Influence of periodontitis to subgingival microflora development around osseointegrated implants

Abstract no. 1373published_or_final_versio

Salivary immunoglobulin A levels in "rapid" and "slow" plaque formers

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Antibiotic sensitivity of putative pathogens in Chinese periodontal patients

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Healing responses following surgical/non-surgical treatment in residual periodontally-involved sites

Objective: The aim of this study was to evaluate the healing responses following surgical or repeated non-surgical treatment in residual pockets of previously non-surgically treated periodontitis patients. Methods: 12 female and 4 male subjects (mean age = 44.5 years) were recruited for this split-mouth, single-blinded study. Matched-paired-sites with residual probing pocket depth ≥6mm and bleeding on probing were selected in each patient. Presence of supragingival plaque (Pl%), bleeding on probing (BOP%), probing pocket depth (PPD) and probing attachment level (PAL) were recorded at baseline and 3 months after treatment. Test sites were selected randomly for repeated non-surgical debridement under local anaesthesia while control sites received surgical treatment. Results: Full-mouth Pl% decreased from 20% at baseline to 17% at 3 months and the BOP% decreased from 25% to 22%. Mean PPD reduction for test and control sites were 3.3mm and 3.1mm (p>0.05, paired t-test), mean PAL gains were 2.5mm and 1.7mm (p>0.05), and mean increases in recession were 0.8mm and 1.4mm (p<0.05). Conclusion: The healing responses in residual periodontally-involved sites following non-surgical or surgical treatment were similar and both treatment modalities were effective in PPD reduction and gain of PAL, but surgical debridement caused more recession.postprin

Peri-implant bone level changes in patients with stable periodontal conditions

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Clinical and microbiological effects of metronidazole dental gel in treated adult periodontitis subjects

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Adjunctive effect of hormone replacement therapy on periodontal treatment responses

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Clinical and microbiological response to mechanical periodontal treatment in Chinese adult periodontitis patients

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Estimation of the gray level variations in soft and hard peri-implant tissue from X-ray images

In the treatment and assessment of periodontal disease periapical films are taken at regular intervals. The films are compared around the region of the implant to monitor the changes that have taken place. A computer-assisted method to automate this process is presented here. To compare two images, a pair of X-ray images are superimposed on top of each other. The images are normalized and transformed to obtain the best fit. These images are subtracted and the difference in pixel values are used as a basis for analysis. A method for improving the alignment accuracy and contrast compensation is highlighted.published_or_final_versio

Single nucleotide polymorphisms of complement component 5 and periodontitis

BACKGROUND AND OBJECTIVE: Polymorphisms of host defence genes might increase one's risks for periodontitis. This study investigated whether tagging single nucleotide polymorphisms (SNPs) of the gene encoding complement component 5 (C5) are associated with periodontitis in a Hong Kong Chinese population. MATERIAL AND METHODS: Eleven tagging SNPs of 229 patients with at least moderate periodontitis and 207 control subjects without periodontitis were genotyped using an i-plexGOLD MassARRAY mass-spectrometry system. RESULTS: Genotype AG of SNP rs17611 was more prevalent in the group of periodontitis patients than in the controls (54.6% vs. 41.7%, p = 0.007). The haplotype CGCA of the haplotype block consisting of rs1035029, rs17611, rs25681 and rs992670 was significantly associated with periodontitis in a dominant model (p = 0.001). The SNP rs17611 showed high linkage disequilibrium with rs1035029, rs25681 and rs992670. Smoking was also significantly associated with periodontitis (p = 0.006). CONCLUSION: The tagging SNP rs17611 of the C5 gene and smoking may be associated with periodontitis among the Hong Kong Chinese population.postprin