Influence of Supply Chain Management on Universities Development: An Outward Glance

This study is devoted to assessing the supply chain management impact on universities promotion and efficiency in international and Russian universities' ratings on their development. The peculiarity of the study is that it considers both universities participating in the competitive recovery program and presented in international rankings, as well as those that do not participate therein. The paper analyzes the rating indicators, the development strategy and the positioning of four Russian universities: Kazan (Volga Region) Federal University (KFU), National Research University "Higher School of Economics" (HSE), M.T. Kalashnikov Izhevsk State Technical University (IzhSTU) and G.R. Derzhavin Tambov State University (TSU). The research revealed the positive effects of the promotion in the university rankings on their development, among which the following can be distinguished: the formation of a competitive environment within the university, the definition of a specific strategic goal, the attraction of more qualified personnel to the university, including from the international academic market, etc. Negative consequences were revealed too, such as: increase in the workload on teachers, and as a result, reduced attention to the organization of the educational process, higher risk of losing the quality of scientific research, as a result of increasing the number of publications, ineffective spending of the university funds

Structure and phase composition of alloyed intermetallic compound Ni₃Al after annealing and high-temperature creep

The structure and phase composition of a VKNA-25 alloy based on the Ni₃Al intermetallic compound, produced by directional solidification, and alloyed with rare-earth metals are studied in the following two states: after annealing at 1100°C and after creep at 1100°CyesBelgorod State Universit

Structure and phase composition of alloyed intermetallic compound Ni₃Al after annealing and high-temperature creep

yesThe structure and phase composition of a VKNA-25 alloy based on the Ni₃Al intermetallic compound, produced by directional solidification, and alloyed with rare-earth metals are studied in the following two states: after annealing at 1100°C and after creep at 1100°CBelgorod State Universit

Variants of RBM20 gene in pediatric patients with dilated cardiomyopathy

Aim. Description of three clinical cases of pediatric patients with dilated cardiomyopathy (DCMP) and an analysis of their genetic causes.Material and methods. Using the method of targeted sequencing, data were obtained on the presence of pathogenic variants of the RBM20 gene in three pediatric patients with DCMP.Results. Three cases of childhood DCMP development, associated with structural disorders in the RBM20 gene, are particularly described. It is known that RBM20 is involved in the splicing of mRNA of the TTN gene encoding the titin protein. A splicing disorder associated with pathogenic variants in the RBM20 gene can lead to a change in biomechanical and signaling processes in myocardial cells, causing pathological dilated remodeling and rhythm disorders.Conclusion. Variants in the RBM20 gene are associated with severe DCMP with a childhood debut. In some cases, the progression of RBM20-associated cardiomyopathies is associated with an infectious disease. Further study of the molecular mechanisms of the pathogenesis of DCMP associated with pathogenic variants in the TTN and RBM20 genes is extremely relevant for both clinical cardiology and fundamental medicine