374 research outputs found
Comment on Mie Scattering from a Sonoluminescing Bubble with High Spatial and Temporal Resolution [Physical Review E 61, 5253 (2000)]
A key parameter underlying the existence of sonoluminescence (SL)is the time
relative to SL at which acoustic energy is radiated from the collapsed bubble.
Light scattering is one route to this quantity. We disagree with the statement
of Gompf and Pecha that -highly compressed water causes the minimum in
scattered light to occur 700ps before SL- and that this effect leads to an
overestimate of the bubble wall velocity. We discuss potential artifacts in
their experimental arrangement and correct their description of previous
experiments on Mie scattering.Comment: 10 pages, 2 figure
Differential criterion of a bubble collapse in viscous liquids
The present work is devoted to a model of bubble collapse in a Newtonian
viscous liquid caused by an initial bubble wall motion. The obtained bubble
dynamics described by an analytic solution significantly depends on the liquid
and bubble parameters. The theory gives two types of bubble behavior: collapse
and viscous damping. This results in a general collapse condition proposed as
the sufficient differential criterion. The suggested criterion is discussed and
successfully applied to the analysis of the void and gas bubble collapses.Comment: 5 pages, 3 figure
Mechanisms for Stable Sonoluminescence
A gas bubble trapped in water by an oscillating acoustic field is expected to
either shrink or grow on a diffusive timescale, depending on the forcing
strength and the bubble size. At high ambient gas concentration this has long
been observed in experiments. However, recent sonoluminescence experiments show
that in certain circumstances when the ambient gas concentration is low the
bubble can be stable for days. This paper presents mechanisms leading to
stability which predict parameter dependences in agreement with the
sonoluminescence experiments.Comment: 4 pages, 3 figures on request (2 as .ps files
An Alternative Method to Deduce Bubble Dynamics in Single Bubble Sonoluminescence Experiments
In this paper we present an experimental approach that allows to deduce the
important dynamical parameters of single sonoluminescing bubbles (pressure
amplitude, ambient radius, radius-time curve) The technique is based on a few
previously confirmed theoretical assumptions and requires the knowledge of
quantities such as the amplitude of the electric excitation and the phase of
the flashes in the acoustic period. These quantities are easily measurable by a
digital oscilloscope, avoiding the cost of expensive lasers, or ultrafast
cameras of previous methods. We show the technique on a particular example and
compare the results with conventional Mie scattering. We find that within the
experimental uncertainties these two techniques provide similar results.Comment: 8 pages, 5 figures, submitted to Phys. Rev.
Nature of Sonoluminescence: Noble Gas Radiation Excited by Hot Electrons in "Cold" Water
We show that strong electric fields occurring in water near the surface of
collapsing gas bubbles because of the flexoelectric effect can provoke dynamic
electric breakdown in a micron-size region near the bubble and consider the
scenario of the SBSL. The scenario is: (i) at the last stage of incomplete
collapse of the bubble the gradient of pressure in water near the bubble
surface has such a value and sign that the electric field arising from the
flexoelectric effect exceeds the threshold field of the dynamic electrical
breakdown of water and is directed to the bubble center; (ii) mobile electrons
are generated because of thermal ionization of water molecules near the bubble
surface; (iii) these electrons are accelerated in ''cold'' water by the strong
electric fields; (iv) these hot electrons transfer noble gas atoms dissolved in
water to high-energy excited states and optical transitions between these
states produce SBSL UV flashes in the trasparency window of water; (v) the
breakdown can be repeated several times and the power and duration of the UV
flash are determined by the multiplicity of the breakdowns. The SBSL spectrum
is found to resemble a black-body spectrum where temperature is given by the
effective temperature of the hot electrons. The pulse energy and some other
characteristics of the SBSL are found to be in agreement with the experimental
data when realistic estimations are made.Comment: 11 pages (RevTex), 1 figure (.ps
Modelling mutational landscapes of human cancers in vitro
Experimental models that recapitulate mutational landscapes of human cancers are needed to decipher the
rapidly expanding data on human somatic mutations. We demonstrate that mutation patterns in
immortalised cell lines derived from primary murine embryonic fibroblasts (MEFs) exposed in vitro to
carcinogens recapitulate key features of mutational signatures observed in human cancers. In experiments
with several cancer-causing agents we obtained high genome-wide concordance between human tumour
mutation data and in vitro data with respect to predominant substitution types, strand bias and sequence
context. Moreover, we found signature mutations in well-studied human cancer driver genes. To explore
endogenous mutagenesis, we used MEFs ectopically expressing activation-induced cytidine deaminase
(AID) and observed an excess of AID signature mutations in immortalised cell lines compared to their
non-transgenic counterparts. MEF immortalisation is thus a simple and powerful strategy for modelling
cancer mutation landscapes that facilitates the interpretation of human tumour genome-wide sequencing
data
A Three-Dimensional Atlas of the Honeybee Neck
Three-dimensional digital atlases are rapidly becoming indispensible in modern biology. We used serial sectioning combined with manual registration and segmentation of images to develop a comprehensive and detailed three-dimensional atlas of the honeybee head-neck system. This interactive atlas includes skeletal structures of the head and prothorax, the neck musculature, and the nervous system. The scope and resolution of the model exceeds atlases previously developed on similar sized animals, and the interactive nature of the model provides a far more accessible means of interpreting and comprehending insect anatomy and neuroanatomy
Single-Vesicle Fusion Assay Reveals Munc18-1 Binding to the SNARE Core Is Sufficient for Stimulating Membrane Fusion
Intraepithelial CD8+ T-cell-count becomes a prognostic factor after a longer follow-up period in human colorectal carcinoma: possible association with suppression of micrometastasis
- …