1,718 research outputs found

    The spectrum of the random environment and localization of noise

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    We consider random walk on a mildly random environment on finite transitive d- regular graphs of increasing girth. After scaling and centering, the analytic spectrum of the transition matrix converges in distribution to a Gaussian noise. An interesting phenomenon occurs at d = 2: as the limit graph changes from a regular tree to the integers, the noise becomes localized.Comment: 18 pages, 1 figur

    INDEXES TO 708 UNCLASSIFIED DOCUMENTS ON CIVIL DEFENSE.

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    Conductivity sum rule, implication for in-plane dynamics and c-axis response

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    Recently observed cc-axis optical sum rule violations indicate non-Fermi liquid in-plane behavior. For coherent cc-axis coupling, the observed flat, nearly frequency independent cc-axis conductivity Οƒ1(Ο‰)\sigma_{1}(\omega) implies a large in-plane scattering rate Ξ“\Gamma around (0,Ο€)(0,\pi) and therefore any pseudogap that might form at low frequency in the normal state will be smeared. On the other hand incoherent cc-axis coupling places no restriction on the value of Ξ“\Gamma and gives a more consistent picture of the observed sum rule violation which, we find in some cases, can be less than half.Comment: 3 figures. To appear in PR

    Radiative Corrections for Pion Polarizability Experiments

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    We use the semi-analytical program RCFORGV to evaluate radiative corrections to one-photon radiative emission in the high-energy scattering of pions in the Coulomb field of a nucleus with atomic number Z. It is shown that radiative corrections can simulate a pion polarizability effect. The average effect was estimated for pion energies 40-600 GeV. We also study the range of applicability of the equivalent photon approximation in describing one-photon radiative emission.Comment: 11 pages (LaTex), 6 figures, 1 table. No changes in the paper. New submission because old files are corrupted in arXi

    An experimental measurement of corona discharge using laser Dopplervelocimetry

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    A point to plane testing discharge system was constructed allowing the flow of air to pass, circulate and return to its initial status, when corona is initiated by the alternating applied voltage on the stressed electrode. The corona wind velocity was measured by means of a laser Doppler velocimetry system implemented and calibrated in the laboratory. The velocity measurement was carried out without disturbing the field configuration intensity or the wind flow. The direction and pattern of the corona electric wind was visualized and observed through a laser curtain; this was achieved by guiding smoke to the discharge medium near the stressed electrode. Velocity measurements were obtained for various radial distances r, taken on the central discharge axis for several inter-electrode distances b. The direct observation of the obtained data shows an increase of the corona wind velocity with the applied voltage and the corona discharge current and substantial decrease as the radial distance is enlarged. An experimental investigation was conducted in the research laboratory to use electric wind corona discharge and enhance the available information supporting the corona discharge and applied voltage relationship along with the geometrical system parameter

    The STAT5 transcription factor in B-cells of patients with chronic lymphocytic leukemia

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    Aim. To find out the cause of inhibition of the IL2-STAT5 signaling pathway in chronic lymphocytic leukemia (CLL) cells. Methods.CLL cells were isolated from peripheral blood, using gradient centrifugation on a ficoll-verografin mixture. Expression of the STAT1-6 genes at the mRNA level was analyzed, using the Oncomine database. Expression, phosphorylation status and cellular localization of the STAT5 protein were studied by fluorescence microscopy, using specific antibodies. Results.Unlike B-cells of healthy donors, expression of the STAT5A protein was low in the patient CLL cells. As we have previously shown, the IL-2-STAT5 (JAK-STAT5) signaling pathway is inhibited in CLL cells. Now we demonstrated a low level of phosphorylation of the STAT5 protein, or a complete lack of phosphorylation in CLL cells. The STAT5A protein shows cytoplasmic localization, indicating the absence of complexes in the nucleus that activate/repress transcription of the STAT5-dependent genes. Conclusions. Inhibition of the IL-2-STAT5 pathway in CLL cells is caused by a lack of the STAT5 proteins phosphorylation and/or the absence of the active STAT5A transcription complexes in the nucleus of CLL cells.ΠœΠ΅Ρ‚Π°. Встановити ΠΏΡ€ΠΈΡ‡ΠΈΠ½Ρƒ блокування сигнального ΡˆΠ»ΡΡ…Ρƒ IL2-STAT5 Ρƒ ΠΊΠ»Ρ–Ρ‚ΠΈΠ½Π°Ρ… ΠΊΡ€ΠΎΠ²Ρ– Ρ…Π²ΠΎΡ€ΠΈΡ… Π½Π° Ρ…Ρ€ΠΎΠ½Ρ–Ρ‡Π½ΠΈΠΉ Π»Ρ–Ρ„ΠΌΠΎΠ»Π΅ΠΉΠΊΠΎΠ· (Π₯Π›Π›). ΠœΠ΅Ρ‚ΠΎΠ΄ΠΈ. ΠšΠ»Ρ–Ρ‚ΠΈΠ½ΠΈ Π₯Π›Π› виділяли Π· ΠΏΠ΅Ρ€ΠΈΡ„Π΅Ρ€ΠΈΡ‡Π½ΠΎΡ— ΠΊΡ€ΠΎΠ²Ρ– ΠΏΠ°Ρ†Ρ–Ρ”Π½Ρ‚Ρ–Π², Ρ…Π²ΠΎΡ€ΠΈΡ… Π½Π° Π₯Π›Π›, Π·Π° допомогою цСнтрифугування Ρƒ Π³Ρ€Π°Π΄Ρ–Ρ”Π½Ρ‚Ρ–Ρ„Ρ–ΠΊΠΎΠ»-Π²Π΅Ρ€ΠΎΠ³Ρ€Π°Ρ„Ρ–Π½. Π•ΠΊΡΠΏΡ€Π΅ΡΡ–ΡŽ Π³Π΅Π½Ρ–Π² STAT1-6 Π½Π° Ρ€Ρ–Π²Π½Ρ– мРНК Π°Π½Π°Π»Ρ–Π·ΡƒΠ²Π°Π»ΠΈ Π·Π° допомогою Π±Π°Π·ΠΈ Π΄Π°Π½ΠΈΡ… Oncomine. Π•ΠΊΡΠΏΡ€Π΅ΡΡ–ΡŽ, статус Ρ„ΠΎΡΡ„ΠΎΡ€ΠΈΠ»ΡŽΠ²Π°Π½Π½Ρ Ρ– ΠΊΠ»Ρ–Ρ‚ΠΈΠ½Π½Ρƒ Π»ΠΎΠΊΠ°Π»Ρ–Π·Π°Ρ†Ρ–ΡŽ Π±Ρ–Π»ΠΊΠ° STAT5 Π²ΠΈΠ²Ρ‡Π°Π»ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ флуорСсцСнтної мікроскопії Π· використаннім спСцифічних Π°Π½Ρ‚ΠΈΡ‚Ρ–Π». Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΈ. Навідмінувід Π’-ΠΊΠ»Ρ–Ρ‚ΠΈΠ½ Π·Π΄ΠΎΡ€ΠΎΠ²ΠΈΡ… людСй, СкспрСсія Π±Ρ–Π»ΠΊΠ° STAT5А Π±ΡƒΠ»Π° низькою Ρƒ ΠΊΠ»Ρ–Ρ‚ΠΈΠ½Π°Ρ… Ρ…Π²ΠΎΡ€ΠΈΡ… Π½Π° Π₯Π›Π›. Π―ΠΊ Π½Π°ΠΌΠΈ Π±ΡƒΠ»ΠΎ встановлСно Ρ€Π°Π½Ρ–ΡˆΠ΅, сигнальний ΡˆΠ»ΡΡ… IL-2-STAT5 (JAK-STAT5) Ρ–Π½Π³Ρ–Π±ΠΎΠ²Π°Π½ΠΎ Ρƒ ΠΊΠ»Ρ–Ρ‚ΠΈΠ½Π°Ρ… Π₯Π›Π›. Нами Π±ΡƒΠ»ΠΎ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ низький Ρ€Ρ–Π²Π΅Π½ΡŒ Ρ„ΠΎΡΡ„ΠΎΡ€ΠΈΠ»ΡŽΠ²Π°Π½Π½Ρ Π±Ρ–Π»ΠΊΡ–Π² STAT5, Π°Π±ΠΎ ΠΏΠΎΠ²Π½Ρƒ Π²Ρ–Π΄ΡΡƒΡ‚Π½Ρ–ΡΡ‚ΡŒ Ρ„ΠΎΡΡ„ΠΎΡ€ΠΈΠ»ΡŒΠΎΠ²Π°Π½ΠΎΡ— Ρ„ΠΎΡ€ΠΌΠΈ ΠΏΡ€ΠΎΡ‚Π΅Ρ—Π½Ρ–Π² Π² Π»Π΅ΠΉΠΊΠ΅ΠΌΡ–Ρ‡Π½ΠΈΡ… ΠΊΠ»Ρ–Ρ‚ΠΈΠ½Π°Ρ…. ΠŸΡ€ΠΎΡ‚Π΅Ρ—Π½ STAT5А ΠΏΠΎΠΊΠ°Π·ΡƒΡ” Ρ†ΠΈΡ‚ΠΎΠΏΠ»Π°Π·ΠΌΠ°Ρ‚ΠΈΡ‡Π½Ρƒ Π»ΠΎΠΊΠ°Π»Ρ–Π·Π°Ρ†Ρ–ΡŽ, Ρ‰ΠΎ Π²ΠΊΠ°Π·ΡƒΡ” Π½ Π°Π²Ρ–Π΄ΡΡƒΡ‚Π½Ρ–ΡΡ‚ΡŒ Ρƒ ядрікомплСксів, Π°ΠΊΡ‚ΠΈΠ²ΡƒΡŽΡ‡ΠΈΡ… Ρ‚Ρ€Π°Π½ΡΠΊΡ€ΠΈΠΏΡ†Ρ–ΡŽ Π³Π΅Π½Ρ–Π², Π·Π°Π»Π΅ΠΆΠ½ΠΈΡ… Π²Ρ–Π΄ Ρ„Π°ΠΊΡ‚ΠΎΡ€Π° транскрипції STAT5. Висновки. Інгибування сигнального ΠΊΠ»Ρ–Ρ‚ΠΈΠ½Π½ΠΎΠ³ΠΎ ΡˆΠ»ΡΡ…Ρƒ IL-2-STAT5 Π² ΠΊΠ»Ρ–Ρ‚ΠΈΠ½Π°Ρ… ΠΊΡ€ΠΎΠ²Ρ– Ρ…Π²ΠΎΡ€ΠΈΡ… Π½Π° Π₯Π›Π› Ρ€Π΅Π°Π»Ρ–Π·ΡƒΡ”Ρ‚ΡŒΡΡ Π·Π° Ρ€Π°Ρ…ΡƒΠ½ΠΎΠΊ Π³Ρ–ΠΏΠΎΡ„ΠΎΡΡ„ΠΎΡ€ΠΈΠ»ΡŽΠ²Π°Π½Π½Ρ ΠΏΡ€ΠΎΡ‚Π΅Ρ—Π½Ρ–Π² STAT5 Ρ‚Π°/Π°Π±ΠΎ відсутності Π°ΠΊΡ‚ΠΈΠ²Π½ΠΈΡ… комплСксів транскрипції STAT5А Ρƒ ядрі Π»Π΅ΠΉΠΊΠ΅ΠΌΠΈΡ‡Π½ΠΈΡ… ΠΊΠ»Ρ–Ρ‚ΠΈΠ½.ЦСль. Π£ΡΡ‚Π°Π½ΠΎΠ²ΠΈΡ‚ΡŒ ΠΏΡ€ΠΈΡ‡ΠΈΠ½Ρƒ блокирования сигнального ΠΏΡƒΡ‚ΠΈ IL2-STAT5 Π² ΠΊΠ»Π΅Ρ‚ΠΊΠ°Ρ… ΠΊΡ€ΠΎΠ²ΠΈ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… хроничСским Π»ΠΈΠΌΡ„ΠΎΠ»Π΅ΠΉΠΊΠΎΠ·ΠΎΠΌ (Π₯Π›Π›). ΠœΠ΅Ρ‚ΠΎΠ΄Ρ‹. ЛСйкСмичСскиС ΠΊΠ»Π΅Ρ‚ΠΊΠΈ выдСляли ΠΈΠ· пСрифСричСской ΠΊΡ€ΠΎΠ²ΠΈ с ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ цСнтрифугирования Π² Π³Ρ€Π°Π΄ΠΈΠ΅Π½Ρ‚Π΅ плотности Ρ„ΠΈΠΊΠΎΠ»Π»-Π²Π΅Ρ€ΠΎΠ³Ρ€Π°Ρ„ΠΈΠ½. Π­ΠΊΡΠΏΡ€Π΅ΡΡΠΈΡŽ Π³Π΅Π½ΠΎΠ² STAT1-6 Π½Π° ΡƒΡ€ΠΎΠ²Π½Π΅ мРНК Π°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΠΎΠ²Π°Π»ΠΈ с ΠΏΠΎΠΌΠΎΡ‰ΡŒΡŽ Π±Π°Π·Ρ‹ Π΄Π°Π½Π½Ρ‹Ρ… Oncomine. Π­ΠΊΡΠΏΡ€Π΅ΡΡΠΈΡŽ, статус фосфорилирования ΠΈ ΠΊΠ»Π΅Ρ‚ΠΎΡ‡Π½ΡƒΡŽ Π»ΠΎΠΊΠ°Π»ΠΈΠ·Π°Ρ†ΠΈΡŽ Π±Π΅Π»ΠΊΠ° STAT5 ΠΈΠ·ΡƒΡ‡Π°Π»ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ флуорСсцСнтной микроскопии с использованиСм спСцифичСских Π°Π½Ρ‚ΠΈΡ‚Π΅Π». Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. Π’ ΠΎΡ‚Π»ΠΈΡ‡ΠΈΠ΅ ΠΎΡ‚ Π’-ΠΊΠ»Π΅Ρ‚ΠΎΠΊ Π·Π΄ΠΎΡ€ΠΎΠ²Ρ‹Ρ… людСй, экспрСссия Π±Π΅Π»ΠΊΠ° STAT5А Π±Ρ‹Π»Π° Π½ΠΈΠ·ΠΊΠΎΠΉ Π² ΠΊΠ»Π΅Ρ‚ΠΊΠ°Ρ… Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… Π₯Π›Π›. Как Π½Π°ΠΌΠΈ Π±Ρ‹Π»ΠΎ установлСно Ρ€Π°Π½Π΅Π΅, ΡΠΈΠ³Π½Π°Π»ΡŒΠ½Ρ‹ΠΉ ΠΏΡƒΡ‚ΡŒ IL-2-STAT5 (JAK-STAT5) ΠΈΠ½Π³ΠΈΠ±ΠΈΡ€ΠΎΠ²Π°Π½ Π² ΠΊΠ»Π΅Ρ‚ΠΊΠ°Ρ… Π₯Π›Π›. ΠΠ°ΠΌΠΈΠ±Ρ‹Π»ΠΏΠΎΠΊΠ°Π·Π°Π½Π½ΠΈΠ·ΠΊΠΈΠΉΡƒΡ€ΠΎΠ²Π΅Π½ΡŒΡ„ΠΎΡΡ„ΠΎΡ€ΠΈΠ»ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΡΠ±Π΅Π»ΠΊΠΎΠ² STAT5 ΠΈΠ»ΠΈ ΠΏΠΎΠ»Π½ΠΎΠ΅ отсутствиС фосфорилированной Ρ„ΠΎΡ€ΠΌΡ‹ ΠΏΡ€ΠΎΡ‚Π΅ΠΈΠ½ΠΎΠ² Π² лСйкСмичСских ΠΊΠ»Π΅Ρ‚ΠΊΠ°Ρ…. ΠŸΡ€ΠΎΡ‚Π΅ΠΈΠ½ STAT5А ΠΏΠΎΠΊΠ°Π·Ρ‹Π²Π°Π΅Ρ‚ Ρ†ΠΈΡ‚ΠΎΠΏΠ»Π°Π·ΠΌΠ°Ρ‚ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ Π»ΠΎΠΊΠ°Π»ΠΈΠ·Π°Ρ†ΠΈΡŽ, Ρ‡Ρ‚ΠΎ ΡƒΠΊΠ°Π·Ρ‹Π²Π°Π΅Ρ‚ Π½Π° отсутствиС Π² ядрС комплСксов, Π°ΠΊΡ‚ΠΈΠ²ΠΈΡ€ΡƒΡŽΡ‰ΠΈΡ… Ρ‚Ρ€Π°Π½ΡΠΊΡ€ΠΈΠΏΡ†ΠΈΡŽ Π³Π΅Π½ΠΎΠ², зависимых ΠΎΡ‚ Ρ„Π°ΠΊΡ‚ΠΎΡ€Π° транскрипции STAT5. Π’Ρ‹Π²ΠΎΠ΄Ρ‹. Π˜Π½Π³ΠΈΠ±ΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠ΅ сигнального ΠΊΠ»Π΅Ρ‚ΠΎΡ‡Π½ΠΎΠ³ΠΎ ΠΏΡƒΡ‚ΠΈ IL-2-STAT5 Π² ΠΊΠ»Π΅Ρ‚ΠΊΠ°Ρ… ΠΊΡ€ΠΎΠ²ΠΈ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… Π₯Π›Π› происходит Π·Π° счёт гипофосфорилирования Π±Π΅Π»ΠΊΠΎΠ² STAT5 ΠΈ/ΠΈΠ»ΠΈ отсутствия Π°ΠΊΡ‚ΠΈΠ²Π½Ρ‹Ρ… комплСксов транскрипции STAT5А Π² ядрС лСйкСмичСских ΠΊΠ»Π΅Ρ‚ΠΎΠΊ

    Multiplicativity of completely bounded p-norms implies a new additivity result

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    We prove additivity of the minimal conditional entropy associated with a quantum channel Phi, represented by a completely positive (CP), trace-preserving map, when the infimum of S(gamma_{12}) - S(gamma_1) is restricted to states of the form gamma_{12} = (I \ot Phi)(| psi >< psi |). We show that this follows from multiplicativity of the completely bounded norm of Phi considered as a map from L_1 -> L_p for L_p spaces defined by the Schatten p-norm on matrices; we also give an independent proof based on entropy inequalities. Several related multiplicativity results are discussed and proved. In particular, we show that both the usual L_1 -> L_p norm of a CP map and the corresponding completely bounded norm are achieved for positive semi-definite matrices. Physical interpretations are considered, and a new proof of strong subadditivity is presented.Comment: Final version for Commun. Math. Physics. Section 5.2 of previous version deleted in view of the results in quant-ph/0601071 Other changes mino

    Observation of microwave radiation using low-cost detectors at the anka storage ring

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    Synchrotron light sources emit Coherent Synchrotron Radiation (CSR) for wavelengths longer than or equal to the bunch length. At most storage rings CSR cannot be observed, because the vacuum chamber cuts off radiation with long wavelengths. There are different approaches for shifting the CSR to shorter wavelengths that can propagate through the beam pipe, e.g.: the accelerator optics can be optimized for a low momentum compaction factor, thus reducing the bunch length. Alternatively, laser slicing can modulate substructures on long bunches [1]. Both techniques extend the CSR spectrum to shorter wavelengths, so that CSR is emitted at wavelengths below the waveguide shielding cut off. Usually fast detectors, like superconducting bolometer detector systems or Schottky barrier diodes, are used for observation of dynamic processes in accelerator physics. In this paper, we present observations of microwave radiation at ANKA using an alternative detector, a LNB (Low Noise Block) system. These devices are usually used in standard TV-SAT-receivers and are very cheap. We determined the time response of LNBs to be below 100 ns. The sensitivity of LNBs is optimized to detect very low intensity ”noise-like” signals. This microwave radiation study shows the possibility to apply the LNB for bunch length monitoring
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