Modeling of diffusion of injected electron spins in spin-orbit coupled microchannels

We report on a theoretical study of spin dynamics of an ensemble of spin-polarized electrons injected in a diffusive microchannel with linear Rashba and Dresselhaus spin-orbit coupling. We explore the dependence of the spin-precession and spin-diffusion lengths on the strengths of spin-orbit interaction and external magnetic fields, microchannel width, and orientation. Our results are based on numerical Monte Carlo simulations and on approximate analytical formulas, both treating the spin dynamics quantum-mechanically. We conclude that spin-diffusion lengths comparable or larger than the precession-length occur i) in the vicinity of the persistent spin helix regime for arbitrary channel width, and ii) in channels of similar or smaller width than the precession length, independent of the ratio of Rashba and Dresselhaus fields. For similar strengths of the Rashba and Dresselhaus fields, the steady-state spin-density oscillates or remains constant along the channel for channels parallel to the in-plane diagonal crystal directions. An oscillatory spin-polarization pattern tilted by 45$^{\circ}$ with respect to the channel axis is predicted for channels along the main cubic crystal directions. For typical experimental system parameters, magnetic fields of the order of Tesla are required to affect the spin-diffusion and spin-precession lengths.Comment: Replaced with final version (some explanations and figures improved). 8 pages, 6 figure

Guidelines for the use of cell lines in biomedical research

Cell-line misidentification and contamination with microorganisms, such as mycoplasma, together with instability, both genetic and phenotypic, are among the problems that continue to affect cell culture. Many of these problems are avoidable with the necessary foresight, and these Guidelines have been prepared to provide those new to the field and others engaged in teaching and instruction with the information necessary to increase their awareness of the problems and to enable them to deal with them effectively. The Guidelines cover areas such as development, acquisition, authentication, cryopreservation, transfer of cell lines between laboratories, microbial contamination, characterisation, instability and misidentification. Advice is also given on complying with current legal and ethical requirements when deriving cell lines from human and animal tissues, the selection and maintenance of equipment and how to deal with problems that may arise

The Energy Value and Energy Yields of Alfalfa Forage Depending on the Cutting Time in Forage-Seed Production System

Economic importance of alfalfa (Medicago sativa L.) is reflected in the production of high-quality forage, however, the seeds of alfalfa are valuable commodity in the domestic and international markets. In Serbia, the seed is produced in forage-seed mode of exploitation where the second or third growth is used for seed production, and the remaining growths are used for fodder. The aim of this work was to determine the influence of cuttings and time of cutting on total energy value of hay in a model of forage and seed production. The second and third cuts were used as seed cut. In the variant where the second cut was used as seed cut, the first cut was harvested at different times (A1-early, A2-medium early, A3-late and A4- very late). In the model where the third cut was used for seed, two pre-cuts were used for forage production (A5). In all the following variants, seed cut was followed by one more cutting (final cut), used for the production of fodder. The highest average total production (from pre-cut and final cut) of NEL (34606 MJha-1) and NEM (33811 MJha-1) was realized in the system of cutting with two pre-cuts. In the variant with single pre-cut, the highest yield was formed in the early system. Later cutting of the first cut causes decline of NEL production and it was the lowest in the system of very late cutting or 15.1 % less than in the early system and 38% lower than in the system of cutting with two pre-cuts. Delaying of utilization of alfalfa to the later stages of exploitation has contributed to the lower yield of NEM and in the medium early system and late system and especially in the very late cutting system, where by 22.2 % less was realized than in the early production system. Studies have shown that late cutting of first cut resulted in the reduction of nutritional value expressed in the amount of net energy per unit area

A natural-norm Successive Constraint Method for inf-sup lower bounds

We present a new approach for the construction of lower bounds for the inf-sup stability constants required in a posteriori error analysis of reduced basis approximations to affinely parametrized partial differential equations. We combine the “linearized” inf-sup statement of the natural-norm approach with the approximation procedure of the Successive Constraint Method (SCM): the former (natural-norm) provides an economical parameter expansion and local concavity in parameter—a small(er) optimization problem which enjoys intrinsic lower bound properties; the latter (SCM) provides a systematic optimization framework—a Linear Program (LP) relaxation which readily incorporates continuity and stability constraints. The natural-norm SCM requires a parameter domain decomposition: we propose a greedy algorithm for selection of the SCM control points as well as adaptive construction of the optimal subdomains. The efficacy of the natural-norm SCM is illustrated through numerical results for two types of non-coercive problems: the Helmholtz equation (for acoustics, elasticity, and electromagnetics), and the convection–diffusion equation.United States. Air Force Office of Scientific Research (Grant No. FA 9550-07-1-0425

Fake news and critical thinking in information evaluation

In the post-truth era we are constantly bombarded with “news” which is fabricated, distorted, and massaged information, published with the intention to deceive and mislead others. Such “news” has come to be known as “fake news”. The influence of fake news can have profound socio-political and cultural effects when translated into action. The ability to distinguish between real facts, fabricated stories, rumours, propaganda, or opinions is of paramount importance. The rapid proliferation of information through social media is now the norm. In this paper we consider the challenge of preparing students, in developing skills for recognising mis-information, dis-information and mal-information. We argue that critical thinking for evaluating information should now be considered a basic literacy, equally important to literacy itself, as well as information and information technology literacies. In this paper we revisit Bloom’s taxonomy of cognitive skills and represent what a learner can achieve at each level. We customise the traditional moral and ethical concepts suggested by the US Content Subcommittee of the ImpactCS Steering Committee to flag the ethical concerns over mis-information, dis-information and mal-information. We report on current levels of awareness and practices at the authors’ five higher education institutions, and reveal varying levels of awareness of the significance of critical literacy and different practices in each location. The paper concludes with an outline of future work

Reversing resistance to tembotrione in an Amaranthus tuberculatus (var. rudis) population from Nebraska, USA with cytochrome P450 inhibitors

Background: A population of Amaranthus tuberculatus (var. rudis) was confirmed resistant to 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibitor herbicides (mesotrione, tembotrione, and topramezone) in a seed corn/soybean rotation in Nebraska. Further investigation confirmed a non-target-site resistance mechanism in this population. The main objective of this study was to explore the role of cytochrome P450 inhibitors in restoring the efficacy of HPPD-inhibitor herbicides on the HPPD-inhibitor resistant A. tuberculatus population from Nebraska, USA (HPPD-R). Background: A population of Amaranthus tuberculatus (var. rudis) was confirmed resistant to 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibitor herbicides (mesotrione, tembotrione, and topramezone) in a seed corn/soybean rotation in Nebraska. Further investigation confirmed a non-target-site resistance mechanism in this population. The main objective of this study was to explore the role of cytochrome P450 inhibitors in restoring the efficacy of HPPD-inhibitor herbicides on the HPPD-inhibitor resistant A. tuberculatus population from Nebraska, USA (HPPD-R). Results: Enhanced metabolism via cytochrome P450 enzymes is the mechanism of resistance in HPPD-R. Amitrole partially restored the activity of mesotrione, whereas malathion, amitrole, and piperonyl butoxide restored the activity of tembotrione and topramezone in HPPD-R. Although corn was injured through malathion followed by mesotrione application a week after treatment, the injury was transient, and the crop recovered. Includes supplementary file