2,011 research outputs found
Dynamics of Social Balance on Networks
We study the evolution of social networks that contain both friendly and
unfriendly pairwise links between individual nodes. The network is endowed with
dynamics in which the sense of a link in an imbalanced triad--a triangular loop
with 1 or 3 unfriendly links--is reversed to make the triad balanced. With this
dynamics, an infinite network undergoes a dynamic phase transition from a
steady state to "paradise"--all links are friendly--as the propensity p for
friendly links in an update event passes through 1/2. A finite network always
falls into a socially-balanced absorbing state where no imbalanced triads
remain. If the additional constraint that the number of imbalanced triads in
the network does not increase in an update is imposed, then the network quickly
reaches a balanced final state.Comment: 10 pages, 7 figures, 2-column revtex4 forma
Особенности налогообложения в розничной торговле
Объектом исследования является: ИП Хорева специализирующееся на розничной торговле изделиями из меха и кожи. Цель работы – анализ деятельности предприятия, определение основных показателей его экономической деятельности, расчет налогов, расчет и анализ налоговой нагрузки предприятия. В процессе исследования проводились: создание теоретической базы для анализа экономической деятельности предприятия, непосредственно анализ экономической деятельности, расчёт и анализ налоговой нагрузки предприятия. В результате исследования выработаны конкретные рекомендации по оптимизации экономической деятельности предприятия.The object of research is: IP Khoreva specializing in the retail sale of fur and leather products. The purpose of the work is the analysis of the enterprise, determining the main indicators of its economic activity, tax calculation, calculation and analysis of the tax burden of the enterprise. In the course of the research, the following was carried out: creation of a theoretical base for analysis of the economic activity of an enterprise, direct analysis of economic activity, calculation and analysis of the tax burden of the enterprise. As a result of the study, specific recommendations were developed to optimize the economic activity of the enterprise
Influence of heated forming tools on corrosion behavior of high strength aluminum alloys
In this study forming tools temperated at 24 °C and 350 °C were used to systematically investigate the influence of different cooling rates on the mechanical and corrosion properties of a high strength aluminum alloy AA7075 within a novel thermo‐mechanical process that combines forming and quenching simultaneously. The samples formed within heated tools reveal higher ductility and lower material strength compared to the parts processed in cold tools. In addition, the corrosion behavior changed between samples formed with 24 °C forming tools and 350 °C forming tools, respectively. Through cyclic polarization in chloride containing aqueous media a change in the hysteresis and shift of open circuit potential was observed. Metallographic investigation revealed that there was also a very different corrosion morphology for the samples formed within the heated tools. No change in average grain size could be detected but changes of the microstructure in subgrain scale that occur during the forming within the heated tools are responsible for this effect. In further research, the effect of various cooling rates on mechanical and corrosion behavior and the microstructure will be investigated by variation of the forming tool temperature
Dark Matter Spin-Dependent Limits for WIMP Interactions on 19-F by PICASSO
The PICASSO experiment at SNOLAB reports new results for spin-dependent WIMP
interactions on F using the superheated droplet technique. A new
generation of detectors and new features which enable background discrimination
via the rejection of non-particle induced events are described. First results
are presented for a subset of two detectors with target masses of F of
65 g and 69 g respectively and a total exposure of 13.75 0.48 kgd. No
dark matter signal was found and for WIMP masses around 24 GeV/c new limits
have been obtained on the spin-dependent cross section on F of
= 13.9 pb (90% C.L.) which can be converted into cross section
limits on protons and neutrons of = 0.16 pb and = 2.60 pb
respectively (90% C.L). The obtained limits on protons restrict recent
interpretations of the DAMA/LIBRA annual modulations in terms of spin-dependent
interactions.Comment: Revised version, accepted for publication in Phys. Lett. B, 20 pages,
7 figure
A Relational Event Approach to Modeling Behavioral Dynamics
This chapter provides an introduction to the analysis of relational event
data (i.e., actions, interactions, or other events involving multiple actors
that occur over time) within the R/statnet platform. We begin by reviewing the
basics of relational event modeling, with an emphasis on models with piecewise
constant hazards. We then discuss estimation for dyadic and more general
relational event models using the relevent package, with an emphasis on
hands-on applications of the methods and interpretation of results. Statnet is
a collection of packages for the R statistical computing system that supports
the representation, manipulation, visualization, modeling, simulation, and
analysis of relational data. Statnet packages are contributed by a team of
volunteer developers, and are made freely available under the GNU Public
License. These packages are written for the R statistical computing
environment, and can be used with any computing platform that supports R
(including Windows, Linux, and Mac).
Aberrant Lipid Metabolism in the Forebrain Niche Suppresses Adult Neural Stem Cell Proliferation in an Animal Model of Alzheimer’s Disease
SummaryLipid metabolism is fundamental for brain development and function, but its roles in normal and pathological neural stem cell (NSC) regulation remain largely unexplored. Here, we uncover a fatty acid-mediated mechanism suppressing endogenous NSC activity in Alzheimer’s disease (AD). We found that postmortem AD brains and triple-transgenic Alzheimer’s disease (3xTg-AD) mice accumulate neutral lipids within ependymal cells, the main support cell of the forebrain NSC niche. Mass spectrometry and microarray analyses identified these lipids as oleic acid-enriched triglycerides that originate from niche-derived rather than peripheral lipid metabolism defects. In wild-type mice, locally increasing oleic acid was sufficient to recapitulate the AD-associated ependymal triglyceride phenotype and inhibit NSC proliferation. Moreover, inhibiting the rate-limiting enzyme of oleic acid synthesis rescued proliferative defects in both adult neurogenic niches of 3xTg-AD mice. These studies support a pathogenic mechanism whereby AD-induced perturbation of niche fatty acid metabolism suppresses the homeostatic and regenerative functions of NSCs
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