A fully CMOS true random number generator based on hidden attractor hyperchaotic system

Low-power devices used in Internet-of-things networks have been short of security due to the high power consumption of random number generators. This paper presents a low-power hyperchaos-based true random number generator, which is highly recommended for secure communications. The proposed system, which is based on a four-dimensional chaotic system with hidden attractors and oscillators, exhibits rich dynamics. Numerical analysis is provided to verify the dynamic characteristics of the proposed system. A fully customized circuit is deployed using 130 nm CMOS technology to enable integration into low-power devices. Four output signals are used to seed a SHIFT-XOR-based chaotic data post-processing to generate random bit output. The chip prototype was simulated and tested at 100 MHz sampling frequency. The hyperchaotic circuit consumes a maximum of 980 μ W in generating chaotic signals while dissipates a static current of 623 μ A. Moreover, the proposed system provides ready-to-use binary random bit sequences which have passed the well-known statistical randomness test suite NIST SP800-22. The proposed novel system design and its circuit implementation provide a best energy efficiency of 4.37 pJ/b at a maximum sampling frequency of 100 MHz

On the performance of multihop-intervehicular communications systems over n*Rayleigh fading channels

We investigate the performance of multihop-intervehicular communication systems with regenerative and nonregenerative relaying. We consider the so-called "n*Rayleigh distribution" as an adequate multipath fading channel model for vehicle-to-vehicle communication scenarios. We derive a novel approximation for the outage probability of maximum ratio combining (MRC) diversity reception. In addition, we analyze the amount of fading and optimize the power allocation for the investigated scenario. Numerical results show that regenerative systems are more efficient than nonregenerative systems when the cascading order (n) is small; however, for large n, our results demonstrate that the performance of both relaying techniques is rather similar.Comment: 4 pages, 5 figure

Half dose sugammadex combined with neostigmine is non-inferior to full dose sugammadex for reversal of rocuronium-induced deep neuromuscular blockade: a cost-saving strategy

Abstract Background Sugammadex reverses the effect of rocuronium more rapidly and effectively than neostigmine, at all levels of neuromuscular blockade (NMB). However, its cost is prohibitive. The combination of half dose sugammadex with neostigmine would be non-inferior to full dose sugammadex for the reversal of deep NMB. This approach would reduce the cost of sugammadex while preserving its efficacy. Methods Patients were randomly allocated to receive sugammadex 4 mg/kg (Group S) or sugammadex 2 mg/kg with neostigmine 50 μg/kg and glycopyrrolate 10 μg/kg (Group NS) for reversal of rocuronium deep NMB. The primary outcome was the percentage of patients who recovered to 90% Train of Four (TOF) ratio within 5 min. The non-inferiority margin was set at 10%. Results Twenty eight patients were enrolled in each group. The number of patients who reached 90% TOF ratio within 5 min was 27 out of 28 (96%) in group S versus 25 out of 28 (89%) in group NS by intention-to-treat (difference: 7%, 95% CI of the difference: −9% to 24%). The number of patients who reached 90% TOF ratio within 5 min was 26 out of 26 (100%) in group S versus 23 out of 25 (92%) in group NS by per-protocol (difference: 8%, 95% CI of the difference: −6% to 25%). Conclusions Sugammadex 2 mg/kg with neostigmine 50 μg/kg was at worst 9% and 6% less effective than sugammadex 4 mg/kg by intention-to-treat and by per-protocol analysis respectively. Hence, the combination is non-inferior to the recommended dose of sugammadex. Trial registration Clinicaltrials.gov NCT 02375217 , registered on February 11, 201

Intercept probability analysis over the cascaded Fisher-Snedecor ℱ fading wiretap channels

Abstract In this paper, we have investigated the physical layer security over cascaded Fisher-Snedecor ℱ fading channels in the presence of randomly distributed eavesdroppers. To characterize the eavesdroppers’ intercept capability, both the conceptual k-th nearest and best eavesdroppers are introduced. The probability density function (PDF) of the k-th nearest and best eavesdropper is characterized. The probability of interception, is correspondingly regarded as the secrecy metric, and is further derived with closed-form expressions in terms of Fox’s H-function. For the purposes of providing more insights, the asymptotic behavior of the intercept probability is also provided. To explore the effects of the eavesdroppers’ density and the channel fading conditions on the secrecy performance, we have performed the Monte-Carlo simulation and compared our analytical results with the simulated ones. One can find that our analytical results are successfully verified by the simulation results

End-Tidal CO

This prospective study included 32 patients undergoing cardiopulmonary bypass (CPB) for elective coronary artery bypass grafting correlates the respiratory end-tidal CO2 (ETCO2) during partial separation from CPB with cardiac output (CO) following weaning from CPB. After induction of general anesthesia, a pulmonary artery catheter was inserted for measurement of cardiac output by thermodilution. Patients were monitored using a 5-lead ECG, pulse oximeter, invasive blood pressure monitoring, rectal temperature probe, and end-tidal capnography. At the end of surgery, patients were weaned from CPB in a stepwise fashion. Respiratory ETCO2 and in-line venous oximetry were continuously monitored during weaning. The ETCO2 was recorded at quarter pump flow and after complete weaning from CPB. Following weaning from CPB, CO was measured by thermodilution. The CO values were correlated with the ETCO2 during partial bypass and following weaning from bypass. Regression analysis of ETCO2 at quarter-flow and post-bypass CO showed significant correlation (r = 0.57, p 30 mm Hg during partial CPB will always predict an adequate CO following weaning from CPB. An ETCO2 <30 mm Hg may denote either a low or a normal cardiac output and hence other predictive parameters such as SvO2 must be added