Performance of entrepreneurial Chinese immigrants in network marketing organisations

Immigrant entrepreneurship has started attracting much empirical research in the literature. There is an increasing trend in Australia where a large number of Chinese immigrants have joined network marketing organisations (NMOs). However, only a small number of empirical studies on NMOs have been conducted and most of these do not examine the factors contributing to explaining the performance of Chinese immigrants in NMOs. The objective of this paper is to develop an integrative model to examine the factors contributing to the action of Chinese immigrants who engage in network marketing business

Network Marketing Businesses and Chinese Ethnicity Immigrants in Australia

© 2016 International Council for Small Business This study adopts two theoretical perspectives, Social Cognitive Theory and Theory of Planned Behavior, to examine a model of network marketing business participation by Chinese immigrants in Australia. A structural equations modeling analysis showed that the social environment within a network marketing organization positively influences the self-efficacy of Chinese network marketers and their desire to seek opportunities. These factors positively influence the actions undertaken by network marketers, and subsequently, impact positively on their performance outcome

Identifying and measuring motivational factors in conducting network marketing business by Chinese immigrants

Drawing upon symbolic self-completion theory and immigrant entrepreneurship literature, we develop a four factor scale to measure the motivations of Chinese network marketers in conducting network marketing business. An exploratory factor analysis was conducted to determine the underlying factorial structure of the scale to measure network marketersâ motivation of conducting network marketing business. The data were collected from 227 Chinese immigrant network marketers in Australia. The results suggest that the scale contains four factors: extrinsic motivation, intrinsic motivation, the motivation of establishing oneâs own business with low cost (risk) and motivation of self-satisfaction. This finding suggests that successful network marketers are motivated intrinsically, which is contradictory to Kuntzeâs (2001) result which suggests that network marketers are motivated extrinsicall

Predictors of the groupwork experience: generic skill development, peer appraisals, and country of residence

Humphrey et al. (1997) argued that a range of generic skills are important in enhancing the experience of groupwork for students. These skills include problem solving skills, leadership skills, research skills, study skills, and communication skills. However, little is known about the extent to which the development of such skills impact on the students' experience of groupwork, Students are also rarely given opportunities to develop their performance management skills in group assignments, despite often being expected to evaluate the performance of their peers. Those doing the appraisal may not learn how to provide feedback and justify their evaluations. It also means that those being appraised do not receive feedback regarding their strengths and whereimprovements are needed. As a consequence, students tend to report negative experiences of groupwork when they have to assess and be assessed by their peers. The current study aims to examine the effects of generic skill development and peerevaluation on the students' evaluation of their group experience, following their participation on a group assignment

Career Experience of Asian Ethnicity Immigrants In Australia

The literature has shown that most immigrants reported a negative experience with their career in their newly adopted countries. In particular, they complained of loss in income and status, especially for those from non-English speaking countries. The Social Psychology literature has been shown that ethnic identity can influence an immigrant's perception of the fairness of organizational recruitment and job acceptance intention. However, little is known of the impact of immigrant's ethnic identity and how this impacts on their career experience. This is the subject of the current paper as we draw upon the literature on ethnic identity and social cognition career theory to examine the career experience 196 `visible racial minority' individuals in Australia. These individuals were immigrants from Asia (first generation Asian Australians) and Asian-born Australians (second generation Asian Australians) in Australia

Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer.

BACKGROUND:Although canonical Wnt signaling is known to promote tumorigenesis in pancreatic ductal adenocarcinoma (PDAC), a cancer driven principally by mutant K-Ras, the detailed molecular mechanisms by which the Wnt effector β-catenin regulates such tumorigenesis are largely unknown. We have previously demonstrated that β-catenin's differential usage of the Kat3 transcriptional coactivator cyclic AMP-response element binding protein-binding protein (CBP) over its highly homologous coactivator p300 increases self-renewal and suppresses differentiation in other types of cancer. AIM/METHODS:To investigate Wnt-mediated carcinogenesis in PDAC, we have used the specific small molecule CBP/β-catenin antagonist, ICG-001, which our lab identified and has extensively characterized, to examine its effects in human pancreatic cancer cells and in both an orthotopic mouse model and a human patient-derived xenograft (PDX) model of PDAC. RESULTS/CONCLUSION:We report for the first time that K-Ras activation increases the CBP/β-catenin interaction in pancreatic cancer; and that ICG-001 specific antagonism of the CBP/β-catenin interaction sensitizes pancreatic cancer cells and tumors to gemcitabine treatment. These effects were associated with increases in the expression of let-7a microRNA; suppression of K-Ras and survivin; and the elimination of drug-resistant cancer stem/tumor-initiating cells

Smartphone-based remote monitoring of vision in macular disease enables early detection of worsening pathology and need for intravitreal therapy

BACKGROUND/AIMS: To assess the outcomes of home monitoring of distortion caused by macular diseases using a smartphone-based application (app), and to examine them with hospital-based assessments of visual acuity (VA), optical coherence tomography-derived central macular thickness (CMT) and the requirement of intravitreal injection therapy. DESIGN: Observational study with retrospective analysis of data. METHODS: Participants were trained in the correct use of the app (Alleye, Oculocare, Zurich, Switzerland) in person or by using video and telephone consultations. Automated threshold-based alerts were communicated based on a traffic light system. A ‘threshold alarm’ was defined as three consecutive ‘red’ scores, and turned into a ‘persistent alarm’ if present for greater than a 7-day period. Changes of VA and CMT, and the requirement for intravitreal therapy after an alarm were examined. RESULTS: 245 patients performing a total of 11 592 tests (mean 46.9 tests per user) were included and 85 eyes (164 alarms) examined. Mean drop in VA from baseline was −4.23 letters (95% CI: −6.24 to −2.22; p<0.001) and mean increase in CMT was 29.5 µm (95% CI: −0.08 to 59.13; p=0.051). Sixty-six eyes (78.5%) producing alarms either had a drop in VA, increase in CMT or both and 60.0% received an injection. Eyes with persistent alarms had a greater loss of VA, −4.79 letters (95% CI: −6.73 to −2.85; p<0.001) or greater increase in CMT, +87.8 µm (95% CI: 5.2 to 170.4; p=0.038). CONCLUSION: Smartphone-based self-tests for macular disease may serve as reliable indicators for the worsening of pathology and the need for treatment

Early Cardiac Effects of Contemporary Radiation Therapy in Patients With Breast Cancer

Purpose To characterize the early changes in echocardiographically derived measures of cardiac function with contemporary radiation therapy (RT) in breast cancer and to determine the associations with radiation dose-volume metrics, including mean heart dose (MHD). Methods and Materials In a prospective longitudinal cohort study of 86 patients with breast cancer treated with photon or proton thoracic RT, clinical and echocardiographic data were assessed at 3 time points: within 4 weeks before RT initiation (T0), within 3 days before 6 weeks after the end of RT (T1), and 5 to 9 months after RT completion (T2). Associations between MHD and echocardiographically derived measures of cardiac function were assessed using generalized estimating equations to define the acute (T0 to T1) and subacute (T0 to T2) changes in cardiac function. Results The median estimates of MHD were 139 cGy (interquartile range, 99-249 cGy). In evaluating the acute changes in left ventricular ejection fraction (LVEF) from T0 to T1, and accounting for the time from RT, age, race, preexisting cardiovascular disease, and an interaction term with anthracycline or trastuzumab exposure and MHD, there was a modest decrease in LVEF of borderline significance (0.22%; 95% confidence interval [CI], –0.44% to 0.01%; P = .06) per 30-day interval for every 100 cGy increase of MHD. Similarly, there was a modest worsening in longitudinal strain (0.19%; 95% CI, –0.01% to 0.39%; P = .06) per 30-day interval for each 100 cGy increase in MHD. We did not find significant associations between MHD and changes in circumferential strain or diastolic function. Conclusions With modern radiation planning techniques, there are modest subclinical changes in measures of cardiac function in the short-term. Longer-term follow-up studies are needed to determine whether these early changes are associated with the development of overt cardiac disease

Synthesis and Enhanced Field-Emission of Thin-Walled, Open-Ended, and Well-Aligned N-Doped Carbon Nanotubes

Thin-walled, open-ended, and well-aligned N-doped carbon nanotubes (CNTs) on the quartz slides were synthesized by using acetonitrile as carbon sources. As-obtained products possess large thin-walled index (TWI, defined as the ratio of inner diameter and wall thickness of a CNT). The effect of temperature on the growth of CNTs using acetonitrile as the carbon source was also investigated. It is found that the diameter, the TWI of CNTs increase and the Fe encapsulation in CNTs decreases as the growth temperature rises in the range of 780–860°C. When the growth temperature is kept at 860°C, CNTs with TWI = 6.2 can be obtained. It was found that the filed-emission properties became better as CNT growth temperatures increased from 780 to 860°C. The lowest turn-on and threshold field was 0.27 and 0.49 V/μm, respectively. And the best field-enhancement factors reached 1.09 × 105, which is significantly improved about an order of magnitude compared with previous reports. In this study, about 30 × 50 mm2 free-standing film of thin-walled open-ended well-aligned N-doped carbon nanotubes was also prepared. The free-standing film can be transferred easily to other substrates, which would promote their applications in different fields