Polypropylene Hollow Fiber Oxygenators: Effect Of The Sorption Of Perfluoropolyethers

The introduction of microporous polypropylene hollow fibers in recent years has brought considerable advances to blood oxygenators. However, lifetime and assembly problems are still unresolved. In this work we tried to rate the oxygen permeation velocity by turning the fibers more hydrophobic through the sorption of a perfluorocarbon. Fomblin HC/25, a perfluoropolyether, is well known for its low surface tension and high affinity for oxygen. Celgard X10, X20, and X30 commercial hollow fibers were tested. The hollow fibers showed high affinity for the perfluoropolyether; swelling was clearly shown. A new system for the measurement of oxygen permeation velocity was developed. The oxygen transport velocity was not significantly changed after sorption. The Celgard microporous hollow fibers impregnated with perfluoropolyether showed no water permeation after 2 months of use, reducing one of the most serious problems in the lifetime of these types of fibers.243168173Voorhees, M.E., Oxygenator technology: The future (1994) Perfusion, 9, pp. 229-232Montoya, J.P., Shanley, C.J., Merz, S.I., Bartlett, R.H., Plasma leakage through microporous membranes: Role of phospholipids (1992) Asaio J, 38, pp. M399-405Cheng, B.T., Leonard, E.F., Light microscopic visualization of plasma intrusion into microporous hollow fiber (1995) ASAIO J, 41, pp. 863-872Lund, L.W., Federspiel, W.J., Hattler, B.G., Gas permeability of hollow fiber membranes in a gas-liquid system (1996) J Membrane Science, 117, pp. 207-219Gaylor, J.D.S., Membrane oxygenators: Influence of design on performance (1994) Perfusion, 9, pp. 173-180Qi, Z., Microporous hollow fibers for gas absorption: II. Mass transfer across the membrane (1985) J Membrane Science, 23, pp. 333-345Costello, M.J., Fane, A.G., Hogan, P.A., Schofield, R.W., The effect of shell side hydrodynamics on the performance of axial flow hollow fiber modules (1993) J Membrane Science, 80, pp. 1-11Wickramasinghe, S.R., Semmens, M.J., Cussler, E.L., Mass transfer in various hollow fiber geometries (1992) J Membrane Science, 69, pp. 235-250Yasuda, H., Lamaze, C.F., Transfer of gas to dissolved oxygen in water via porous and nonporous polymer membrane J Appl Poly Science, 16, pp. 595-601. , 1072Kamo, J., Uchida, M., Hirai, T., Yasida, H., Kanada, K., Takemura, T., A new multilayered composite hollow fiber membrane for artificial lung (1990) Artif Organs, 14 (5), pp. 369-372Yamanouchi, K., Heldebrant, C., Perfluorochemicals as a blood substitute (1992) Chemtech, JUNE, pp. 354-359Rüdiger, S., Methods for forecasting the usefulness of perfluorocarbons for blood substitutes (1989) J Fluorine Chemistry, 42, pp. 403-412Lawson, D.D., Moacanin, J., Scherer, K.V., Terranova T.F., Jr., Inghan, J.D., Methods for the estimation of vapor pressures and oxygen solubilities of fluorochemicals for possible application in artificial blood formulations (1978) J Fluorine Chemistry, 12, pp. 221-236Pantini, G., Moretti, L., Il Fomblin, H.C., Tecnologie chemiche (1988) Ano, 8, pp. 44-48. , 3, Marz

International Lung Cancer Consortium: Pooled Analysis of Sequence Variants in DNA Repair and Cell Cycle Pathways

10.1158/1055-9965.EPI-08-0411Cancer Epidemiology Biomarkers and Prevention17113081-3089CEBP

Квитанция по принятию объявление в газету "Вечернее Тбилиси"

Русудан Багратион-Мухранская - дочка Нико Бур