Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics

Osteosarcoma (OSA) is a rare cancer in people. However OSA incidence rates in dogs are 27 times higher than in people. Prognosis in both species is poor, with five year osteosarcoma survival rates in people not having improved in decades. For dogs, one year survival rates are only around ~45%. Improved and novel treatment regimens are urgently required to improve survival in both humans and dogs with OSA. Utilising information from genetic studies could assist in this in both species, with the higher incidence rates in dogs contributing to the dog population being a good model of human disease. This review compares the clinical characteristics, gross morphology and histopathology, aetiology, epidemiology, and genetics of canine and human osteosarcoma. Finally, the current position of canine osteosarcoma genetic research is discussed and areas for additional work within the canine population are identified

SOSORT consensus paper: school screening for scoliosis. Where are we today?

This report is the SOSORT Consensus Paper on School Screening for Scoliosis discussed at the 4th International Conference on Conservative Management of Spinal Deformities, presented by SOSORT, on May 2007. The objectives were numerous, 1) the inclusion of the existing information on the issue, 2) the analysis and discussion of the responses by the meeting attendees to the twenty six questions of the questionnaire, 3) the impact of screening on frequency of surgical treatment and of its discontinuation, 4) the reasons why these programs must be continued, 5) the evolving aim of School Screening for Scoliosis and 6) recommendations for improvement of the procedure

Fathers’ Commute to Work and Children’s Social and Emotional Well-Being in Germany

Using the German Socio-Economic Panel study, we addressed the main question: Is fathers’ commute to work associated with increases in child social and emotional well-being as measured in Strengths and Difficulties Questionnaires? If so, would this association be mediated by reduced time spent with children or moderated by change in family income due to commuting? The findings show that fathers’ daily commute to work was associated with more peer relationship problems, and it also appeared to be linked to more emotional symptoms and greater hyperactivity in children. Fathers’ weekly commute was also linked to child emotional problems. The likelihood of having peer relationship problems in children increased with the distance of fathers’ daily commute to work. This is one of only two studies on this important topic and much further research is warranted