Safety and efficacy of PNL vs RIRS in the management of stones located in horseshoe kidneys: A critical comparative evaluation

Aim: To assess the efficacy and safety of two different techniques (Percutaneous nephrolithotomy (PNL) vs Retrograde intrarenal surgery (RIRS)) in the management of stones in patients with horseshoe kidneys (HSK). Patients and methods: Departmental files of 88 cases with radiopaque kidney stones in horseshoe kidneys undergoing two different approaches (PNL vs RIRS) were evaluated with respect to the success and complication rates of in a retrospective manner. In addition to the factors related with the procedures (success and complication rates, additional procedures), patient and stone characteristics were all well evaluated. Findings obtained in both groups were evaluated in a comparative manner with respect to the statistical significance. Results: Stone free rates were comparable in both groups after 1-week period (81.6% PNL vs 80% RIRS). As well as 3 months evaluation (84.2% PNL and 82.0% RIRS). The percentage of the cases with residual fragments (> 4 mm) were similar in both groups and while all PNL procedures were completed in one session, mean number of RIRS sessions was higher (1.22 ± 0.05). Mean duration of the procedure was slightly higher in RIRS group and based on Clavien scoring system, despite a higher risk of Hb drop noted in patients treated with PNL, all complication rates were found to be similar in both groups. Conclusion: Our results demonstrate that of the available minimally invasive treatment alternatives, both PNL and RIRS could be safe and effective alternatives for renal stone removal in patients with HSK

The renal neoplastic lesions in non-functioning kidney patients who underwent simple nephrectomy

The simple nephrectomy is usually performed in daily urology practice for the non-functioning kidney. The aim of this study is to determine the incidental malignancy rate of the patients who underwent nephrectomy procedure. In total, 258 patients were included in the study. The patients who underwent simple nephrectomy and diagnosed as renal tumor between January 2003 and March 2016 for the non-functioning kidney at our department were recorded. There were 258 patients in this study. Of these patients;123 were male and 134 were female patients. The mean age of the patients was 52.33+17.63 years. The presence of stone formation was detected in 92 patients (35.65%). The renal malignancy was reported in 9 patients.Among the patients with malignancy; 2 patients were female and 7 patients were male. The mean age of the patients was 54.77+8.81 years. The pathological examination revealed that 6 patients were transitional cell carcinoma (TCC) of the renal pelvis, 2 patients were renal cell carcinoma, one patient was cystic nephroma. Interestingly, nephrolithiasis was detected only in one patient. The prevalence of all malignancy and the malignant tumor was 3.48% and 3.10% in this study. The final pathology showed that there is a risk of malignancy fort he patients with the non-functioning kidney. The clinicians should be aware that the patient may be diagnosed as renal tumor after pathological examination. [Med-Science 2018; 7(2.000): 247-8

Hydrophobic components from lycopodium complanatum L sub species chamaecyparissus(A. BR.)Doll

No Abstracts.Nigerian Journal of Natural Products and Medicine Vol.10(0) 2006: pp.82-8

Tp-e interval and Tp-e/QTc ratio are significantly Increased in patients with brain death

Objective: We aimed to investigate whether there is a change in Tp-e interval, Tp-e/ QT and Tp-e/QTc ratios in patients with brain death. Materials and Methods: Fifty brain death patients and 50 age and sex matched healthy controls were included in the study. In addition to routine evaluation, Tp-e interval, Tp-e / QT and Tp-e / QTc ratios were measured in 12-lead electrocardiography. Tp-e was measured in the precordial leads using the Tail method; the time from the peak of the T wave to the point where the wave reached the isoelectric line. Results: White blood cell, aspartate aminotransferase, alanine aminotransferase and high sensitive c reactive protein levels were significantly higher in patients with brain death. The frequency of patients with QTc prolongation, Tp-e interval, Tp-e/QT and Tp-e/QTc values were significantly higher in patients with brain death (p <0.05). Tp-e interval, Tp-e/QT and Tp-e/QTc values were found to be positively correlated with HsCRP (p<0.001 for all). Conclusion: Tp-e interval, Tp-e / QT and Tp-e / QTc ratios are increased in patients with brain death compared to healthy controls. The mechanisms of this association and possible relationship with neuroendocrine changes should be investigated in future studies

Dermatosurgical training model

Amaç: Çalışmamızla cerrahi işlemlerin uygulanacağı ve uygulayana deneyim kazandıracak bir model geliştirmeyi amaçladık.Materyal ve Metod: Deneysel işlem sonrası sakrifiye edilen ratların derileri çıkartıldı. Önceden hazırlanan çalışma tahtasına deri sabitlenerek üzerinde punch ve eksizyonel biyopsi, değişik dikiş yöntemleri, shave eksizyon ve flep uygulamaları çalışıldı.Bulgular: Modelimiz birçok cerrahi işlemde deneyim kazanmak için uygun bulundu.Tartışma: Ucuz ve oluşturması kolay olan bu modelin deneyim kazanmak isteyen kişiler için yararlı olacağını düşünmekteyiz.Aim: Our aim was to develope a training model on which dermatologic surgery procedures could be practiced.Material and Method: Skin were excised from sacrificed experimental rats. Rat skin was fixed on formerly prepared wood. Punch and excision biopsy, different suture techniques, shave excision and flap operations were practiced.Results: Our model was found to be useful for gaining practice for many surgical operations.Discussion: We consider that this cheap and easy to perform animal model could be useful for trainers of dermatosurgery