Effect of fungal interactions on the numbers of the pinewood nematode, Bursaphelenchus xylophilus (Nematoda : Aphelenchoididae), carried by the japanese pine sawyer, Monochamus alternatus (Coleoptera : Cerambycidae)

#Monochamus alternatus sortant de blocs de bois préalablement inoculés avec #Ophiostoma minus et ensuite avec #Trichoderma sp. (O + T) transporte un plus grand nombre de #Bursaphelenchus xylophilus (PWN) que ceux sortant de blocs inoculés simultanément avec ces deux champignons (O, T) ou inoculés avec #Trichoderma sp. puis avec #O. minus (T + O). La raison est que : les populations de PWN sont plus élevées dans les blocs O + T que dans ceux des autres traitements, et que le pourcentage de juvéniles de dispersion de 3ème stade, les "dauer" juvéniles et les PWN qui passent réellement dans l'insecte sont plus nombreux dans les blocs O + T. En contraste, le nombre de PWN transportés par l'insecte sortant de blocs inoculés avec #O. minus et #Verticillium sp. est beaucoup moins élevé quelle que soit la séquence d'innoculum parce que les populations de PWN ne s'établissent pas. Il est conclu que les espèces de champignon les plus abondantes dans les pins tués par le dessèchement concourent à déterminer le nombre de PWN transportés par l'insecte sortant du bois. (Résumé d'auteur

KIC 4150611: a rare multi-eclipsing quintuple with a hybrid pulsator

We present the results of our analysis of KIC 4150611 (HD 181469) - an interesting, bright quintuple system that includes a hybrid $\delta$ Sct/$\gamma$ Dor pulsator. Four periods of eclipses - 94.2, 8.65, 1.52 and 1.43 d - have been observed by the Kepler satellite, and three point sources (A, B, and C) are seen in high angular resolution images. From spectroscopic observations made with the HIDES spectrograph attached to the 1.88-m telescope of the Okayama Astrophysical Observatory (OAO), for the first time we calculated radial velocities (RVs) of the component B - a pair of G-type stars - and combined them with Kepler photometry in order to obtain absolute physical parameters of this pair. We also managed to directly measure RVs of the pulsator, also for the first time. Additionally, we modelled the light curves of the 1.52 and 1.43-day pairs, and measured their eclipse timing variations (ETVs). We also performed relative astrometry and photometry of three sources seen on the images taken with the NIRC2 camera of the Keck II telescope. Finally, we compared our results with theoretical isochrones. The brightest component Aa is the hybrid pulsator, transited every 94.2 days by a pair of K/M-type stars (Ab1+Ab2), which themselves form a 1.52-day eclipsing binary. The components Ba and Bb are late G-type stars, forming another eclipsing pair with a 8.65 day period. Their masses and radii are $M_{Ba}=0.894\pm0.010$ M$_\odot$, $R_{Ba}=0.802\pm0.044$ R$_\odot$ for the primary, and $M_{Bb}=0.888\pm0.010$ M$_\odot$, $R_{Bb}=0.856\pm0.038$ R$_\odot$ for the secondary. The remaining period of 1.43 days is possibly related to a faint third star C, which itself is most likely a background object. The system's properties are well-represented by a 35 Myr isochrone. There are also hints of additional bodies in the system.Comment: 14 pages, 15 figures, 7 tables, to appear in A&A, abstract modified in order to fit the arXiv limi

Optical and CO Radio Observations of Poor Cluster Zwicky 1615.8+3505

The cluster Zwicky 1615.8+3505 is considered to be a dynamically young poor cluster. To investigate the morphology and star-formation activity of galaxies under the environment of a dynamically young poor cluster, we have performed V, R, and I surface photometry, optical low-resolution spectroscopy, and 12CO (J=1-0) line observations for member galaxies. Our data show that more than 90% of the observed galaxies show regular morphologies and no star-formation activities, indicating that the environment does not affect these galaxy properties. Among sixteen galaxies observed, only NGC 6104 shows a significant star-formation activity, and shows a distorted morphology, indicating a tidal interaction. This galaxy contains double knots, and only one knot possesses Seyfert activity, though the sizes and luminosities are similar to each other; we also discuss this feature.Comment: LaTeX manuscript (text.tex, use PASJ style files), four PS figures (fig[a-d].ps), and three PASJ style files. text.tex, figb.ps, and figd.ps are up-dated. To be appeared in The Publications of the Astronomical Society of Japan, Vol. 51, No. 3 (1999 June issue

NK4, a four-kringle antagonist of HGF, inhibits spreading and invasion of human pancreatic cancer cells

Because of the highly aggressive behaviour, i.e. invasive, disseminative and metastatic properties, the outcome for patients with pancreatic cancer is morbid. A better understanding and interference with the malignant behaviour of pancreatic cancer may provide new directions for treatment. We report here the induction of highly motile and invasive properties in human pancreatic cancer cells by hepatocyte growth factor (HGF) and blockage of these properties by NK4, a newly identified antagonist for HGF. In all of eight human pancreatic cancer cell lines we used (AsPC-1, BxPC-3, H-48N, KP-1N, KP-2, KP-3, MIA PaCa-2 and SUIT-2 cells), the c-Met/HGF receptor was expressed at varying levels. Although weak mitogenic activity of HGF was seen only in SUIT-2 and KP-3 cells, HGF strongly stimulated migration and invasion of these pancreatic cancer cells, except for BxPC-3 and MIA PaCa-2 cells. In contrast, migration and invasion potently induced by HGF in KP-1N, KP-3 and SUIT-2 cells were inhibited by NK4. The invasion of SUIT-2 cells was also potently stimulated with the influence of cocultured pancreatic fibroblasts and by ascitic fluid obtained after pancreatic cancer resection, however, invasiveness of the cancer cells in such conditions was practically abolished by NK4. Consistently, the ascitic fluid in patients who had undergone pancreatic cancer surgery contained high levels of HGF. These findings mean that HGF is probably involved in invasion, dissemination, and metastasis of pancreatic cancer, particularly through tumour-stromal interaction and after resection of the pancreatic cancer. NK4, an effective antagonist of HGF, may prove to have the potential for anti-invasion/metastasis. © 2001 Cancer Research Campaign http://www.bjcancer.co

The strong thirteen spheres problem

The thirteen spheres problem is asking if 13 equal size nonoverlapping spheres in three dimensions can touch another sphere of the same size. This problem was the subject of the famous discussion between Isaac Newton and David Gregory in 1694. The problem was solved by Schutte and van der Waerden only in 1953. A natural extension of this problem is the strong thirteen spheres problem (or the Tammes problem for 13 points) which asks to find an arrangement and the maximum radius of 13 equal size nonoverlapping spheres touching the unit sphere. In the paper we give a solution of this long-standing open problem in geometry. Our computer-assisted proof is based on a enumeration of the so-called irreducible graphs.Comment: Modified lemma 2, 16 pages, 12 figures. Uploaded program packag

Dynamical Generation of CKM Mixings by Broken Horizontal Gauge Interactions

The fermion mass matrices are calculated in the framework of the dynamical mass generation by the broken horizontal gauge interactions. The non-proportional mass spectra between up- and down-sectors and CKM mixings are obtained solely by radiative corrections due to the ordinary gauge interactions.Comment: 20 pages + 1 uuencoded eps figure, PHYZZ

Study on Control Performance of HVAC System or Interior Zone and Perimeter Zone in Office Building; Estimation of Optimal PI Tuning in Cooling Operation

In office buildings there are generally two HVAC systems installed, one in the perimeter zone (PZ) and one in the interior zone (IZ), and the temperatures of each zone are independently controlled. In the present paper, in order to the solve problem of not being able to satisfy the requirements of room temperature control during the cooling period in summer, an optimal PID parameter (O-PI) is selected through simulation of its two feedback control systems with mutual influence using the models identified with the experimental data. The step response characteristics of the system with optimal parameters compared to those with the parameters selected by the Ziegler-Nichols Method (ZNM-PI) that are generally used for PID parameter tuning on site. The result shows O-PI improved control performance, and the difference between O-PI and ZNM-PI can be used to readjust ZNM-PI selected on site