The Data Processing Pipeline for the Herschel-HIFI Instrument

The HIFI data processing pipeline was developed to systematically process diagnostic, calibration and astronomical observations taken with the HIFI science instrumentas part of the Herschel mission. The HIFI pipeline processed data from all HIFI observing modes within the Herschel automated processing environment, as well as, within an interactive environment. A common software framework was developed to best support the use cases required by the instrument teams and by the general astronomers. The HIFI pipeline was built on top of that and was designed with a high degree of modularity. This modular design provided the necessary flexibility and extensibility to deal with the complexity of batch-processing eighteen different observing modes, to support the astronomers in the interactive analysis and to cope with adjustments necessary to improve the pipeline and the quality of the end-products. This approach to the software development and data processing effort was arrived at by coalescing the lessons learned from similar research based projects with the understanding that a degree of foresight was required given the overall length of the project. In this article, both the successes and challenges of the HIFI software development process are presented. To support future similar projects and retain experience gained lessons learned are extracted.Comment: 18 pages, 5 figure

Computerized analytical technique for design and analysis of a Sabatier reactor subsystem Final engineering report

Mathematical model for computerized evaluation of Sabatier reaction kinetics in oxygen recovery from carbon dioxid

Freezing point of seawater

Accurate values of the freezing point of seawater are necessary for considering thermal processes at high latitudes and for relating the ice-water equilibrium to the thermodynamics of water in seawater at low temperature. Measurements of the freezing point of seawater at various salinities were made using three independent techniques. The results obtained by a super-cooling method were not reliable, whereas values based on a flow and an equilibration technique were indistinguishable...

Primary cutaneous anaplastic large cell lymphoma shows a distinct miRNA expression profile and reveals differences from tumor-stage mycosis fungoides

Copyright @ 2012 John Wiley & SonsThe miRNA expression profiles of skin biopsies from 14 primary cutaneous anaplastic large cell lymphoma (C-ALCL) patients were analysed with miRNA microarrays using the same control group of 12 benign inflammatory dermatoses (BID) as previously used to study the miRNA expression profile of tumor-stage mycosis fungoides (MF). We identified 13 differentially expressed miRNAs between C-ALCL and BID. The up-regulation of miR-155, miR-27b, miR-30c and miR-29b in C-ALCL was validated by miRNA-Q-PCR on independent study groups. Additionally, the miRNA expression profiles of C-ALCL were compared with those of tumor-stage MF. Although miRNA microarray analysis did not identify statistically significant differentially expressed miRNAs, miRNA-Q-PCR demonstrated statistically significantly differential expression of miR-155, miR-27b, miR-93, miR-29b and miR-92a between tumor-stage MF and C-ALCL. This study, the first describing the miRNA expression profile of C-ALCL, reveals differences with tumor-stage MF, suggesting a different contribution to the pathogenesis of these lymphomas.This work was funded by grants from Netherlands Organization for Scientific Research (NWO) (MHV) and the Fondation Rene´ Touraine (MvK), and grants from the Leukaemia and Lymphoma Research (EB) and the Julian Starmer-Smith Memorial Fund (CHL)

Demythologizing war journalism: Motivation and role perception of Dutch war journalists

Although, in recent years, considerable research has been done on the hazardous experiences of Anglo-Saxon war journalists, Dutch war journalists have never been the focus of academic attention. The authors thought the experiences of the Dutch might put war journalism in a new light and so they conducted a series of in-depth interviews with 12 Dutch war journalists. In this article, they address two main research questions: what are war journalists’ motives for practising this dangerous occupation and how do they perceive their professional role? The authors compared their findings to previous research on Anglo-Saxon war journalists and on Dutch journalism students and journalists. The most striking conclusion is that, compared to their Anglo-Saxon colleagues, Dutch war journalists are reluctant to present their motivation and work in moral dimensions too eagerly. Instead, all the interviewees frankly acknowledge that they are excited by the experience of war or at least seeking adventure. They equally admit to having chosen the profession partly because of career opportunities. However, this rational attitude of Dutch war journalists does not deter them from moral objectives

Experimental Investigation of Base Pressure on Blunt-Trailing-Edge Wings at Supersonic Velocities

Measurements of base pressure are presented for 29 blunt-trailing-edge wings having an aspect ratio of 3.0 and various airfoil profiles. The different profiles comprised thickness ratios between 0.05 and 0.10, boattail angles between -2.9 degrees and 20 degrees, and ratios of trailing-edge thickness to airfoil thickness between 0.2 and 1.0. The tests were conducted at Mach numbers of 1.25, 1.5, 2.0, and 3.1. For each Mach number, the Reynolds number and angle of attack were varied. The lowest Reynolds number investigated was 0.2 x 10(6) and the highest was 3.5 x 10(6). Measurements on each wing were obtained separately with turbulent flow and laminar flow in the boundary layer. Span-wise surveys of the base pressure were conducted on several wings. The results with turbulent boundary-layer flow showed only small effects on base pressure of variations in Reynolds number, airfoil profile shape, boattail angle, and angle of attack. The principal variable affecting the base pressure for turbulent flow was the Mach number