352 research outputs found

    Validity and responsiveness of the French version of the Ă–rebro musculoskeletal pain screening questionnaire in chronic low back pain

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    The assessment of a broad range of biopsychosocial aspects is important in the rehabilitation of patients with chronic low back pain (CLBP) for the prediction of outcome as well as for evaluation. The objective of this study was to test the responsiveness, construct validity and predictive value of the A-rebro Musculoskeletal Pain Screening Questionnaire (OMPSQ) compared to other instruments widely used to assess biopsychosocial aspects in patients with CLBP. 111 patients with CLBP admitted to an inpatient rehabilitation completed a set of questionnaires on biopsychosocial aspects at baseline and at discharge. Ninety-eight patients responded at three months for an assessment of the return to work status. Responsiveness of the OMPSQ, the ability to detect change in the construct of interest, was investigated by a set of hypotheses on correlations with widely used questionnaires. We tested the hypothesis that the changes in the OMPSQ would vary along with the responses in the Patient's Global Impression of Change. Prediction of disability at discharge, work status at three months and time to return to work was evaluated with linear, logistic and cox regression models. The OMPSQ showed good predictive values for disability and return to work and construct validity of the instrument was corroborated. Seventy-nine percent of our hypotheses for responsiveness could be confirmed, with the OMPSQ showing the second highest change during the rehabilitation. The OMPSQ can also be applied in patients with CLBP, but for the assessment of change in psychosocial variables one should add specific questionnaires

    Past warming trend constrains future warming in CMIP6 models

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    Future global warming estimates have been similar across past assessments, but several climate models of the latest Sixth Coupled Model Intercomparison Project (CMIP6) simulate much stronger warming, apparently inconsistent with past assessments. Here, we show that projected future warming is correlated with the simulated warming trend during recent decades across CMIP5 and CMIP6 models, enabling us to constrain future warming based on consistency with the observed warming. These findings carry important policy-relevant implications: The observationally constrained CMIP6 median warming in high emissions and ambitious mitigation scenarios is over 16 and 14% lower by 2050 compared to the raw CMIP6 median, respectively, and over 14 and 8% lower by 2090, relative to 1995–2014. Observationally constrained CMIP6 warming is consistent with previous assessments based on CMIP5 models, and in an ambitious mitigation scenario, the likely range is consistent with reaching the Paris Agreement target
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