19,793 research outputs found
Nonlinear ER effects in an ac applied field
The electric field used in most electrorheological (ER) experiments is
usually quite high, and nonlinear ER effects have been theoretically predicted
and experimentally measured recently. A direct method of measuring the
nonlinear ER effects is to examine the frequency dependence of the same
effects. For a sinusoidal applied field, we calculate the ac response which
generally includes higher harmonics. In is work, we develop a multiple image
formula, and calculate the total dipole moments of a pair of dielectric
spheres, embedded in a nonlinear host. The higher harmonics due to the
nonlinearity are calculated systematically.Comment: Presented at Conference on Computational Physics (CCP2000), held at
Gold Coast, Australia from 3-8, December 200
Nonlinear ac response of anisotropic composites
When a suspension consisting of dielectric particles having nonlinear
characteristics is subjected to a sinusoidal (ac) field, the electrical
response will in general consist of ac fields at frequencies of the
higher-order harmonics. These ac responses will also be anisotropic. In this
work, a self-consistent formalism has been employed to compute the induced
dipole moment for suspensions in which the suspended particles have nonlinear
characteristics, in an attempt to investigate the anisotropy in the ac
response. The results showed that the harmonics of the induced dipole moment
and the local electric field are both increased as the anisotropy increases for
the longitudinal field case, while the harmonics are decreased as the
anisotropy increases for the transverse field case. These results are
qualitatively understood with the spectral representation. Thus, by measuring
the ac responses both parallel and perpendicular to the uniaxial anisotropic
axis of the field-induced structures, it is possible to perform a real-time
monitoring of the field-induced aggregation process.Comment: 14 pages and 4 eps figure
Novel method for refinement of retained austenite in micro/nano-structured bainitic steels
A comparative study was conducted to assess the effects of two different heat treatments on the amount and morphology of the retained austenite in a micro/nano-structured bainitic steel. The heat treatments used in this work were two-stage bainitic transformation and bainitic-partitioning transformation. Both methods resulted in the generation of a multi-phase microstructure containing nanoscale bainitic ferrite, and/or fresh martensitic phases and much finer retained austenite. Both heat treatments were verified to be effective in refining the retained austenite in micro/nano-structured bainite and increasing the hardness. However, the bainitic transformation followed by partitioning cycle was proved to be a more viable approach than the two-stage bainitic transformation due to much shorter processing time, i.e. ∼2 h compared to ∼4 day, respectively
A Particle Element Approach for Modelling the 3D Printing Process of Fibre Reinforced Polymer Composites
This paper presents a new numerical approach for modelling the 3D printing process of fibre reinforced polymer composites by fused deposition modelling (FDM). The approach is based on the coupling between two particle methods, namely smoothed particle hydrodynamics (SPH) and discrete element method (DEM). The coupled SPH-DEM model has distinctive advantages in dealing with the free surface flow, large deformation of fibres, and/or fibre-fibre interaction that are involved in the FDM process. A numerical feasibility study is carried out to demonstrate its capability for both short and continuous fibre reinforced polymer composites, with promising results achieved for the rheological flow and fibre orientation and deformation. View Full-Tex
Theory of the "honeycomb chain-channel" reconstruction of Si(111)3x1
First-principles electronic-structure methods are used to study a structural
model for Ag/Si(111)3x1 recently proposed on the basis of transmission electron
diffraction data. The fully relaxed geometry for this model is far more
energetically favorable than any previously proposed, partly due to the unusual
formation of a Si double bond in the surface layer. The calculated electronic
properties of this model are in complete agreement with data from
angle-resolved photoemission and scanning tunneling microscopy.Comment: 4 pages, 4 figures, submitted to Phys. Rev. Lett (the ugly postscript
error on page 4 has now been repaired
Transcriptome and metabolome reveal redirection of flavonoids in a white testa peanut mutant
Background: Coat color determines both appearance and nutrient quality of peanut. White seed coat in peanut
can enhance the processing efficiency and quality of peanut oil. An integrative analysis of transcriptomes,
metabolomes and histocytology was performed on wsc mutant and its wild type to investigate the regulatory
mechanisms underlying color pigmentation.
Result: Metabolomes revealed flavonoids were redirected in wsc, while multi-omics analyses of wsc mutant seeds
and testae uncovered WSC influenced the flavonoids biosynthesis in testa as well as suberin formation, glycolysis,
the TCA cycle and amino acid metabolism. The mutation also enhanced plant hormones synthesis and signaling.
Further, co-expression analysis showed that FLS genes co-expressed with MBW complex member genes.
Combining tissue expression patterns, genetic analyses, and the annotation of common DEGs for these three stages
revealed that three testa specific expressed candidate genes, Araip.M7RY3, Aradu.R8PMF and Araip.MHR6K were likely
responsible for the white testa phenotype. WSC might be regulated expression competition between FLS and DFR
by controlling hormone synthesis and signaling as well as the MBW complex.
Conclusions: The results of this study therefore provide both candidate genes and novel approaches that can be
applied to improve peanut with desirable seed coat color and flavonoid quality
Spin-orbit tuned metal-insulator transitions in single-crystal Sr2Ir1-xRhxO4 (0\leqx\leq1)
Sr2IrO4 is a magnetic insulator driven by spin-orbit interaction (SOI)
whereas the isoelectronic and isostructural Sr2RhO4 is a paramagnetic metal.
The contrasting ground states have been shown to result from the critical role
of the strong SOI in the iridate. Our investigation of structural, transport,
magnetic and thermal properties reveals that substituting 4d Rh4+ (4d5) ions
for 5d Ir4+(5d5) ions in Sr2IrO4 directly reduces the SOI and rebalances the
competing energies so profoundly that it generates a rich phase diagram for
Sr2Ir1-xRhxO4 featuring two major effects: (1) Light Rh doping (0\leqx\leq0.16)
prompts a simultaneous and precipitous drop in both the electrical resistivity
and the magnetic ordering temperature TC, which is suppressed to zero at x =
0.16 from 240 K at x=0. (2) However, with heavier Rh doping (0.24< x<0.85
(\pm0.05)) disorder scattering leads to localized states and a return to an
insulating state with spin frustration and exotic magnetic behavior that only
disappears near x=1. The intricacy of Sr2Ir1-xRhxO4 is further highlighted by
comparison with Sr2Ir1-xRuxO4 where Ru4+(4d4) drives a direct crossover from
the insulating to metallic states.Comment: 5 figure
L-functions of Symmetric Products of the Kloosterman Sheaf over Z
The classical -variable Kloosterman sums over the finite field
give rise to a lisse -sheaf on , which we call the Kloosterman
sheaf. Let be the
-function of the -fold symmetric product of . We
construct an explicit virtual scheme of finite type over such that the -Euler factor of the zeta function of coincides with
. We also prove
similar results for and .Comment: 16 page
Fumaric acid ester–induced renal Fanconi syndrome: evidence of mitochondrial toxicity
Background:
Fumaric acid esters (FAEs) are used to treat chronic plaque psoriasis. Fumarate is a crucial component of the Krebs cycle and mitochondrial function. Proximal tubule cells have high energy demands and rely on aerobic respiration. Proximal tubular dysfunction can cause renal Fanconi syndrome and acute kidney injury. We sought to better understand the mechanism for this in the context of FAE therapy.
Methods:
We describe a case series of 10 patients with FAE-associated Fanconi syndrome. Patients were diagnosed and managed at a tertiary renal tubular disorder clinic, with examination of serum and urine biochemistry. Five patients had a renal biopsy with examination of the specimens by electron microscopy.
Results:
The median age was 36.5 years [interquartile range (IQR) 32.25–54.25]. The median dose of FAE was 720 mg/day (IQR 390–720). There was low molecular weight proteinuria: the median urinary retinol-binding protein (RBP) at presentation was 8385 μg/mL (IQR 2793–14 600) and the RBP:creatinine ratio was 710 (IQR 390–2415). All patients had hyperphosphaturia [median fractional excretion of phosphate 24.2% (IQR 20.8–26.9), normal range <20%] as well as relative hypophosphataemia, with a median serum phosphate concentration of 0.93 mmol/L (IQR 0.83–0.97). Renal histology showed proximal tubular damage and abnormal mitochondrial morphology. Two patients had a favourable biochemical response to treatment with probenecid.
Conclusions:
We document for the first time that FAE-associated renal Fanconi syndrome is associated with mitochondrial damage visible on electron microscopy. This effect may be ameliorated by antagonism of the organic anion transporter with probenecid
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