151 research outputs found
pembrolizumab in patients with recurrent or metastatic cutaneous squamous cell carcinoma cscc the phase ii keynote 629 study
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Design Study of CANGAROO-III, Stereoscopic Imaging Atmospheric Cherenkov Telescopes for sub-TeV Gamma-ray
CANGAROO-III is an Imaging Atmospheric Cherenkov Telescope (IACT) array of
four 10 m telescopes for very high energy (sub-TeV) gamma-ray astronomy. A
design study of the CANGAROO-III telescope system was carried out using the
Monte Carlo technique in order to optimize the pixel size and the telescope
spacing. Studies were also made of observations at low elevation angles.Comment: 17pages, 13 figures, elsart, to appear in Astro. Part. Phy
CANGAROO-III Search for Gamma Rays from SN 1987A and the Surrounding Field
Optical images of SN 1987A show a triple ring structure. The inner (dust)
ring has recently increased in brightness and in the number of hot spots
suggesting that the supernova shock wave has collided with the dense
pre-existing circumstellar medium, a scenario supported by radio and X-ray
observations. Such a shocked environment is widely expected to result in the
acceleration of charged particles, and the accompanying emission of very high
energy gamma-rays. Here, we report the results of observations made in 2004 and
2006 which yield upper limits on the TeV gamma-ray flux, which are compared
with a theoretical prediction. In addition, we set upper limits on the TeV flux
for four high energy objects which are located within the same field of view of
the observation: the super-bubble 30 Dor C, the Crab-like pulsar PSR
B054069, the X-ray binary LMC X-1, and the supernova remnant N157B.Comment: 5 pages, 5 figures, Accepted for publication in Ap
Evaluation of the use of pharmacological treatment with prisoners experiencing high levels of hypersexual disorder
This paper presents an evaluation of the impact of pharmacological treatment in reducing hypersexual disorder in adult males who have been incarcerated following conviction for a sexual offence. The evaluation compares two types of pharmacological treatment, one of which is part of the current NICE guidance for treatment of hypersexuality (Antiandrogens), whilst the other type (SSRIs) is off-label use in the UK for hypersexuality. The participant pool comprised 127 adult male prisoners serving sentences for sexual offences in a UK prison. Participants had been voluntarily referred for pharmacological treatment to manage hypersexual disorder. The results demonstrated a significant reduction of hypersexual disorder pre- and post-medication and contribute to the evidence base for the use of pharmacological treatment with individuals for whom hypersexual disorder may be a salient factor in their offending. Limitations of the current research are discussed
Observation of Very High Energy Gamma Rays from HESS J1804-216 with CANGAROO-III Telescopes
We observed the unidentified TeV gamma-ray source HESS J1804-216 with the
CANGAROO-III atmospheric Cerenkov telescopes from May to July in 2006. We
detected very high energy gamma rays above 600 GeV at the 10 sigma level in an
effective exposure of 76 hr. We obtained a differential flux of
(5.0+/-1.5_{stat}+/-1.6_{sys})\times 10^{-12}(E/1 TeV)^{-\alpha}
cm^{-2}s^{-1}TeV^{-1} with a photon index \alpha of 2.69 +/- 0.30_{stat} +/-
0.34_{sys}, which is consistent with that of the H.E.S.S. observation in 2004.
We also confirm the extended morphology of the source. By combining our result
with multi-wavelength observations, we discuss the possible counterparts of
HESS J1804-216 and the radiation mechanism based on leptonic and hadronic
processes for a supernova remnant and a pulsar wind nebula.Comment: 11 pages, 12 figures, Accepted in Ap
Search for TeV gamma-rays from SN 1987A in 2001
We searched for TeV gamma-rays from the remnant of SN 1987A around 5400 days
after the supernova. The observations were carried out in 2001, from November
16 to December 11, using the CANGAROO-II Imaging Atmospheric Cherenkov
Telescope. In total, 708 minutes of ON- and 1019 minutes of OFF-source data
were obtained under good conditions. The detection threshold was estimated to
be 1 TeV, due to the mean zenith angle of 39. The upper limits for the
gamma-ray flux were obtained and compared with the previous observations and
theoretical models. The observations indicate that the gamma-ray luminosity is
lower than erg s at TeV.Comment: 8 pages, 3 figures, submitted for publication, style file adde
Detection of diffuse TeV gamma-ray emission from the nearby starburst galaxy NGC 253
We report the TeV gamma-ray observations of the nearby normal spiral galaxy
NGC 253. At a distance of 2.5 Mpc, NGC 253 is one of the nearest
starburst galaxies. This relative closeness, coupled with the high star
formation rate in the galaxy, make it a good candidate TeV gamma-ray source.
Observations were carried out in 2000 and 2001 with the CANGAROO-II 10 m
imaging atmospheric Cerenkov telescope. TeV gamma-ray emission is detected at
the level with a flux of at energies 0.5 TeV. The data indicate that the
emission region is broader than the point spread function of our telescope.Comment: 4 pages, double colomn, 3 figures, aa.cl
CANGAROO-III Observation of TeV Gamma Rays from the vicinity of PSR B1 706-44
Observation by the CANGAROO-III stereoscopic system of the Imaging Cherenkov
Telescope has detected extended emission of TeV gamma rays in the vicinity of
the pulsar PSR B170644. The strength of the signal observed as
gamma-ray-like events varies when we apply different ways of emulating
background events. The reason for such uncertainties is argued in relevance to
gamma-rays embedded in the "off-source data", that is, unknown sources and
diffuse emission in the Galactic plane, namely, the existence of a complex
structure of TeV gamma-ray emission around PSR B170644.Comment: 10 pages, 13 figures, to be published in Ap
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