Associations Between Age and Resting State Connectivity Are Partially Dependent Upon Cardiovascular Fitness

Previous research suggests a marked impact of aging on structural and functional connectivity within the frontoparietal control network (FPCN) and default mode network (DMN). As aging is also associated with reductions in cardiovascular fitness, age-related network connectivity differences reported by past studies could be partially due to age-related declines in fitness. Here, we use data collected as part of a 16-week exercise intervention to explore relationships between fitness and functional connectivity. Young and older adults completed baseline assessments including cardiovascular fitness, health and functioning measures, and an fMRI session. Scan data were acquired on a Siemens 3T MRI scanner with a 32-channel head coil. Results from regression analyses indicated that average connectivity did not differ between young and older adults. However, individual ROI-to-ROI connectivity analyses indicated weaker functional correlations for older adults between specific regions in the FPCN and DMN and, critically, many of these differences were attenuated when fitness was accounted for. Taken together, findings suggest that fitness exerts regional rather than global effects on network connectivity. Copyright © 2022 Gust, Moe, Seals, Banich, Andrews-Hanna, Hutchison and Bryan.Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

THE POLITICS OF LEGISLATIVE OVERSIGHT: MONITORING EDUCATIONAL REFORM IN SIX STATES

Legislative oversight traditionally has been viewed as a rational tool for achieving democratic accountability. Legislators conduct oversight to ensure consistency between implementation and official policy directives. The major theme of this paper is t h a t oversight is best understood as an integral part of legislative-administrative politics. By examining how six states monitored recent educational reforms, the author finds that legislators conducted oversight in ways that minimized time commitments and maximized political benefits. Copyright 1989 by The Policy Studies Organization.

Comparison of flock characteristics, journey duration and pathology between flocks with a normal and a high percentage of broilers ‘dead-on-arrival’ at abattoirs

acceptedVersio

Impaired balance in developmental dyslexia? A meta-analysis of the contending evidence

Background: Developmental dyslexia is typically defined by deficits in phonological skills, but it is also associated with anomalous performance on measures of balance. Although balance assessments are included in several screening batteries for dyslexia, the association between impairments in literacy and deficits in postural stability could be due to the high co-occurrence of dyslexia with other developmental disorders in which impairments of motor behaviour are also prevalent. Methods: We identified 17 published studies that compared balance function between dyslexia and control samples and obtained effect-sizes for each. Contrast and association analyses were used to quantify the influence of hypothesised moderator variables on differences in effects across studies. Results: The mean effect-size of the balance deficit in dyslexia was .64 (95% CI = .44-.78) with heterogeneous findings across the population of studies. Probable co-occurrence of other developmental disorders and variability in intelligence scores in the dyslexia samples were the strongest moderator variables of effect-size. Conclusions: Balance deficits are associated with dyslexia, but these effects are apparently more strongly related to third variables other than to reading ability. Deficits of balance may indicate increased risk of developmental disorder, but are unlikely to be uniquely associated with dyslexia