Gauged Discrete Symmetries and Proton Stability

We discuss the results of a search for anomaly free Abelian Z_N discrete symmetries that lead to automatic R-parity conservation and prevents dangerous higher-dimensional proton decay operators in simple extensions of the minimal supersymmetric extension of the standard model (MSSM) based on the left-right symmetric group, the Pati-Salam group and SO(10). We require that the superpotential for the models have enough structures to be able to give correct symmetry breaking to MSSM and potentially realistic fermion masses. We find viable models in each of the extensions and for all the cases, anomaly freedom of the discrete symmetry restricts the number of generations.Comment: 8 pages, 2 figures; v2 : typos fixed, references adde

In-water lidar simulations: the ALADIN ADM-Aeolus backscattered signal at 355 nm

The Lidar Ocean Color (LiOC) Monte Carlo code has been developed to simulate the in-water propagation of the lidar beam emitted by the ALADIN ADM-Aeolus instrument in the ultraviolet (UV) spectral region (∼ 355 nm). To this end, LiOC accounts for reflection/transmission processes at the sea surface, absorption and multiple scattering in the water volume, and reflection from the sea bottom. The water volume components included in the model are pure seawater, Chlorophyll-a concentration (Chl-a), Colored Dissolved Organic Matter (CDOM), and/or a generic absorbing species. By considering the transmission/reception measurement geometry of ALADIN ADM-Aeolus, the study documents the variability of the normalized backscattered signal in different bio-optical conditions. The potential for data product retrieval based on information at 355 nm is considered by developing a demonstrative lookup table to estimate the absorption budget exceeding that explained by Chl-a. Results acknowledge the interest of space programs in exploiting UV bands for ocean color remote sensing, as, for instance, addressed by the PACE mission of NASA

Direct and Indirect Detection of Dark Matter in D6 Flavor Symmetric Model

We study a fermionic dark matter in a non-supersymmetric extension of the standard model with a family symmetry based on D6xZ2xZ2. In our model, the final state of the dark matter annihilation is determined to be e+ e- by the flavor symmetry, which is consistent with the PAMELA result. At first, we show that our dark matter mass should be within the range of 230 GeV - 750 GeV in the WMAP analysis combined with mu to e gamma constraint. Moreover we simultaneously explain the experiments of direct and indirect detection, by simply adding a gauge and D6 singlet real scalar field. In the direct detection experiments, we show that the lighter dark matter mass ~ 230 GeV and the lighter standard model Higgs boson ~ 115 GeV is in favor of the observed bounds reported by CDMS II and XENON100. In the indirect detection experiments, we explain the positron excess reported by PAMELA through the Breit-Wigner enhancement mechanism. We also show that our model is consistent with no antiproton excess suggested by PAMELA.Comment: 20 pages, 9 figures, 2 tables, accepted version for publication in European Physical Journal

Video Capsule Retention in a Zenker Diverticulum

We report the case of a video capsule endoscope lodged within a Zenker diverticulum. The system that was equipped with a real-time viewer showed an unchanging image unlike esophageal or gastric mucosa, suggesting that the capsule was elsewhere. The presence of cervical discomfort suggested video capsule retention in a Zenker diverticulum. The capsule was removed endoscopically and reinserted using a hood-assisted endoscope and the procedure was completed

Exploring the potential of Aeolus lidar mission for ocean color applications

The Atmospheric Laser Doppler Instrument (ALADIN) onboard the Aeolus wind mission was the first High Spectral Resolution Lidar operating in the Ultra Violet (UV) region deployed in space. This study explores and documents the feasibility of deriving ocean optical properties using data from ALADIN. A three steps (i.e. data screening, analytical estimation of the total in-water signal contribution, Look Up Table-based estimation of the in-water attenuation) retrieval algorithm was developped combining data analysis and signal simulations from a radiative transfer model. The algorithm has been implemented using the signal acquired by the Mie channel, and tested for 1-year of Aeolus observations. This approach allowed estimating the first Aeolus derived Ocean Color (OC) products in terms of the total in-water signal contribution and the in-water attenuation term in a spectral region (355 nm) not covered, during Aeolous lifetime, by operational OC products. The validation process involved comparing these products with both Biogeochemical-Argo (BGC-Argo) field measurements and satellite OC dataset distributed by ESA Ocean Color Climate Change Initiative across a set of 7 selected oceanic regions representing diverse open-ocean scenarios. These validation exercises attested the general accordance between OC reference measurements and the proposed Aeolus OC parameters. Thus, this study was able to provide statistical evidence of the sensitivity of the retrieved Aeolus in-water lidar attenuation term to the CDOM variability on a temporal/seasonal and spatial/regional basis. A preliminary estimation of the uncertainty associated to the retrieved quality controlled Klid, was performed assuming the radiometric noise as unique source of uncertainty. As a result, a median/average value of absolute relative percent difference of about 50/80% was obtained. Limits of the developed technique, possible improvements, potential adaptation to planned/future space lidar missions are discussed

Strain Relaxation Mechanisms and Local Structural Changes in Si_{1-x}$Ge_{x} Alloys

In this work, we address issues pertinent to the understanding of the structural and electronic properties of Si_{1-x} Ge_{x}alloys, namely, (i) how does the lattice constant mismatch between bulk Si and bulk Ge manifests itself in the alloy system? and (ii) what are the relevant strain release mechanisms? To provide answers to these questions, we have carried out an in-depth study of the changes in the local geometric and electronic structures arising from the strain relaxation in Si_{1-x} Ge_{x} alloys using an ab initio molecular dynamics scheme. The optimized lattice constant, while exhibiting a general trend of linear dependence on the composition (Vegard's law), shows a negative deviation from Vegard's law in the vicinity of x=0.5. We delineate the mechanisms responsible for each one of the above features. We show that the radial-strain relaxation through bond stretching is responsible for the overall trend of linear dependence of the lattice constant on the composition. On the other hand, the negative deviation from Vegard's law is shown to arise from the angular-strain relaxation.Comment: 21 pages, 7 figure

Inhibition of APN/CD13 leads to suppressed progressive potential in ovarian carcinoma cells

<p>Abstract</p> <p>Background</p> <p>Aminopeptidase N (APN/CD13), a 150-kDa metalloprotease, is a multifunctional cell surface aminopeptidase with ubiquitous expression. Recent studies have suggested that APN/CD13 plays an important role in tumor progression of several human malignancies. In the current study, we investigated the role of APN/CD13 in ovarian carcinoma (OVCA) progression.</p> <p>Methods</p> <p>We first examined the expression of APN/CD13 at the protein level in a variety of OVCA cell lines and tissues. We subsequently investigated whether there was a correlation between APN/CD13 expression and invasive potential of various OVCA cell lines. Moreover, we investigated the function of APN/CD13 in OVCA cells using bestatin, an APN/CD13 inhibitor, or transfection of siRNA for APN/CD13.</p> <p>Results</p> <p>We confirmed that APN/CD13 was expressed in OVCA tissues and cell lines to various extents. There was a positive correlation between APN/CD13 expression and migratory potential in various OVCA cell lines with accordingly enhanced secretion of endogenous MMP-2. Subsequently, we found a significant decrease in the proliferative and migratory abilities of OVCA cells after the addition of bestatin or the inhibition of APN/CD13 expression by siRNA. Furthermore, in an animal model, daily intraperitoneal administration of bestatin after inoculation of OVCA cells resulted in a decrease of peritoneal dissemination and in prolonged survival of nude mice.</p> <p>Conclusion</p> <p>The current data indicate the possible involvement of APN/CD13 in the development of OVCA, and suggest that clinical use of bestatin may contribute to better prognosis for ovarian carcinoma patients.</p

Repressing Anarchy in Neutrino Mass Textures

The recent results that $\theta_{13}$ is relatively large, of the order of the previous upper bound, and the indications of a sizable deviation of $\theta_{23}$ from the maximal value are in agreement with the predictions of Anarchy in the lepton sector. The quark and charged lepton hierarchies can then be reproduced in a SU(5) GUT context by attributing non-vanishing $U(1)_{FN}$ charges, different for each family, only to the SU(5) tenplet states. The fact that the observed mass hierarchies are stronger for up quarks than for down quarks and charged leptons supports this idea. As discussed in the past, in the flexible context of $SU(5)\otimes U(1)_{FN}$, different patterns of charges can be adopted going from Anarchy to various types of hierarchy. We revisit this approach by also considering new models and we compare all versions to the present data. As a result we confirm that, by relaxing the extreme ansatz of equal $U(1)_{FN}$ charges for all SU(5) pentaplets and singlets, better agreement with the data than for Anarchy is obtained without increasing the model complexity. We also present the distributions obtained in the different models for the Dirac CP-violating phase. Finally we discuss the relative merits of these simple models.Comment: v1: 12 pages, 3 figures; v2: 13 pages, 3 figures, text improved, matches version accepted for publication; v3: submitted to add an acknowledgment to a networ

Constraints from Solar and Reactor Neutrinos on Unparticle Long-Range Forces

We have investigated the impact of long-range forces induced by unparticle operators of scalar, vector and tensor nature coupled to fermions in the interpretation of solar neutrinos and KamLAND data. If the unparticle couplings to the neutrinos are mildly non-universal, such long-range forces will not factorize out in the neutrino flavour evolution. As a consequence large deviations from the observed standard matter-induced oscillation pattern for solar neutrinos would be generated. In this case, severe limits can be set on the infrared fix point scale, Lambda_u, and the new physics scale, M, as a function of the ultraviolet (d_UV) and anomalous (d) dimension of the unparticle operator. For a scalar unparticle, for instance, assuming the non-universality of the lepton couplings to unparticles to be of the order of a few per mil we find that, for d_UV=3 and d=1.1, M is constrained to be M > O(10^9) TeV (M > O(10^10) TeV) if Lambda_u= 1 TeV (10 TeV). For given values of Lambda_u and d, the corresponding bounds on M for vector [tensor] unparticles are approximately 100 [3/Sqrt(Lambda_u/TeV)] times those for the scalar case. Conversely, these results can be translated into severe constraints on universality violation of the fermion couplings to unparticle operators with scales which can be accessible at future colliders.Comment: 13 pages, 3 figures. Minor changes due to precision in numerical factors and correction in figure labels. References added. Conclusions remain unchange

Dark Matter from Minimal Flavor Violation

We consider theories of flavored dark matter, in which the dark matter particle is part of a multiplet transforming nontrivially under the flavor group of the Standard Model in a manner consistent with the principle of Minimal Flavor Violation (MFV). MFV automatically leads to the stability of the lightest state for a large number of flavor multiplets. If neutral, this particle is an excellent dark matter candidate. Furthermore, MFV implies specific patterns of mass splittings among the flavors of dark matter and governs the structure of the couplings between dark matter and ordinary particles, leading to a rich and predictive cosmology and phenomenology. We present an illustrative phenomenological study of an effective theory of a flavor SU(3)_Q triplet, gauge singlet scalar.Comment: 10 pages, 2 figures; v2: references added, minor changes to collider analysis, conclusions unchange