Effects of dietary vitamin D3 levels on survival, mineralization, and skeletal development of gilthead seabream (Sparus aurata) larvae

Vitamin D is an essential fat soluble micronutrient that helps in growth, bone development, calcium homeostasis and other metabolic process. The study on effect of vitamin D3 in marine fish larvae were very scarce irrespective of species. The present study determines the impacts of dietary vitamin D3 on growth performance, calcium absorption, mineralization, and skeletal anomalies during the development of gilthead seabream (Sparus aurata) larvae was assessed until 47 days post hatching. Diets containing four levels of vitamin D3 (0, 25, 30, 384 μg kg−1 or 11.6, 1000, 1200, 15,360 IU kg−1) were formulated to determine the effect of vitamin D3 at deficient, excess, and optimum levels. The gilthead seabream larvae in the present study fed with this wide range of vitamin D3 presented a constant growth with all the diets but presented signs of toxicity in excess level, affecting the survival, calcium uptake, and bone biomarker mechanism in larvae, which resulted in increased skeletal anomalies and mortality. An increase of dietary vitamin D3 up to 384 μg kg−1 significantly raised the whole body vitamin D3 content, calcium, and phosphorus intake and increased the incidence of skeletal anomalies, particularly cranial anomalies. The appearance of skeletal anomalies in larvae fed 384 μg kg−1 vitamin D3 was in association with the upregulation of bmp2, alp, and oc gene expression. However, larvae fed 0, 25, 30 μg kg−1 vitamin D3 showed higher survival than the group fed 384 μg kg−1 vitamin D3. Meanwhile vitamin D3 deficient diet 0 μg kg−1 presented with lower mineralization rate and increase incidence of maxillary anomaly. Thus, the current study revealed the evidence of vitamin D3 deficiency as well as toxicity in gilthead seabream larvae during the developmental process and conclude that the recommended dietary vitamin D3 level for gilthead seabream larvae may range between 25 and 30 μg kg−1 which improves larval survival, calcium and phosphate level and vertebral mineralization with reduced incidence of skeletal anomalies in gilthead seabream larva

Dynamical mass generation of a two-component fermion in Maxwell-Chern-Simons QED_3: The lowest ladder approximation

Dynamical mass generation of a two-component fermion in $QED_3$ with a Chern-Simons term is investigated by solving the Schwinger-Dyson equation formulated in the lowest ladder approximation. Dependence of the dynamical fermion mass on a gauge-fixing parameter, a gauge coupling constant, and a topological mass is examined by approximated analytical and also numerical methods. The inclusion of the Chern-Simons term makes impossible to choose a peculiar gauge in which a wave function renormalization is absent. The numerical evaluation shows that the wave function renormalization is fairly close to 1 in the Landau gauge. It means that this gauge is still a specific gauge where the Ward-Takahashi identity is satisfied approximately. We also find that the dynamical mass is almost constant if the topological mass is larger than the coupling constant, while it decreases when the topological mass is comparable to or smaller than the coupling constant and tends to the value in $QED_3$ without the Chern-Simons term.Comment: 22 pages, 9 figures, Version to appear in Phys. Rev.

Universal de Sitter solutions at tree-level

Type IIA string theory compactified on SU(3)-structure manifolds with orientifolds allows for classical de Sitter solutions in four dimensions. In this paper we investigate these solutions from a ten-dimensional point of view. In particular, we demonstrate that there exists an attractive class of de Sitter solutions, whose geometry, fluxes and source terms can be entirely written in terms of the universal forms that are defined on all SU(3)-structure manifolds. These are the forms J and Omega, defining the SU(3)-structure itself, and the torsion classes. The existence of such universal de Sitter solutions is governed by easy-to-verify conditions on the SU(3)-structure, rendering the problem of finding dS solutions purely geometrical. We point out that the known (unstable) solution coming from the compactification on SU(2)x SU(2) is of this kind.Comment: 20 pages, 3 figures, v2: added reference

Higher-Derivative Quantum Cosmology

The quantum cosmology of a higher-derivative derivative gravity theory arising from the heterotic string effective action is reviewed. A new type of Wheeler-DeWitt equation is obtained when the dilaton is coupled to the quadratic curvature terms. Techniques for solving the Wheeler-DeWitt equation with appropriate boundary conditions shall be described, and implications for semiclassical theories of inflationary cosmology will be outlined.Comment: 11 pages TeX. A term has been removed from equation (13

Polarization and magnetization dynamics of a field-driven multiferroic structure

We consider a multiferroic chain with a linear magnetoelectric coupling induced by the electrostatic screening at the ferroelectric/ferromagnet interface. We study theoretically the dynamic ferroelectric and magnetic response to external magnetic and electric fields by utilizing an approach based on coupled Landau- Khalatnikov and finite-temperature Landau-Lifshitz-Gilbert equations. Additionally, we compare with Monte Carlo calculations. It is demonstrated that for material parameters corresponding to BaTiO3/Fe the polarization and the magnetization are controllable by external magnetic and electric fields respectively

Metastable de Sitter vacua in N=2 to N=1 truncated supergravity

We study the possibility of achieving metastable de Sitter vacua in general N=2 to N=1 truncated supergravities without vector multiplets, and compare with the situations arising in N=2 theories with only hypermultiplets and N=1 theories with only chiral multiplets. In N=2 theories based on a quaternionic manifold and a graviphoton gauging, de Sitter vacua are necessarily unstable, as a result of the peculiar properties of the geometry. In N=1 theories based on a Kahler manifold and a superpotential, de Sitter vacua can instead be metastable provided the geometry satisfies some constraint and the superpotential can be freely adjusted. In N=2 to N=1 truncations, the crucial requirement is then that the tachyon of the mother theory be projected out from the daughter theory, so that the original unstable vacuum is projected to a metastable vacuum. We study the circumstances under which this may happen and derive general constraints for metastability on the geometry and the gauging. We then study in full detail the simplest case of quaternionic manifolds of dimension four with at least one isometry, for which there exists a general parametrization, and study two types of truncations defining Kahler submanifolds of dimension two. As an application, we finally discuss the case of the universal hypermultiplet of N=2 superstrings and its truncations to the dilaton chiral multiplet of N=1 superstrings. We argue that de Sitter vacua in such theories are necessarily unstable in weakly coupled situations, while they can in principle be metastable in strongly coupled regimes.Comment: 40 pages, no figure

The Boundary Multiplet of N=4 SU(2)xU(1) Gauged Supergravity on Asymptotically-AdS_5

We consider N=4 SU(2)xU(1) gauged supergravity on asymptotically-AdS_5 backgrounds. By a near-boundary analysis we determine the boundary-dominant components of the bulk fields from their partially gauge-fixed field equations. Subdominant components are projected out in the boundary limit and we find a reduced set of boundary fields, constituting the N=2 Weyl multiplet. The residual bulk symmetries are found to act on the boundary fields as four-dimensional diffeomorphisms, N=2 supersymmetry and (super-)Weyl transformations. This shows that the on-shell N=4 supergravity multiplet yields the N=2 Weyl multiplet on the boundary with the appropriate local N=2 superconformal transformations. Building on these results we use the AdS/CFT conjecture to calculate the Weyl anomaly of the dual four-dimensional superconformal field theories in a generic bosonic N=2 conformal supergravity background.Comment: 23 pages; to appear in JHE

Accelerating Universes in String Theory via Field Redefinition

We study cosmological solutions in the effective heterotic string theory with $\alpha'$-correction terms in string frame. It is pointed out that the effective theory has an ambiguity via field redefinition and we analyze generalized effective theories due to this ambiguity. We restrict our analysis to the effective theories which give equations of motion of second order in the derivatives, just as "Galileon" field theory. This class of effective actions contains two free coupling constants. We find de Sitter solutions as well as the power-law expanding universes in our four-dimensional Einstein frame. The accelerated expanding universes are always the attractors in the present dynamical system.Comment: 22 pages, 3 figures, some additional formulae adde