Analysis of Tourism Service Quality in Kołobrzeg Region by Means of Time Series Models

The undertaken study shows that methods that take into account time series can be successfully used in analysis of parameters of tourist comfort and in evaluation of hotel services.Przeprowadzone badania wskazują, że metody szeregów czasowych mogą być skutecznie zastosowane w badaniu wskaźników turystycznych i ocenie jakości usług hotelarskich

Real-time detection of dictionary DGA network traffic using deep learning

Botnets and malware continue to avoid detection by static rules engines when using domain generation algorithms (DGAs) for callouts to unique, dynamically generated web addresses. Common DGA detection techniques fail to reliably detect DGA variants that combine random dictionary words to create domain names that closely mirror legitimate domains. To combat this, we created a novel hybrid neural network, Bilbo the `bagging` model, that analyses domains and scores the likelihood they are generated by such algorithms and therefore are potentially malicious. Bilbo is the first parallel usage of a convolutional neural network (CNN) and a long short-term memory (LSTM) network for DGA detection. Our unique architecture is found to be the most consistent in performance in terms of AUC, F1 score, and accuracy when generalising across different dictionary DGA classification tasks compared to current state-of-the-art deep learning architectures. We validate using reverse-engineered dictionary DGA domains and detail our real-time implementation strategy for scoring real-world network logs within a large financial enterprise. In four hours of actual network traffic, the model discovered at least five potential command-and-control networks that commercial vendor tools did not flag

A case of iliac crest avulsion with peritoneal disruption and bowel herniation after blunt trauma

Pelvic fractures account for approximately 3% of all blunt traumatic skeletal injuries. Pelvic fractures are most commonly caused by motor vehicle accidents (60%), falls from a height (30%), and crush injuries (10%). Pelvic fractures are a marker for high-energy trauma and are often associated with other life-threatening injuries. Over 80% of patients with unstable pelvic fractures will be found to have additional musculoskeletal injuries. Although the mortality rate in patients with pelvic fractures has been declining in recent years due to the robustness of the US trauma system, the incidence is increasing due to the higher rate of high-speed motor vehicle collisions

‘Door-To-Prophylaxis’ as a Novel Quality Improvement Metric in Prevention of Venous Thromboembolism Following Traumatic Injury

OBJECTIVE: Venous thromboembolism (VTE) risk reduction strategies include early initiation of chemoprophylaxis, reducing missed doses, weight-based dosing and dose adjustment using anti-Xa levels. We hypothesized that time to initiation of chemoprophylaxis would be the strongest modifiable risk for VTE, even after adjusting for competing risk factors. METHODS: A prospectively maintained trauma registry was queried for patients admitted July 2017-October 2021 who were 18 years and older and received emergency release blood products. Patients with deep vein thrombosis or pulmonary embolism (VTE) were compared to those without (no VTE). Door-to-prophylaxis was defined as time from hospital arrival to first dose of VTE chemoprophylaxis (hours). Univariate and multivariate analyses were then performed between the two groups. RESULTS: 2047 patients met inclusion (106 VTE, 1941 no VTE). There were no differences in baseline or demographic data. VTE patients had higher injury severity score (29 vs 24), more evidence of shock by arrival lactate (4.6 vs 3.9) and received more post-ED transfusions (8 vs 2 units); all p CONCLUSION: The current retrospective study of severely injured patients with trauma who required emergency release blood products found that increased door-to-prophylaxis time was significantly associated with an increased likelihood for VTE. Chemoprophylaxis initiation is one of the few modifiable risk factors available to combat VTE, therefore early initiation is paramount. Similar to door-to-balloon time in treating myocardial infarction and door-to-tPA time in stroke, door-to-prophylaxis time should be considered as a hospital metric for prevention of VTE in trauma. LEVEL OF EVIDENCE: Level III, retrospective study with up to two negative criteria

Ponzano-Regge model revisited I: Gauge fixing, observables and interacting spinning particles

We show how to properly gauge fix all the symmetries of the Ponzano-Regge model for 3D quantum gravity. This amounts to do explicit finite computations for transition amplitudes. We give the construction of the transition amplitudes in the presence of interacting quantum spinning particles. We introduce a notion of operators whose expectation value gives rise to either gauge fixing, introduction of time, or insertion of particles, according to the choice. We give the link between the spin foam quantization and the hamiltonian quantization. We finally show the link between Ponzano-Regge model and the quantization of Chern-Simons theory based on the double quantum group of SU(2)Comment: 48 pages, 15 figure

BRAHMA ATPase of the SWI/SNF Chromatin Remodeling Complex Acts as a Positive Regulator of Gibberellin-Mediated Responses in Arabidopsis

SWI/SNF chromatin remodeling complexes perform a pivotal function in the regulation of eukaryotic gene expression. Arabidopsis (Arabidopsis thaliana) mutants in major SWI/SNF subunits display embryo-lethal or dwarf phenotypes, indicating their critical role in molecular pathways controlling development and growth. As gibberellins (GA) are major positive regulators of plant growth, we wanted to establish whether there is a link between SWI/SNF and GA signaling in Arabidopsis. This study revealed that in brm-1 plants, depleted in SWI/SNF BRAHMA (BRM) ATPase, a number of GA-related phenotypic traits are GA-sensitive and that the loss of BRM results in markedly decreased level of endogenous bioactive GA. Transcriptional profiling of brm-1 and the GA biosynthesis mutant ga1-3, as well as the ga1-3/brm-1 double mutant demonstrated that BRM affects the expression of a large set of GA-responsive genes including genes responsible for GA biosynthesis and signaling. Furthermore, we found that BRM acts as an activator and directly associates with promoters of GA3ox1, a GA biosynthetic gene, and SCL3, implicated in positive regulation of the GA pathway. Many GA-responsive gene expression alterations in the brm-1 mutant are likely due to depleted levels of active GAs. However, the analysis of genetic interactions between BRM and the DELLA GA pathway repressors, revealed that BRM also acts on GA-responsive genes independently of its effect on GA level. Given the central position occupied by SWI/SNF complexes within regulatory networks controlling fundamental biological processes, the identification of diverse functional intersections of BRM with GA-dependent processes in this study suggests a role for SWI/SNF in facilitating crosstalk between GA-mediated regulation and other cellular pathways

A variational method based on weighted graph states

In a recent article [Phys. Rev. Lett. 97 (2006), 107206], we have presented a class of states which is suitable as a variational set to find ground states in spin systems of arbitrary spatial dimension and with long-range entanglement. Here, we continue the exposition of our technique, extend from spin 1/2 to higher spins and use the boson Hubbard model as a non-trivial example to demonstrate our scheme.Comment: 36 pages, 13 figure

Diagnosing collaboration in practice-based learning: Equality and intra-individual variability of physical interactivity

Collaborative problem solving (CPS), as a teaching and learning approach, is considered to have the potential to improve some of the most important skills to prepare students for their future. CPS often differs in its nature, practice, and learning outcomes from other kinds of peer learning approaches, including peer tutoring and cooperation; and it is important to establish what identifies collaboration in problem-solving situations. The identification of indicators of collaboration is a challenging task. However, students physical interactivity can hold clues of such indicators. In this paper, we investigate two non-verbal indexes of student physical interactivity to interpret collaboration in practice-based learning environments: equality and intra-individual variability. Our data was generated from twelve groups of three Engineering students working on open-ended tasks using a learning analytics system. The results show that high collaboration groups have member students who present high and equal amounts of physical interactivity and low and equal amounts of intra-individual variability

Quantum Gravity in 2+1 Dimensions: The Case of a Closed Universe

In three spacetime dimensions, general relativity drastically simplifies, becoming a ``topological'' theory with no propagating local degrees of freedom. Nevertheless, many of the difficult conceptual problems of quantizing gravity are still present. In this review, I summarize the rather large body of work that has gone towards quantizing (2+1)-dimensional vacuum gravity in the setting of a spatially closed universe.Comment: 61 pages, draft of review for Living Reviews; comments, criticisms, additions, missing references welcome; v2: minor changes, added reference