alternative to using solar PV directly distributed as DC voltage for the houses in the urban area of the country