1,718 research outputs found
The spectrum of the random environment and localization of noise
We consider random walk on a mildly random environment on finite transitive
d- regular graphs of increasing girth. After scaling and centering, the
analytic spectrum of the transition matrix converges in distribution to a
Gaussian noise. An interesting phenomenon occurs at d = 2: as the limit graph
changes from a regular tree to the integers, the noise becomes localized.Comment: 18 pages, 1 figur
Conductivity sum rule, implication for in-plane dynamics and c-axis response
Recently observed -axis optical sum rule violations indicate non-Fermi
liquid in-plane behavior. For coherent -axis coupling, the observed flat,
nearly frequency independent -axis conductivity implies
a large in-plane scattering rate around and therefore any
pseudogap that might form at low frequency in the normal state will be smeared.
On the other hand incoherent -axis coupling places no restriction on the
value of and gives a more consistent picture of the observed sum rule
violation which, we find in some cases, can be less than half.Comment: 3 figures. To appear in PR
Radiative Corrections for Pion Polarizability Experiments
We use the semi-analytical program RCFORGV to evaluate radiative corrections
to one-photon radiative emission in the high-energy scattering of pions in the
Coulomb field of a nucleus with atomic number Z. It is shown that radiative
corrections can simulate a pion polarizability effect. The average effect was
estimated for pion energies 40-600 GeV. We also study the range of
applicability of the equivalent photon approximation in describing one-photon
radiative emission.Comment: 11 pages (LaTex), 6 figures, 1 table. No changes in the paper. New
submission because old files are corrupted in arXi
An experimental measurement of corona discharge using laser Dopplervelocimetry
A point to plane testing discharge system was constructed allowing the flow of air to pass, circulate and return to its initial status, when corona is initiated by the alternating applied voltage on the stressed electrode. The corona wind velocity was measured by means of a laser Doppler velocimetry system implemented and calibrated in the laboratory. The velocity measurement was carried out without disturbing the field configuration intensity or the wind flow. The direction and pattern of the corona electric wind was visualized and observed through a laser curtain; this was achieved by guiding smoke to the discharge medium near the stressed electrode. Velocity measurements were obtained for various radial distances r, taken on the central discharge axis for several inter-electrode distances b. The direct observation of the obtained data shows an increase of the corona wind velocity with the applied voltage and the corona discharge current and substantial decrease as the radial distance is enlarged. An experimental investigation was conducted in the research laboratory to use electric wind corona discharge and enhance the available information supporting the corona discharge and applied voltage relationship along with the geometrical system parameter
The STAT5 transcription factor in B-cells of patients with chronic lymphocytic leukemia
Aim. To find out the cause of inhibition of the IL2-STAT5 signaling pathway in chronic lymphocytic leukemia (CLL) cells. Methods.CLL cells were isolated from peripheral blood, using gradient centrifugation on a ficoll-verografin mixture. Expression of the STAT1-6 genes at the mRNA level was analyzed, using the Oncomine database. Expression, phosphorylation status and cellular localization of the STAT5 protein were studied by fluorescence microscopy, using specific antibodies. Results.Unlike B-cells of healthy donors, expression of the STAT5A protein was low in the patient CLL cells. As we have previously shown, the IL-2-STAT5 (JAK-STAT5) signaling pathway is inhibited in CLL cells. Now we demonstrated a low level of phosphorylation of the STAT5 protein, or a complete lack of phosphorylation in CLL cells. The STAT5A protein shows cytoplasmic localization, indicating the absence of complexes in the nucleus that activate/repress transcription of the STAT5-dependent genes. Conclusions. Inhibition of the IL-2-STAT5 pathway in CLL cells is caused by a lack of the STAT5 proteins phosphorylation and/or the absence of the active STAT5A transcription complexes in the nucleus of CLL cells.ΠΠ΅ΡΠ°. ΠΡΡΠ°Π½ΠΎΠ²ΠΈΡΠΈ ΠΏΡΠΈΡΠΈΠ½Ρ Π±Π»ΠΎΠΊΡΠ²Π°Π½Π½Ρ ΡΠΈΠ³Π½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ»ΡΡ
Ρ IL2-STAT5 Ρ ΠΊΠ»ΡΡΠΈΠ½Π°Ρ
ΠΊΡΠΎΠ²Ρ Ρ
Π²ΠΎΡΠΈΡ
Π½Π° Ρ
ΡΠΎΠ½ΡΡΠ½ΠΈΠΉ Π»ΡΡΠΌΠΎΠ»Π΅ΠΉΠΊΠΎΠ· (Π₯ΠΠ). ΠΠ΅ΡΠΎΠ΄ΠΈ. ΠΠ»ΡΡΠΈΠ½ΠΈ Π₯ΠΠ Π²ΠΈΠ΄ΡΠ»ΡΠ»ΠΈ Π· ΠΏΠ΅ΡΠΈΡΠ΅ΡΠΈΡΠ½ΠΎΡ ΠΊΡΠΎΠ²Ρ ΠΏΠ°ΡΡΡΠ½ΡΡΠ², Ρ
Π²ΠΎΡΠΈΡ
Π½Π° Π₯ΠΠ, Π·Π° Π΄ΠΎΠΏΠΎΠΌΠΎΠ³ΠΎΡ ΡΠ΅Π½ΡΡΠΈΡΡΠ³ΡΠ²Π°Π½Π½Ρ Ρ Π³ΡΠ°Π΄ΡΡΠ½ΡΡΡΡΠΊΠΎΠ»-Π²Π΅ΡΠΎΠ³ΡΠ°ΡΡΠ½. ΠΠΊΡΠΏΡΠ΅ΡΡΡ Π³Π΅Π½ΡΠ² STAT1-6 Π½Π° ΡΡΠ²Π½Ρ ΠΌΠ ΠΠ Π°Π½Π°Π»ΡΠ·ΡΠ²Π°Π»ΠΈ Π·Π° Π΄ΠΎΠΏΠΎΠΌΠΎΠ³ΠΎΡ Π±Π°Π·ΠΈ Π΄Π°Π½ΠΈΡ
Oncomine. ΠΠΊΡΠΏΡΠ΅ΡΡΡ, ΡΡΠ°ΡΡΡ ΡΠΎΡΡΠΎΡΠΈΠ»ΡΠ²Π°Π½Π½Ρ Ρ ΠΊΠ»ΡΡΠΈΠ½Π½Ρ Π»ΠΎΠΊΠ°Π»ΡΠ·Π°ΡΡΡ Π±ΡΠ»ΠΊΠ° STAT5 Π²ΠΈΠ²ΡΠ°Π»ΠΈ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΠΎΡ ΠΌΡΠΊΡΠΎΡΠΊΠΎΠΏΡΡ Π· Π²ΠΈΠΊΠΎΡΠΈΡΡΠ°Π½Π½ΡΠΌ ΡΠΏΠ΅ΡΠΈΡΡΡΠ½ΠΈΡ
Π°Π½ΡΠΈΡΡΠ». Π Π΅Π·ΡΠ»ΡΡΠ°ΡΠΈ. ΠΠ°Π²ΡΠ΄ΠΌΡΠ½ΡΠ²ΡΠ΄ Π-ΠΊΠ»ΡΡΠΈΠ½ Π·Π΄ΠΎΡΠΎΠ²ΠΈΡ
Π»ΡΠ΄Π΅ΠΉ, Π΅ΠΊΡΠΏΡΠ΅ΡΡΡ Π±ΡΠ»ΠΊΠ° STAT5Π Π±ΡΠ»Π° Π½ΠΈΠ·ΡΠΊΠΎΡ Ρ ΠΊΠ»ΡΡΠΈΠ½Π°Ρ
Ρ
Π²ΠΎΡΠΈΡ
Π½Π° Π₯ΠΠ. Π―ΠΊ Π½Π°ΠΌΠΈ Π±ΡΠ»ΠΎ Π²ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ ΡΠ°Π½ΡΡΠ΅, ΡΠΈΠ³Π½Π°Π»ΡΠ½ΠΈΠΉ ΡΠ»ΡΡ
IL-2-STAT5 (JAK-STAT5) ΡΠ½Π³ΡΠ±ΠΎΠ²Π°Π½ΠΎ Ρ ΠΊΠ»ΡΡΠΈΠ½Π°Ρ
Π₯ΠΠ. ΠΠ°ΠΌΠΈ Π±ΡΠ»ΠΎ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ Π½ΠΈΠ·ΡΠΊΠΈΠΉ ΡΡΠ²Π΅Π½Ρ ΡΠΎΡΡΠΎΡΠΈΠ»ΡΠ²Π°Π½Π½Ρ Π±ΡΠ»ΠΊΡΠ² STAT5, Π°Π±ΠΎ ΠΏΠΎΠ²Π½Ρ Π²ΡΠ΄ΡΡΡΠ½ΡΡΡΡ ΡΠΎΡΡΠΎΡΠΈΠ»ΡΠΎΠ²Π°Π½ΠΎΡ ΡΠΎΡΠΌΠΈ ΠΏΡΠΎΡΠ΅ΡΠ½ΡΠ² Π² Π»Π΅ΠΉΠΊΠ΅ΠΌΡΡΠ½ΠΈΡ
ΠΊΠ»ΡΡΠΈΠ½Π°Ρ
. ΠΡΠΎΡΠ΅ΡΠ½ STAT5Π ΠΏΠΎΠΊΠ°Π·ΡΡ ΡΠΈΡΠΎΠΏΠ»Π°Π·ΠΌΠ°ΡΠΈΡΠ½Ρ Π»ΠΎΠΊΠ°Π»ΡΠ·Π°ΡΡΡ, ΡΠΎ Π²ΠΊΠ°Π·ΡΡ Π½ Π°Π²ΡΠ΄ΡΡΡΠ½ΡΡΡΡ Ρ ΡΠ΄ΡΡΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΡΠ², Π°ΠΊΡΠΈΠ²ΡΡΡΠΈΡ
ΡΡΠ°Π½ΡΠΊΡΠΈΠΏΡΡΡ Π³Π΅Π½ΡΠ², Π·Π°Π»Π΅ΠΆΠ½ΠΈΡ
Π²ΡΠ΄ ΡΠ°ΠΊΡΠΎΡΠ° ΡΡΠ°Π½ΡΠΊΡΠΈΠΏΡΡΡ STAT5. ΠΠΈΡΠ½ΠΎΠ²ΠΊΠΈ. ΠΠ½Π³ΠΈΠ±ΡΠ²Π°Π½Π½Ρ ΡΠΈΠ³Π½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΊΠ»ΡΡΠΈΠ½Π½ΠΎΠ³ΠΎ ΡΠ»ΡΡ
Ρ IL-2-STAT5 Π² ΠΊΠ»ΡΡΠΈΠ½Π°Ρ
ΠΊΡΠΎΠ²Ρ Ρ
Π²ΠΎΡΠΈΡ
Π½Π° Π₯ΠΠ ΡΠ΅Π°Π»ΡΠ·ΡΡΡΡΡΡ Π·Π° ΡΠ°Ρ
ΡΠ½ΠΎΠΊ Π³ΡΠΏΠΎΡΠΎΡΡΠΎΡΠΈΠ»ΡΠ²Π°Π½Π½Ρ ΠΏΡΠΎΡΠ΅ΡΠ½ΡΠ² STAT5 ΡΠ°/Π°Π±ΠΎ Π²ΡΠ΄ΡΡΡΠ½ΠΎΡΡΡ Π°ΠΊΡΠΈΠ²Π½ΠΈΡ
ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΡΠ² ΡΡΠ°Π½ΡΠΊΡΠΈΠΏΡΡΡ STAT5Π Ρ ΡΠ΄ΡΡ Π»Π΅ΠΉΠΊΠ΅ΠΌΠΈΡΠ½ΠΈΡ
ΠΊΠ»ΡΡΠΈΠ½.Π¦Π΅Π»Ρ. Π£ΡΡΠ°Π½ΠΎΠ²ΠΈΡΡ ΠΏΡΠΈΡΠΈΠ½Ρ Π±Π»ΠΎΠΊΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠΈΠ³Π½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΡΡΠΈ IL2-STAT5 Π² ΠΊΠ»Π΅ΡΠΊΠ°Ρ
ΠΊΡΠΎΠ²ΠΈ Π±ΠΎΠ»ΡΠ½ΡΡ
Ρ
ΡΠΎΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΌ Π»ΠΈΠΌΡΠΎΠ»Π΅ΠΉΠΊΠΎΠ·ΠΎΠΌ (Π₯ΠΠ). ΠΠ΅ΡΠΎΠ΄Ρ. ΠΠ΅ΠΉΠΊΠ΅ΠΌΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΊΠ»Π΅ΡΠΊΠΈ Π²ΡΠ΄Π΅Π»ΡΠ»ΠΈ ΠΈΠ· ΠΏΠ΅ΡΠΈΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΊΡΠΎΠ²ΠΈ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΡΠ΅Π½ΡΡΠΈΡΡΠ³ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π² Π³ΡΠ°Π΄ΠΈΠ΅Π½ΡΠ΅ ΠΏΠ»ΠΎΡΠ½ΠΎΡΡΠΈ ΡΠΈΠΊΠΎΠ»Π»-Π²Π΅ΡΠΎΠ³ΡΠ°ΡΠΈΠ½. ΠΠΊΡΠΏΡΠ΅ΡΡΠΈΡ Π³Π΅Π½ΠΎΠ² STAT1-6 Π½Π° ΡΡΠΎΠ²Π½Π΅ ΠΌΠ ΠΠ Π°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π»ΠΈ Ρ ΠΏΠΎΠΌΠΎΡΡΡ Π±Π°Π·Ρ Π΄Π°Π½Π½ΡΡ
Oncomine. ΠΠΊΡΠΏΡΠ΅ΡΡΠΈΡ, ΡΡΠ°ΡΡΡ ΡΠΎΡΡΠΎΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΈ ΠΊΠ»Π΅ΡΠΎΡΠ½ΡΡ Π»ΠΎΠΊΠ°Π»ΠΈΠ·Π°ΡΠΈΡ Π±Π΅Π»ΠΊΠ° STAT5 ΠΈΠ·ΡΡΠ°Π»ΠΈ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ ΡΠ»ΡΠΎΡΠ΅ΡΡΠ΅Π½ΡΠ½ΠΎΠΉ ΠΌΠΈΠΊΡΠΎΡΠΊΠΎΠΏΠΈΠΈ Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΡΠΏΠ΅ΡΠΈΡΠΈΡΠ΅ΡΠΊΠΈΡ
Π°Π½ΡΠΈΡΠ΅Π». Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π ΠΎΡΠ»ΠΈΡΠΈΠ΅ ΠΎΡ Π-ΠΊΠ»Π΅ΡΠΎΠΊ Π·Π΄ΠΎΡΠΎΠ²ΡΡ
Π»ΡΠ΄Π΅ΠΉ, ΡΠΊΡΠΏΡΠ΅ΡΡΠΈΡ Π±Π΅Π»ΠΊΠ° STAT5Π Π±ΡΠ»Π° Π½ΠΈΠ·ΠΊΠΎΠΉ Π² ΠΊΠ»Π΅ΡΠΊΠ°Ρ
Π±ΠΎΠ»ΡΠ½ΡΡ
Π₯ΠΠ. ΠΠ°ΠΊ Π½Π°ΠΌΠΈ Π±ΡΠ»ΠΎ ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ ΡΠ°Π½Π΅Π΅, ΡΠΈΠ³Π½Π°Π»ΡΠ½ΡΠΉ ΠΏΡΡΡ IL-2-STAT5 (JAK-STAT5) ΠΈΠ½Π³ΠΈΠ±ΠΈΡΠΎΠ²Π°Π½ Π² ΠΊΠ»Π΅ΡΠΊΠ°Ρ
Π₯ΠΠ. ΠΠ°ΠΌΠΈΠ±ΡΠ»ΠΏΠΎΠΊΠ°Π·Π°Π½Π½ΠΈΠ·ΠΊΠΈΠΉΡΡΠΎΠ²Π΅Π½ΡΡΠΎΡΡΠΎΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡΠ±Π΅Π»ΠΊΠΎΠ² STAT5 ΠΈΠ»ΠΈ ΠΏΠΎΠ»Π½ΠΎΠ΅ ΠΎΡΡΡΡΡΡΠ²ΠΈΠ΅ ΡΠΎΡΡΠΎΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠΉ ΡΠΎΡΠΌΡ ΠΏΡΠΎΡΠ΅ΠΈΠ½ΠΎΠ² Π² Π»Π΅ΠΉΠΊΠ΅ΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΊΠ»Π΅ΡΠΊΠ°Ρ
. ΠΡΠΎΡΠ΅ΠΈΠ½ STAT5Π ΠΏΠΎΠΊΠ°Π·ΡΠ²Π°Π΅Ρ ΡΠΈΡΠΎΠΏΠ»Π°Π·ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΡΡ Π»ΠΎΠΊΠ°Π»ΠΈΠ·Π°ΡΠΈΡ, ΡΡΠΎ ΡΠΊΠ°Π·ΡΠ²Π°Π΅Ρ Π½Π° ΠΎΡΡΡΡΡΡΠ²ΠΈΠ΅ Π² ΡΠ΄ΡΠ΅ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠΎΠ², Π°ΠΊΡΠΈΠ²ΠΈΡΡΡΡΠΈΡ
ΡΡΠ°Π½ΡΠΊΡΠΈΠΏΡΠΈΡ Π³Π΅Π½ΠΎΠ², Π·Π°Π²ΠΈΡΠΈΠΌΡΡ
ΠΎΡ ΡΠ°ΠΊΡΠΎΡΠ° ΡΡΠ°Π½ΡΠΊΡΠΈΠΏΡΠΈΠΈ STAT5. ΠΡΠ²ΠΎΠ΄Ρ. ΠΠ½Π³ΠΈΠ±ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠΈΠ³Π½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΊΠ»Π΅ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΏΡΡΠΈ IL-2-STAT5 Π² ΠΊΠ»Π΅ΡΠΊΠ°Ρ
ΠΊΡΠΎΠ²ΠΈ Π±ΠΎΠ»ΡΠ½ΡΡ
Π₯ΠΠ ΠΏΡΠΎΠΈΡΡ
ΠΎΠ΄ΠΈΡ Π·Π° ΡΡΡΡ Π³ΠΈΠΏΠΎΡΠΎΡΡΠΎΡΠΈΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π±Π΅Π»ΠΊΠΎΠ² STAT5 ΠΈ/ΠΈΠ»ΠΈ ΠΎΡΡΡΡΡΡΠ²ΠΈΡ Π°ΠΊΡΠΈΠ²Π½ΡΡ
ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠΎΠ² ΡΡΠ°Π½ΡΠΊΡΠΈΠΏΡΠΈΠΈ STAT5Π Π² ΡΠ΄ΡΠ΅ Π»Π΅ΠΉΠΊΠ΅ΠΌΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΊΠ»Π΅ΡΠΎΠΊ
Multiplicativity of completely bounded p-norms implies a new additivity result
We prove additivity of the minimal conditional entropy associated with a
quantum channel Phi, represented by a completely positive (CP),
trace-preserving map, when the infimum of S(gamma_{12}) - S(gamma_1) is
restricted to states of the form gamma_{12} = (I \ot Phi)(| psi >< psi |). We
show that this follows from multiplicativity of the completely bounded norm of
Phi considered as a map from L_1 -> L_p for L_p spaces defined by the Schatten
p-norm on matrices; we also give an independent proof based on entropy
inequalities. Several related multiplicativity results are discussed and
proved. In particular, we show that both the usual L_1 -> L_p norm of a CP map
and the corresponding completely bounded norm are achieved for positive
semi-definite matrices. Physical interpretations are considered, and a new
proof of strong subadditivity is presented.Comment: Final version for Commun. Math. Physics. Section 5.2 of previous
version deleted in view of the results in quant-ph/0601071 Other changes
mino
Observation of microwave radiation using low-cost detectors at the anka storage ring
Synchrotron light sources emit Coherent Synchrotron Radiation (CSR) for wavelengths longer than or equal to the bunch length. At most storage rings CSR cannot be observed, because the vacuum chamber cuts off radiation with long wavelengths. There are different approaches for shifting the CSR to shorter wavelengths that can propagate through the beam pipe, e.g.: the accelerator optics can be optimized for a low momentum compaction factor, thus reducing the bunch length. Alternatively, laser slicing can modulate substructures on long bunches [1]. Both techniques extend the CSR spectrum to shorter wavelengths, so that CSR is emitted at wavelengths below the waveguide shielding cut off. Usually fast detectors, like superconducting bolometer detector systems or Schottky barrier diodes, are used for observation of dynamic processes in accelerator physics. In this paper, we present observations of microwave radiation at ANKA using an alternative detector, a LNB (Low Noise Block) system. These devices are usually used in standard TV-SAT-receivers and are very cheap. We determined the time response of LNBs to be below 100 ns. The sensitivity of LNBs is optimized to detect very low intensity βnoise-likeβ signals. This microwave radiation study shows the possibility to apply the LNB for bunch length monitoring
- β¦