18 research outputs found

    Effect of different light intensities on prolactin and cortisol plasma concentration in farming African catfish (Clarias gariepinus) in RAS with low-water exchange

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    In the Bulgarian aquaculture sector, focusing research efforts on the technical specifications of the cultivation of African catfish (Clarias gariepinus) is important due to the need for more information. We aimed to assess the impact of light intensities on prolactin and cortisol levels as stress markers in African catfish. Fish were acclimated over an appropriate period to the short photoperiod (16D and 8L) and then distributed randomly to three groups, each separated by sex. Fish exposed to different light intensities (63, 51, and 40 lux, respectively) were followed for 45 days by lux meter. Blood samples were collected from the caudal vein using a 2 ml K2EDTA-coated syringe. A laser fluorescence reader assayed plasma prolactin and cortisol. The pituitary was removed from anesthetized fish and fixed for histological examinations. The results of our study suggest that increasing light intensity increases prolactin and cortisol levels in African catfish

    Endoplasmic reticulum stress in case of hypothyroidism: focus on hippocampus and amygdala

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    41st FEBS Congress on Molecular and Systems Biology for a Better Life -- SEP 03-08, 2016 -- Kusadasi, TURKEYWOS: 000383616900209…FEB

    Investor sentiment and stock returns: Evidence from turkey

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    This paper investigates the relation between investor sentiment and stock returns on the Istanbul Stock Exchange, employing vector autoregressive (VAR) analysis and Granger causality tests. The sample period extends from July 1997 to June 2005. In the VAR models, stock portfolio returns and investor sentiment proxies are used as endogenous variables. Two dummy variables accounting for natural and economic crises are used as exogenous variables. The analysis results suggest that, excepting shares of equity issues in aggregate issues, stock portfolio returns seem to affect all investor sentiment proxies. copyright © 2009 M.E. Sharpe, Inc

    Effects of Exercise on ADAMTS-4 and ADAMTS-5 Levels in Sport Horses

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    WOS: 000408842000350…Cukurova University Scientific Research Projects (BAP)Cukurova University [9288]This study was supported by Cukurova University Scientific Research Projects (BAP), Project No: 928

    Effects of The Dietary Supplementation of Layer Diets with Natural and Synthetic Antioxidant Additives on Yolk Lipid Peroxidation and Fatty Acid Composition of Eggs Stored at Different Temperatures and Duration

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    WOS: 000498802700010In this study, the effects of the supplementation of natural and synthetic antioxiciant additives in layer diets on egg weight loss, yolk lipid peroxidation ([BARS values) and fatty acid composition of eggs stored at different temperatures and duration were evaluated. In total, 112 48- weeks-old Bovans White layers were randomly allotted to four dietary treatments with four replicates of seven birds each. The treatments consisted of a control diet, containing no additives, and diets with the inclusion of 200 mg synthetic vitamin E/kg, 1000 mg thyme extract/kg and 1000 mg rosemary extract/kg. Dietary treatments did not influence (p>0.05) relative weight loss of eggs stored for 14, 28, and 56 days, except for those from rosemary-fed hens stored at room temperature on d 42, which were significantly lighter than the eggs from vitamin E- and thyme-fed hens (p0.05) of dietary treatment on yolk TBARS values were detected in refrigerated eggs. The inclusion of the synthetic and both natural antioxidants in layer diets significantly reduced stearic acid (C18: 0) level in the egg yolk. In addition, only natural antioxidants significantly increased yolk levels of palmitoleic acid (C16: 1) and vaccenic acid (C18: 1n7). The results of the present study showed that adequate storage temperature was more effective in improving egg shelf life than feeding layers synthetic or natural antioxidant additives. However, the positive effects of the evaluated natural antioxidants on yolk fatty acid composition suggest their supplementation to layer diets may provide health benefits to the consumer

    Endoplasmic reticulum stress participates in the pathophysiology of mercury-caused acute kidney injury

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    PubMedID: 31736398Acute exposure to mercury chloride (HgCl2) causes acute kidney injury (AKI). Some metals interfere with protein folding, leading to endoplasmic reticulum stress (ERS), and the activation of cell death mechanisms, but in the case of mercury, there is no knowledge about whether the ERS mediates tubular damage. This study aimed to determinate if HgCl2 causes an AKI course with temporary activation of ERS and if this mechanism is involved in kidney cell death. Male mice were intoxicated with 5 mg/kg HgCl2 and sacrificed after 24, 48, 72, and 96 h of mercury administration. The kidneys of euthanized mice were used to assess the renal function, oxidative stress, redox environment, antioxidant enzymatic system, cell death, and reticulum stress markers (PERK, ATF-6, and IRE1? pathways). The results indicate temporary-dependent renal dysfunction, oxidative stress, and an increase of glutathione-dependent enzymes involved in the bioaccumulation process of mercury, as well as the enhancement of caspase 3 activity along with IRE1a, GADD-153, and caspase 12 expressions. Mercury activates the PERK/eIF2? branch during the first 48 h. Meanwhile, the activation of PERK/ATF-4 branch allowed for ATF-4, ATF-6, and IRE1? pathways to enhance GADD-153. It led to the activation of caspases 12 and 3, which mediated the deaths of the tubular and glomerular cells. This study revealed temporary-dependent ERS present during AKI caused by HgCl2, as well as how it plays a pivotal role in kidney cell damage. © 2019, © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.Secretaría de Investigación y Posgrado, Instituto Politécnico Nacional Consejo Nacional de Ciencia y TecnologíaEdgar Cano-Europa thanks COTEBAL-IPN for the support given this year for the realization of this project. The authors thank INSTITUTO POLITÉCNICO NACIONAL, SECRETARÍA DE INVESTIGACIÓN Y POSGRADO-IPN, and CONACyT for financial support. The researchers are fellows of EDI, COFAA, and SNI
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