Cycling Past 50: A Closer Look into the World of Older Cyclists, Year 4 Survey

This document reports on approximately 5,000 responses to a North American survey of older adults who cycle. The survey, open from August 2021 through March 2022, included questions that captured a person’s cycling over their life course, as well as their current cycling styles, habits, and preferences. Responses reflect the impact of various factors on an older adult’s cycling habits with respect to their ability and agility and their expectation to continue cycling. The survey asked about falls and near misses in the past-year coding fall descriptions into six categories and sorting them by the respondent’s gender and age. The survey’s Visual Preference questions offered photos of cycling contexts and asked respondents to select four to six options for traveling within each context, then scored its safety and comfort level between 1 and 5. Key takeaways include: many older adults can continue to cycle as they age by using a different bicycle, establishing a different expectation with regard to cycling, finding others to cycle with, and using safe and comfortable cycling facilities. Survey questions about e-bikes, adult trikes, and tandems show the variety of bicycle types available, but point to the need for higher-capacity bikeways and education about sharing bikeways safely. The report ends with several issues for further consideration, including risks for older cyclists of color, ways that caregiving can enhance or reduce cycling benefits, and how injury recovery can affect a return to cycling, or not. The population of older adults is growing, and examining the needs of this group ensures a community’s ability to create environments conducive to equitable mobility for all

Cycling Past 50: A Closer Look into the World of Older Cyclists

This document reports on 2,300 responses to a nationwide survey of older adults who cycle. The survey, open from February through September 2020, includes questions about a rider’s cycling history, current cycling habits, and falls. It includes a visual preference survey of various cycling facilities and an online journaling option for two rides subsequent to completing the survey (results of the online journals will be available in the summer 2021). Responses reflect the impact of COVID-19 on older adults’ cycling habits, the impact of aging on ability and agility, the impact of the built environment, types of bicycles, and opportunities to cycle with others. Responses were analyzed by gender and age. Questions such as cycling frequency and falls were compared to a modified version of Geller’s four types of cyclists. Key take-aways include: Many older adults will need to adapt to their changing cycling abilities with a different bicycle, a different expectation about their cycling experience, and local programs to encourage sustained cycling. A fair number of respondents learned to cycle as an adult which suggests that local programs can also encourage older adults to learn to ride and how to select a bicycle. Lower cycling rates may result from not having a bikeable or proper-fitting bicycle, or the money to fix or purchase a bike. Questions posed for further consideration include: Can education and outreach help reduce near misses? Can planning and engineering help reduce near misses, especially in areas where more older adults cycle? How can falls due to poor infrastructure or maintenance or the actions of others be reduced

Intergroup Dialogue with High School Participants

Liberatory education facilitates identity expression, promotes empathy and understanding across difference, and builds capacity for recognizing and resisting oppressive social structures. However, many students’ educational experiences lack intentional practices that subvert societal intolerance. Without these practices, education can perpetuate social group divide without empowering students to create social change. The practice of dialogue, specifically critical intergroup dialogue, brings together participants from various social group identities in facilitated conversations in pursuit of social transformation. This project is an exploration of intergroup dialogue with high school students. For the research, I carried out a phenomenological study by co-facilitating a dialogue group with seven youth from six countries. The analysis of the study data, namely of the students’ insights, informed the curriculum presented in this field project. The curriculum is meant for practitioners to adapt to their community contexts. In order to build a more peaceful world and to respond to violence against marginalized communities, it is imperative to continue to develop critical peace education interventions that respond to racial, class, sociopolitical, gender, national and religious conflict. This study and corresponding curriculum respond to this need by making critical intergroup dialogue more accessible to high school students

Enhancing Older Adults’ Mobility in Active Living and Tiered Living Communities

The U.S. population is aging rapidly. As people get older, they increasingly face issues such as increased susceptibility to injuries and the need to be assisted with many day-to-day activities. Older adults have the opportunity to opt-in to live in an older adult community (OAC) based on their needs and capabilities. This study comprehensively reviews existing governing development regulations and design criteria related to the older adults’ communities, conducts surveys among people involved with some of these communities in California, and recommends improvements to community design for active living and tiered living communities. This study proposes a new scoring system to evaluate the overall life-space mobility of OACs and the surrounding areas. For each of the ten communities within California, the area\u27s Active Mobility Infrastructure (AMI), both inside and outside, and Permeability (PERM) are assessed. Furthermore, the study aims to comprehend how residents feel about the available facilities and how they are utilized through a survey that includes questions regarding how frequently residents partake in active transportation within and outside their communities and assesses residents’ financial and educational standings. Using Welch’s T-Test, Pearson’s Correlation Coefficient, and a Multinomial Logit Regression model, this study addresses three questions: (1) Are there any statistically significant differences in the transportation connection qualities within and surrounding the older adult communities perceived by their residents? (2) Are there strong correlations between the quality of transport connections and the walking frequency of the residents? (3) What are the main influential factors of walking frequency? The findings from this research can aid transportation professionals in improving the governing development regulations and associated design criteria for better person-environment fit in older living communities

Marine Platform of Probable Sangamon Age, and Associated Terrace Deposits, Cape Thompson Area, Northwestern Alaska

Reports geomorphic studies, as part of the US Atomic Energy Commission's investigations in this area 1958-1962. A coastal terrace, observed and measured along a 20-mi section crossing Ogotoruk Creek, is described and its origin, age, and morphology discussed. The feature is complex, consisting of a marine platform planed across bedrock, overlying marine and beach deposits, and a depositional upper surface of nonmarine sediments which coincides in area and configuration with the platform, possibly as a result of factors unique to polar areas. The marine platform and gravels record the last high stand of sea level, 28-40 ft above the present, which occurred about 38,000 yr ago. Other evidence in the area indicates still higher seas in earlier times

A Preliminary Archaeological Predictive Model for the US 30 Transportation Corridor, Portland, Oregon to Astoria, Oregon

This thesis is a preliminary archaeological predictive model and project-planning tool created for the Oregon Department of Transportation (ODOT) as part of a statewide planning effort to enhance the agency's ability to assess the potential impacts of highway projects on archaeological resources. This model addresses the archaeological sensitivity of the US 30 highway corridor from Portland, Oregon to Astoria, Oregon. The highway corridor is divided into 7 separate segments for management purposes and each segment is given a low, medium, or high probability rating for its potential to yield archaeological resources in this model. The ratings are accompanied by planning and maintenance recommendations to be integrated into a comprehensive planning document for the corridor. Probability determinations are based on State Historic Preservation Office (SHPO) archaeological records, physiographic data, dominant vegetation zones, General Land Office maps, ethnographic accounts, and historical records. The precise utility of this model is unknown because cross-tabulations that compare actual and model assigned presence or absence of resources have not been made. Low probability ratings are assigned to 27% of the corridor. Medium probability segments comprise 15% of the corridor. High probability rating account for 58% of the total length of the corridor. The segment with the highest site density is segment 2, averaging .63 archaeological sites per mile. The archaeological probability ratings were initially omitted from the Draft Corridor Management Plan of 1998, but have been included in the Final Corridor Management Plan of 1999. The predictive model results were incorrectly added to the document and consequently create false impressions. In the Final Corridor Management Plan the number of sites listed for segment 2 is incorrect. It is indicated that seven archaeological sites are present within the corridor, but the actual number is fourteen. Furthermore, the percentage ratings of low, medium, and high archaeological probability are erroneously provided for segments 3, 4, and 7 in the final plan. Ultimately this report has proven useful to ODOT archaeological staff, however signs indicate that the data provided to planning personnel has had little impact on project planning and design

Effectiveness of Ledipasvir/Sofosbuvir with/without Ribavarin in Liver Transplant Recipients with Hepatitis C.

Background and Aims: Recurrent infection of hepatitis C virus (HCV) in liver transplant (LT) recipients is universal and associated with significant morbidity and mortality. Methods: We retrospectively evaluated the safety and efficacy of ledipasvir/sofosbuvir with and without ribavirin in LT recipients with recurrent genotype 1 hepatitis C. Results: Eighty-five LT recipients were treated for recurrent HCV with ledipasvir/sofosbuvirwith and without ribavirin for 12 or 24 weeks. The mean (± standard deviation [SD]) time from LT to treatment initiation was 68 (±71) months. The mean (± SD) age of the cohort was 63 (±8.6) years old. Most recipients were male (70%). Baseline alanine transaminase, total bilirubin, and HCV ribonucleic acid (RNA) values (± SD) were 76.8 (±126) mg/dL, 0.8 (±1.3) U/L, and 8,010,421.9 (±12,420,985) IU/mL, respectively. Five of 43 recipients who were treated with ribavirin required drug cessation due to side effects, with 4 of those being anemia complications. No recipient discontinued the ledipasvir/sofosbuvir. Eighty-one percent of recipients had undetectable viral levels at 4 weeks after starting therapy, and all recipients had complete viral suppression at the end of therapy. The sustained viral response at 12 weeks after completion of therapy was 94%. Conclusion : Ledipasvir and sofosbuvir with and without ribavirin therapy is an effective and well-tolerated interferon-free treatment for recurrent HCV infection after LT. Anemia is not uncommon in LT recipients receiving ribavirin

Enhancing Older Adults\u2019 Mobility in Active Living and Tiered Living Communities

ZSB12017-SJAUXThe U.S. population is aging rapidly. As people get older, they increasingly face issues such as increased susceptibility to injuries and the need to be assisted with many day-to-day activities. Older adults have the opportunity to opt-in to live in an older adult community (OAC) based on their needs and capabilities. This study comprehensively reviews existing governing development regulations and design criteria related to the older adults\u2019 communities, conducts surveys among people involved with some of these communities in California, and recommends improvements to community design for active living and tiered living communities. This study proposes a new scoring system to evaluate the overall life-space mobility of OACs and the surrounding areas. For each of the ten communities within California, the area's Active Mobility Infrastructure (AMI), both inside and outside, and Permeability (PERM) are assessed. Furthermore, the study aims to comprehend how residents feel about the available facilities and how they are utilized through a survey that includes questions regarding how frequently residents partake in active transportation within and outside their communities and assesses residents\u2019 financial and educational standings. Using Welch\u2019s T-Test, Pearson\u2019s Correlation Coefficient, and a Multinomial Logit Regression model, this study addresses three questions: (1) Are there any statistically significant differences in the transportation connection qualities within and surrounding the older adult communities perceived by their residents? (2) Are there strong correlations between the quality of transport connections and the walking frequency of the residents? (3) What are the main influential factors of walking frequency? The findings from this research can aid transportation professionals in improving the governing development regulations and associated design criteria for better person-environment fit in older living communities

Geologic Investigations in Support of Project Chariot, Phase Iii, in the Vicinity of Cape Thompson, Northwestern Alaska--Preliminary Report

BS>Geologic investigations were made at the Chariot test site, at the mouth of Ogotoruk Creek in the vicinity of Cape Thompson, Alaska. IN the area within a 15-mile radius of the site, bedrock consists entirely of consolidated clastic and chemical sediments. The test excavation lies entirely in frozen mudstone which is complexly folded and faulted. Moisture determinations conducted within 10 ft of the surface indicated that the moisture content of the rock ranges from 3.1% in the thawed mudstone to 12.5% in the frozen mudstone. The use of refrigerated diesel fuel as drilling fluid in Holes Charlie and Dog in 1960 overcame the collapse of drill-hole walls owing to thawing of permafrost experienced in drilling by conventional techniques. Work on coastal processes was focused on establishing a physical background for ecological studies being conducted by other investigators and on characterizing the natural movement of sediment as an aid in evaluating the success and safety of the proposed nuclear test. Piston-core samples from lagoons which do not contain the mouths of rivers and streams showed that only about 10 cm of sediment were laid down in the lagoons since the last major rise of sea level. The shoreline history of the area was inferred from these samples. The two new holes were used to provide temperature information needed for a quantitative evaluation of the thermal regime ot lower Ogotoruk Creek Valley. The thermal regime of permafrost was found to not be in equilibrium with the present position of the shoreline or the present climate. Preliminary calculations indicated that the flow of heat to the surface from the earth's interior is on the order of one-millionth of a calorie per square centimeter of surface per second. A series of gravity measurements between Kotzebue and Point Hope indicated a broad uneven gravity low with double minimums near Cape Seppings and Kivalina. The possibility of radioactive contamination of shallow and deep aquifers existing in the area was investigated. (M.C.G.

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

Introduction: We hypothesized that common Alzheimer's disease (AD)-associated variants within the triggering receptor expressed on myeloid (TREM) gene cluster influence disease through gene expression. Methods: Expression microarrays on temporal cortex and cerebellum from ∼400 neuropathologically diagnosed subjects and two independent RNAseq replication cohorts were used for expression quantitative trait locus analysis. Results: A variant within a DNase hypersensitive site 5′ of TREM2, rs9357347-C, associates with reduced AD risk and increased TREML1 and TREM2 levels (uncorrected P = 6.3 × 10−3 and 4.6 × 10−2, respectively). Meta-analysis on expression quantitative trait locus results from three independent data sets (n = 1006) confirmed these associations (uncorrected P = 3.4 × 10−2 and 3.5 × 10−3, Bonferroni-corrected P = 6.7 × 10−2 and 7.1 × 10−3, respectively). Discussion: Our findings point to rs9357347 as a functional regulatory variant that contributes to a protective effect observed at the TREM locus in the International Genomics of Alzheimer's Project genome-wide association study meta-analysis and suggest concomitant increase in TREML1 and TREM2 brain levels as a potential mechanism for protection from AD