A Case of Vogt-Koyanagi-Harada Disease Associated With Polycystic Ovary Syndrome

We report a female patient diagnosed as Vogt-Koyanagi-Harada (VKH) and polycystic ovary syndrome (PCOS). She has diagnosed as VKH with diminished vision, bilateral serous retinal detachment, the signs of fundus fluorescein angiography and the findings of optical coherence tomography. The patient was referred to the gynecology clinic for her complaints as weight gain, hirsutismus and amenorrhea. She has also been diagnosed with PCOS. With oral steroid treatment, visual acuity has improved and the detachments have resolved within a month. VKH disease may be associated with polycystic ovary syndrome. The two conditions may have a common autoimmune pathogenesis

Üniversite Öğrencilerinin Karar Verme Stilleri ile Üniversite Yaşamına Uyum Düzeyleri Arasındaki İlişkinin İncelenmesi

Bu araştırmada, üniversite öğrencilerinin karar verme stilleri ile üniversite yaşamına uyum düzeyleri arasındaki ilişkinin incelenmesi amaçlanmıştır. Araştırmada, nicel araştırma yöntemlerinden ilişkisel tarama modeli kullanılmıştır. Araştırmanın katılımcılarını, 2021-2022 eğitim öğretim yılında Türkiye’nin farklı üniversitelerinde eğitimlerine devam eden 257 kadın ve 114 erkek olmak üzere toplam 371 öğrenci oluşturmaktadır. Çalışmanın verileri, “Melbourne Karar Verme Stilleri Ölçeği”, “Üniversite Yaşamına Uyum Ölçeği” ve “Kişisel Bilgi Formu” aracılığıyla toplanmıştır. Verilerin analizinde, Pearson korelasyon analizi, ilişkisiz örneklemler t testi, tek yönlü varyans analizi (ANOVA) ve çoklu doğrusal regresyon analizi kullanılmıştır. Araştırmadan elde edilen bulgulara göre, öğrencilerin karar verme stilleri ile üniversite yaşamına uyum düzeyleri arasında anlamlı ilişki olduğu tespit edilmiştir. Yapılan regresyon analizine göre, karar verme özsaygısının kişisel uyumu anlamlı düzeyde yordadığı, dikkatli karar verme stilinin ise akademik ve sosyal uyumu anlamlı olarak yordadığı görülmüştür. Ayrıca demografik değişkenlere göre yapılan karşılaştırmada; kadınların panik karar verme stili puanlarının erkeklerin puanlarından anlamlı olarak daha yüksek olduğu, sınıf değişkeninin ise öğrencilerin karar verme stilleri ve üniversite yaşamına uyum düzeyleri açısından anlamlı bir farklılık yaratmadığı saptanmıştır. Çalışmadan elde edilen bütün bulgular bir arada değerlendirildiğinde, öğrencilerinin üniversite yaşamına uyum sağlamalarında karar verme stillerinin önemli rol oynadığı belirtilebilir

Williams-Beuren Syndrome: A Case Report

Williams syndrome is a rare neurodevelopmental disorder caused by the spontaneous deletion of genetic material from the region q11.23 of one member of the pair of chromosome 7, so that the person is hemizygous for those genes. Syndrome is a rarely genetic multisystem disorder that occurs equally in all ethnic groups and both sexes. Williams syndrome is a developmental disorder that affects many parts of the body. This condition is characterized by mild to moderate intellectual disability or learning problems, unique personality characteristics, distinctive facial features, and heart and blood vessel (cardiovascular) problems. The diagnosis of this syndrome is based on recognition of the characteristic pattern of dysmorphic facial and physical features. The diagnosis is typically suspected based on symptoms and confirmed by genetic testing. Treatment includes special education programs and various types of therapy. Surgery may be done to correct heart problems. Dietary changes or medications may be required for high blood calcium. Life expectancy is less than that of the general population, mostly due to the increased rates of heart disease. This case report presents the story of 10-year-old girl who suffers from Williams syndrome. Cardiac murmur, mental retardation, severe malocclusion problems, wide mouth, diestama, full lip, periorbital fulness, epicanthal fold, stellate iris pattern, short stature, weaknesses in retional/conceptual language and short term memory observed in this patient. In this study, patient’s salivary glands and deciduous anterior tooth were investigated by detailed diagnostic methods (USG, micro-CT). The overall purpose of this case was to diagnose dental manifestations and evaluate physical and clinical characteristics of present case with Williams Syndrome

Alerjik kontakt dermatitli olgularda yama testi: Üç yillik retrospektif Tekirda? ili sonuçlari]

Background and Design: Allergic contact dermatitis (ACD) is a delayed-type hypersensitivity reaction to allergens in individuals who have been previously sensitized to an allergen. The causative allergens may change in time and may vary by geographic area and population. Materials and Methods: We retrospectively analyzed the patch test results and characteristics of 169 patients-107 (63.3%) male, 62 (36.7%) female-, who received the diagnosis of ACD between 2011 and 2014. Results: The mean age of the patients was 41.06 years and the mean disease duration was 19.5 months. The most common occupation was service sector/housewifery (26.6%). The most frequent localization of the disease was the hands (n=105, 73%) and 50.3% of patients were skin test positive to at least one allergen. The most frequent seven allergens were nickel sulfate (n=50, 29.6%), cobalt chloride (n=23, 13.6%), potassium dichromate (n=22, 13%), sesquiterpene lactone mix (n=18, 10.7%), thiuram (n=10, 5.9%), clioquinol mix (n=10, 5.9%), and 4-tert-butilfenol formaldehyde resin (n=10, 5.9%), respectively. On the other hand, no patient, had a positive reaction to N-Isopropyl-N-phenyl-4-phenylenediamine, epoxy resin, balsam of peru, formaldehyde, quaternium-15, primin, tixocortol-21-pivalate, and fragrance mix-2. Conclusion: In comparison of this study which is the first report of patch test results of patients in Tekirdag-a city in Thrace region-and other studies that report patch test results in different regions of our country; it was observed that the mean age of patients in the present study was higher than in other studies and there was no significant difference in terms of occupations of the patients and localization of the disease between the eastern region and Thrace region. We believe that further multicenter studies in a larger population performed in different cities of the country are needed to specify allergen characteristics of Thrace region

Examining Hakkari University Students’ Views on the Nature of Science and Epistemological Thoughts

DergiPark: 371216trakyasobedTheaim of the study is to examine the relationship between the nature of scienceand epistemological views of undergraduate and associate degree studentsstudying at Hakkari University. Quantitative design was preferred in the study.The Scientific Epistemological Beliefs Scale, adapted by Turkish, by Acat,Tüken and Karadağ developed by Elder has been applied to determineepistemological views. The Scientific Nature Scale developed by Özgenen (2013) wasused. The population of the research is the undergraduate and pre-graduatestudents who from the universities that continue to the developing areestablished in 2007-2008. Due to the selected by appropriate sampling method, thesample of the study is 230 undergraduate and undergraduate students attend the HakkâriUniversity. According to thegeneral results of the research, it was found that the mean scores of thenatural opinions of the teachers’ candidates were averaged points and the epistemologicalviews were also prone to scepticism. In addition, a statistically significantrelationship was found between the participants’ natural views of science andtheir epistemological views.Araştırmanın amacı HakkariÜniversitesinde eğitim gören lisans ve ön lisans öğrencilerinin bilimin doğasıve epistemolojik görüşleri arasındaki korelasyon çalışması olarakbelirlenmiştir. Araştırmada nicel desen tercih edilmiştir. Epistemolojik görüşlerin belirlenmesi içinElder tarafından geliştirilen Acat, Tüken ve Karadağ tarafından Türkçeyeuyarlanan Bilimsel Epistemolojik İnanç Ölçeği, bilimin doğası görüşlerininincelenmesi için de Özgelen (2013) tarafından geliştirilen Bilimin DoğasıÖlçeği kullanılmıştır. Araştırmanın evreni 2007-2008 yıllarında kurulan vegelişmekte olan üniversitelere devam eden lisans ve ön-lisans öğrencileridir. Araştırmada uygun örnekleme yöntemi uygulanarak Hakkâri Üniversitesindeeğitim gören 230 lisans ve ön lisans öğrencisine yer verilmiştir. Araştırmanıngenel sonuçlarına göre öğretmen adaylarının bilimin doğası görüşlerinin ortalamapuana yakın değerler aldığı, epistemolojik görüşlerinin de skeptik düşünceyeyatkın olduğu bulunmuştur. Bunun yanı sıra katılımcıların bilimin doğasıgörüşleri ile epistemolojik görüşleri arasında istatistiksel olarak anlamlı birilişki tespit edilmiştir.

Parallelized preconditioned model building algorithm for matrix factorization

Matrix factorization is a common task underlying several machine learning applications such as recommender systems, topic modeling, or compressed sensing. Given a large and possibly sparse matrix A, we seek two smaller matrices W and H such that their product is as close to A as possible. The objective is minimizing the sum of square errors in the approximation. Typically such problems involve hundreds of thousands of unknowns, so an optimizer must be exceptionally efficient. In this study, a new algorithm, Preconditioned Model Building is adapted to factorize matrices composed of movie ratings in the MovieLens data sets with 1, 10, and 20 million entries. We present experiments that compare the sequential MATLAB implementation of the PMB algorithm with other algorithms in the minFunc package. We also employ a lock-free sparse matrix factorization algorithm and provide a scalable shared-memory parallel implementation. We show that (a) the optimization performance of the PMB algorithm is comparable to the best algorithms in common use, and (b) the computational performance can be significantly increased with parallelizatio

Association of platelet count and platelet indices with cranial meningioma

Introduction and Objectives: In this study, we aimed to investigate whether platelet count (PLT) and platelet indices included mean platelet volume (MPV), platecrit (PCT), platelet distribution width  (PDW) values can be used as diagnostic markers in cranial meningiomas. Materials and Methods: The study included results of 29 patient and 47 healthy contributors. Based on pathologies, the patients were divided into two groups. The first group included meningioma patients and the second one included healthy individuals. Healthy contributors named control group. Platelet count and platelet indices were determined using Sysmex XN 550 haematology analyzer. The preoperative platelet count (PLT) and platelet indices included mean platelet volume (MPV), platecrit (PCT), platelet distribution width  (PDW) values were recorded from the routine laboratory tests. Results: There was no statistically significant difference in PLT between the meningioma and healthy groups (p = 0.217). There was a statistically significant difference in PCT between the meningioma group and the healthy group (p = 0.002). There was a statistically significant difference in PDW between meningioma group and healthy group (p = 0.001). In terms of MPV, there was a statistically significant difference between meningioma group and the healthy group (p = 0.001) Conclusion: Platelet count and indices are easily available in the routine blood tests. Despite the retrospective design and small sample size, our findings suggest that altered MPV, PDW and PCT levels might serve as potential biomarkers for the diagnosis of meningiomas