269 research outputs found

    Türkiye’deki tromb duvar sistemine ait sayısal ısı akısı analizi

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    Trombe wall is an inexpensive passive heating design method used for storing and utilizing solar energy to increase indoor temperature without relying on any mechanical system that requires additional energy. Most recent studies concerning solar wall configuration and energy efficiency have been conducted by using computational fluid dynamics. One reason for this is because semi-transparent and opaque boundaries are provided in simulating wall and glazing surfaces around the fluid domain and solar heat flux energy are allowed in through semi-transparent boundaries. However, finite element method programs employ solid and shell elements as opaque walls that transmit the energy into the domain. In this study, numerical heat flux analysis of a Trombe wall system, which was built for a previous experimental study, has been performed and numerical and experimental analysis results have been verified. According to the simulation studies, heat transfer analysis results are obtained in a good agreement with real time measurements when additional solar load calculated due to transmissivity are defined at the surfaces which are expected to be sun exposed. Besides, numerically verified model of the Trombe wall system was used in evaluating energy saving potential of residential buildings for three cities with different climate regions in Turkey.Tromb duvar, güneş enerjisinin depolanarak iç ortam sıcaklığının ilave enerji tüketimi gerektiren herhangi bir mekanik sisteme bağımlı kalmaksızın arttırılması için kullanılan pahalı olmayan bir pasif ısıtma sistemidir. Son zamanlarda ısı duvarının konfigürasyon ve enerji verimliliğine yönelik yapılan çalışmaların çoğu hesaplamalı akışkanlar dinamiği yardımıyla gerçekleştirilmiştir. Bunun sebeplerinden bir tanesi, bu programlarda cam ve akışkan alan çevresindeki yüzey sınır koşullarının temsil edildiği yarı geçirgen ve geçirimsiz duvarların kullanıcıya sağlanması ve enerjinin sadece yarı geçirgen duvarlar içerisinden geçebilmesine izin verilmesidir. Ancak, sonlu elemanlar metodu programlarında geçirimsiz duvar özelliklerine karşılık gelen ve enerjiyi ısı akısı şeklinde aktaran katı ve kabuk elemanlar kullanılabilmektedir. Bu çalışmada, daha önce deneysel bir çalışma kapsamında inşa edilmiş Tromb duvarı sistemine ait sayısal ısı akısı analizi gerçekleştirilmiş ve sayısal analiz deneysel analiz sonuçları ile doğrulanmıştır. Simülasyon çalışmalarına göre, güneş ışığı alması beklenen yüzeylere geçirgenlik katsayısına bağlı olarak hesaplanacak ilave güneş enerjisi tanımlanması halinde elde edilen sonuçların deneysel çalışmalarla örtüştüğü görülmüştür. Bununla birlikte, sayısal olarak doğrulanmış Tromb duvar modelinin kullanılarak Türkiye’deki üç farklı iklim bölgesine ait konut yapılarındaki enerji tasarruf potansiyelinin değerlendirilmesine yönelik bir çalışma yapılmıştır

    Mutational Spectrum of the MEFV Gene in AA Amyloidosis Associated With Familial Mediterranean Fever

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    WOS: 000382833300002PubMed ID: 27225717Introduction. Familial Mediterranean fever (FMF) is a recessively inherited disease which is characterized by recurrent episodic fever, abdominal pain, and polyserositis. It is caused by mutations in the MEFV gene, encoding the pyrin protein. The most important complication of FMF is secondary (AA) amyloidosis that leads to kidney failure. This study aimed to identify the frequency and distribution of MEFV mutations in Turkish patients with FMF-associated AA amyloidosis. Materials and Methods. A total of 57 patients with FMF-associated AA amyloidosis and 60 healthy controls were included in this study. We analyzed the MEFV gene for E148Q, M694V, M680I, and V726A mutations and R202Q variant by polymerase chain reaction and restriction fragment length polymorphism methods. Results. The male-female ratio was 0.72. The mean age of the patients was 29.8 +/- 12.8 years. Among the patients, the rate of the MEFV mutations was found to be 77.2%. The most frequently observed genotype was homozygous M694V mutation, which was present in 17 patients (29.8%, P <.001), followed by compound heterozygous M680I/ M694V (14.3%, P =.01). The R202Q allele frequencies were significantly different between patients and control group (P =.02; odds ratio, 0.53; 95% confidence interval, 0.30 to 0.94). Conclusions. In this study, mutation analysis of MEFV gene confirmed that the most frequent mutation was homozygous M694V genotype. R202Q may be important in patients with FMF-associated AA amyloidosis. Thus, it is suggested that investigation of R202Q should be considered as a genetic test for Turkish FMF patients

    The Analysis of Patients Operated for Frontal Sinus Osteomas

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    Objective:Paranasal sinus osteomas are benign tumors that are smooth-walled, slow-growing, and induced by bone tissue. Although their most common localization is the frontal sinus, some osteomas are seen in the ethmoid, maxillary, and sphenoid sinuses. Frontal sinus osteomas are often asymptomatic; however, when they become symptomatic, headache is the most common complaint. In this study, we aimed to analyze the postoperative results of patients who were diagnosed with frontal sinus osteoma and were operated with appropriate surgical techniques.Methods:We retrospectively evaluated 14 patients who were diagnosed with frontal sinus osteoma and were operated in our department between March 2009 and July 2014. The following parameters were analyzed: patients’ age and gender, complaints at the time of admission to our clinic, pathological findings from physically examination, tumor features observed in preoperative paranasal sinus computed tomography (size and localization), surgical methods applied, intra- and postoperative complications, and recurrence rates. All patients preoperatively provided informed consent.Results:Of the 14 patients, 7 were males and 7 were females, with a mean age of 40.57 years. A total of 11 (79%) osteomas were located within the frontal sinus and 3 (21%) within the frontal recess. External surgical approach was performed to 11 patients, endoscopic approach was performed to 2 patients and external and endoscopic approach was performed to 1 patient together.Conclusion:Although the preferred surgical method in frontal sinus osteoma depends depended on size and localization of tumors, experience of surgeon is also important. Although the external surgical approach is appropriate for large and laterally localized osteomas, the endoscopic approach is appropriate for small and inferomedially localized osteomas. In both surgical approaches the site of origin should be drilled

    Sick euthyroid syndrome is associated with poor prognosis in patients with ST segment elevation myocardial infarction undergoing primary percutaneous intervention

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    Background: Concomitant thyroid and heart disease are frequently encountered in clinical practice. There are many studies evaluating thyroid function in acute and critical conditions. Information on thyroid dysfunction in ST-segment elevation myocardial infarction (STEMI) is limited; its correlation with short and long-term outcome is not fully known.Methods: Four hundred and fifty seven patients diagnosed with STEMI in our emergency department were included in the study. Patients were divided into two groups: patients with normal thyroid function (euthyroid) and patients with thyroid dysfunction. STEMI was diagnosed with 12 derivation surface electrocardiogram. Thyroid hormone levels (TSH, free T3 and free T4) were measured. Patients with other acute coronary syndromes and endocrine pathologies except diabetes mellitus were excluded. Two patient groups were compared in terms of in-hospital and long-term outcome.Results: Out of 457, 72 (15%) patients with thyroid dysfunction were detected. The other patients were euthyroid and constituted the control group. In-hospital cardiogenic shock (15% vs. 3% in the control group; p &lt; 0.01) and death (7% vs. 1% in the control group; p &lt; 0.01) were more frequently observed in the thyroid dysfunction group. In the subgroup analysis, it was observed that patients with sick euthyroid syndrome have the poorest outcome. Other markers for poor outcome were anemia and renal failure.Conclusions: Thyroid dysfunction, particularly sick euthyroid syndrome, was found to be related to in-hospital and long term mortality in patients with STEMI undergoing primary percutaneous intervention

    Estimation of Reference Evapotranspiration Using Support Vector Machines: a Case Study of Adana, Turkey.

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    Evapotranspiration is an important parameter in hydrological and meteorological studies. Evapotranspiration forecasting plays an important role in irrigation management and hydraulic designs, especially during dry periods. In this study, average temperature (T), relative humidity (RH), wind speed (U), solar radiation (SR) parameters were used to estimate the daily evapotranspiration amount. Daily evapotranspiration estimation (ET0) was made according to the Penman-Monteith method recommended by FAO (Food and Agriculture Organization) as a standard method. The Penman-Monteith method was considered as the reference equation. Support Vector Machines (SVM) methods with four different input combinations were used to estimate the daily evapotranspiration of Adana province. SVM models were compared with each other and the reference equations’ results. According to the results obtained from SVM models, SVM3 model giave slightly better results according to the higher determination coefficient and lowest error data

    Lingual Osseous Choristoma

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    An osseous choristoma is a rare benign lesion consisting of normal bone tissue; it is seen in abnormal locations. It is most often seen in the posterior 1/3 of the tongue in the head. Its etiopatogenesis is controversial, and till date, less than 100 cases have been reported in the literature. Although a lingual osseous choristoma is asymptomatic, in some patients, symptoms such as swelling sensation in the throat, globus pharyngeus, dysphagia, retching, nausea, and sore throat have been reported. In this article, a 41-yearold female patient admitted to our clinic with throat pain and globus pharyngeus who underwent an excision from the region of radix lingua and the result of histopathological examination was reported as "osseous choristoma" was presented and related literature is reviewed

    Numerical Modeling of Submerged Vane Flow

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    Scours in rivers occur due to high flow velocities. In order to reduce scour, flow velocities need to be reduced. Submerged vane structures are effective in both reducing the flow rate and directing the flow. In this study, numerical modeling was made with submerged vane structures. Models of the measured flow velocities in the channel, where submerged vane experiments were performed before, were compared with the results of the submerged vane experiment by using the 3-dimensional computational fluid dynamics (CFD) method. In the present CFD model, continuity and momentum, turbulence model equations are applied. For the turbulence viscosity, k-ε turbulence model is used. The results of the present model are compared with the previous experimental work

    Comparison of adjacent segment degeneration in patients using cervical cage and disc prosthesis in anterior cervical surgery

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    Aim: To examine the prevalence of adjacent segment degeneration associated with the use of cages and disc prostheses in patients who underwent cervical disc surgery via an anterior cervical approach. Methods: We retrospectively reviewed the medical records of 60 patients who underwent cervical disc surgery via an anterior cervical approach at our clinic between 2018 and 2023. The patients were divided into two groups based on the type of implant used: those with a cervical cage (Group 1) and those with a cervical disc prosthesis (Group 2). Patients' demographic and clinical details, including age, gender, smoking habits, follow-up durations, and any additional comorbid diseases, were recorded. Radiological evaluations focused on degeneration rates in the segments adjacent to where either the cage or disc prosthesis was implanted. Results: In the study comparing two groups, participants' average ages were 48.9 in Group 1 and 48.1 in Group 2 (p=0.720). Group 1 had a higher proportion of smokers (p=0.052) and more discopathy (p=0.196). In terms of disc degenerations, variations existed but were not statistically significant (p=0.259). Utilizing the Pfirrmann grading, Group 1 had more Grade III degeneration (p=0.088) and a significantly higher presence of ossification or osteophytes (p=0.038). Both groups showed high rates of adjacent segment degeneration, yet Group 1 had notably more proximal degeneration (p=0.012). Stenosis and facet hypertrophy differences were not significant (p=0.417, p=0.071). Follow-up duration averaged around 38 months for both groups (p=0.929). Conclusions: No substantial difference in the overall incidence of adjacent segment degeneration between the two procedures. Nevertheless, further large-scale and long-term studies are essential to draw comprehensive conclusions regarding the optimal surgical intervention for cervical disc ailments

    Unraveling Molecular Fingerprints of Catalytic Sulfur Poisoning at the Nanometer Scale with Near-Field Infrared Spectroscopy

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    Fundamental understanding of catalytic deactivation phenomena such as sulfur poisoning occurring on metal/metal-oxide interfaces is essential for the development of high-performance heterogeneous catalysts with extended lifetimes. Unambiguous identification of catalytic poisoning species requires experimental methods simultaneously delivering accurate information regarding adsorption sites and adsorption geometries of adsorbates with nanometer-scale spatial resolution, as well as their detailed chemical structure and surface functional groups. However, to date, it has not been possible to study catalytic sulfur poisoning of metal/metal-oxide interfaces at the nanometer scale without sacrificing chemical definition. Here, we demonstrate that near-field nano-infrared spectroscopy can effectively identify the chemical nature, adsorption sites, and adsorption geometries of sulfur-based catalytic poisons on a Pd(nanodisk)/Al2O3 (thin-film) planar model catalyst surface at the nanometer scale. The current results reveal striking variations in the nature of sulfate species from one nanoparticle to another, vast alterations of sulfur poisoning on a single Pd nanoparticle as well as at the assortment of sulfate species at the active metal-metal-oxide support interfacial sites. These findings provide critical molecular-level insights crucial for the development of long-lifetime precious metal catalysts resistant toward deactivation by sulfur

    Epidemiology of pemphigus in Turkey: One-year prospective study of 220 cases

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    Pemphigus is a group of rare and life-threatening autoimmune blistering diseases of the skin and mucous membranes. Although they occur worldwide, their incidence shows wide geographical variation, and prospective data on the epidemiology of pemphigus are very limited. Objective of this work is to evaluate the incidence and epidemiological and clinical features of patients with pemphigus in Turkey. All patients newly diagnosed with pemphigus between June 2013 and June 2014 were prospectively enrolled in 33 dermatology departments in 20 different provinces from all seven regions of Turkey. Disease parameters including demography and clinical findings were recorded. A total of 220 patients were diagnosed with pemphigus during the 1-year period, with an annual incidence of 4.7 per million people in Turkey. Patients were predominantly women, with a male to female ratio of 1:1.41. The mean age at onset was 48.9 years. Pemphigus vulgaris (PV) was the commonest clinical subtype (n=192; 87.3%), followed by pemphigus foliaceus (n=21; 9.6%). The most common clinical subtype of PV was the mucocutaneous type (n=83; 43.2%). The mean Pemphigus Disease Area Index was 28.14±22.21 (mean ± Standard Deviation).  The incidence rate of pemphigus in Turkey is similar to the countries of South-East Europe, higher than those reported for the Central and Northern European countries and lower than the countries around the Mediterranean Sea and Iran. Pemphigus is more frequent in middle-aged people and is more common in women. The most frequent subtype was PV, with a 9-fold higher incidence than pemphigus foliaceus.   </p
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