A Chandra−SwiftChandra-Swift View of Point Sources in Hickson Compact Groups: High AGN fraction but a dearth of strong AGNs

We present $Chandra$ X-ray point source catalogs for 9 Hickson Compact Groups (HCGs, 37 galaxies) at distances $34 - 89$ Mpc. We perform detailed X-ray point source detection and photometry, and interpret the point source population by means of simulated hardness ratios. We thus estimate X-ray luminosities ($L_X$) for all sources, most of which are too weak for reliable spectral fitting. For all sources, we provide catalogs with counts, count rates, power-law indices ($\Gamma$), hardness ratios, and $L_X$, in the full ($0.5-8.0$ keV), soft ($0.5-2.0$ keV) and hard ($2.0-8.0$ keV) bands. We use optical emission-line ratios from the literature to re-classify 24 galaxies as star-forming, accreting onto a supermassive black hole (AGNs), transition objects, or low-ionization nuclear emission regions (LINERs). Two-thirds of our galaxies have nuclear X-ray sources with $Swift$/UVOT counterparts. Two nuclei have $L_{X,{\rm 0.5-8.0 keV}}$~$> 10^{42}$ erg s$^{-1}$, are strong multi-wavelength AGNs and follow the known $\alpha_{\rm OX}-\nu L_{\nu,\rm near UV}$ correlation for strong AGNs. Otherwise, most nuclei are X-ray faint, consistent with either a low-luminosity AGN or a nuclear X-ray binary population, and fall in the "non-AGN locus" in $\alpha_{\rm OX}-\nu L_{\nu,\rm near UV}$ space, which also hosts other, normal, galaxies. Our results suggest that HCG X-ray nuclei in high specific star formation rate spiral galaxies are likely dominated by star formation, while those with low specific star formation rates in earlier types likely harbor a weak AGN. The AGN fraction in HCG galaxies with $M_R \le -20$ and $L_{X,{\rm 0.5-8.0 keV}} \ge 10^{41}$ erg s$^{-1}$ is $0.08^{+0.35}_{-0.01}$, somewhat higher than the $\sim 5$ fraction in galaxy clusters.Comment: 77 pages (emulateapj), 28 tables, 11 figures. Accepted by ApJS on March 5, 201

Exploring X-ray Binary Populations in Compact Group Galaxies with ChandraChandra

We obtain total galaxy X-ray luminosities, $L_X$, originating from individually detected point sources in a sample of 47 galaxies in 15 compact groups of galaxies (CGs). For the great majority of our galaxies, we find that the detected point sources most likely are local to their associated galaxy, and are thus extragalactic X-ray binaries (XRBs) or nuclear active galactic nuclei (AGNs). For spiral and irregular galaxies, we find that, after accounting for AGNs and nuclear sources, most CG galaxies are either within the $\pm1\sigma$ scatter of the Mineo et al. (2012) $L_X$ - star formation rate (SFR) correlation or have higher $L_X$ than predicted by this correlation for their SFR. We discuss how these "excesses" may be due to low metallicities and high interaction levels. For elliptical and S0 galaxies, after accounting for AGNs and nuclear sources, most CG galaxies are consistent with the Boroson et al. (2011) $L_X$ - stellar mass correlation for low-mass XRBs, with larger scatter, likely due to residual effects such as AGN activity or hot gas. Assuming non-nuclear sources are low- or high-mass XRBs, we use appropriate XRB luminosity functions to estimate the probability that stochastic effects can lead to such extreme $L_X$ values. We find that, although stochastic effects do not in general appear to be important, for some galaxies there is a significant probability that high $L_X$ values can be observed due to strong XRB variability.Comment: Accepted by Ap

Stellar Populations in Compact Galaxy Groups: a Multi-Wavelength Study of HCGs 16, 22, and 42, their Star Clusters and Dwarf Galaxies

We present a multi-wavelength analysis of three compact galaxy groups, HCGs 16, 22, and 42, which describe a sequence in terms of gas richness, from space- (Swift, HST, Spitzer) and ground-based (LCO, CTIO) imaging and spectroscopy. We study various signs of past interactions including a faint, dusty tidal feature about HCG 16A, which we tentatively age-date at <1 Gyr. This represents the possible detection of a tidal feature at the end of its phase of optical observability. Our HST images also resolve what were thought to be double nuclei in HCG 16C and D into multiple, distinct sources, likely to be star clusters. Beyond our phenomenological treatment, we focus primarily on contrasting the stellar populations across these three groups. The star clusters show a remarkable intermediate-age population in HCG 22, and identify the time at which star formation was quenched in HCG 42. We also search for dwarf galaxies at accordant redshifts. The inclusion of 33 members and 27 'associates' (possible members) radically changes group dynamical masses, which in turn may affect previous evolutionary classifications. The extended membership paints a picture of relative isolation in HCGs 16 and 22, but shows HCG 42 to be part of a larger structure, following a dichotomy expected from recent studies. We conclude that (a) star cluster populations provide an excellent metric of evolutionary state, as they can age-date the past epochs of star formation; and (b) the extended dwarf galaxy population must be considered in assessing the dynamical state of a compact group.Comment: 29 pages, 13 figures. Accepted for publication in The Astrophysical Journa

Existence of global strong solutions to a beam-fluid interaction system

We study an unsteady non linear fluid-structure interaction problem which is a simplified model to describe blood flow through viscoleastic arteries. We consider a Newtonian incompressible two-dimensional flow described by the Navier-Stokes equations set in an unknown domain depending on the displacement of a structure, which itself satisfies a linear viscoelastic beam equation. The fluid and the structure are fully coupled via interface conditions prescribing the continuity of the velocities at the fluid-structure interface and the action-reaction principle. We prove that strong solutions to this problem are global-in-time. We obtain in particular that contact between the viscoleastic wall and the bottom of the fluid cavity does not occur in finite time. To our knowledge, this is the first occurrence of a no-contact result, but also of existence of strong solutions globally in time, in the frame of interactions between a viscous fluid and a deformable structure

Multispectral tissue mapping: developing a concept for the optical evaluation of liver disease

Purpose: Alterations in the optical absorption behavior of liver tissue secondary to pathological processes can be evaluated by multispectral analysis, which is increasingly being explored as an imaging adjunct for use in liver surgery. Current methods are either invasive or have a limited wavelength spectrum, which restricts utility. This proof of concept study describes the development of a multispectral imaging (MSI) method called multispectral tissue mapping (MTM) that addresses these issues. Approach: The imaging system consists of a tunable excitation light source and a near-infrared camera. Following the development stage, proof of concept experiments are carried out where absorption spectra from colorectal cancer liver metastasis (CRLM), hepatocellular carcinoma (HCC), and liver steatosis specimen are acquired and compared to controls. Absorption spectra are compared to histopathology examination as the current gold standard for tissue assessment. Generalized linear mixed modeling is employed to compare absorption characteristics of individual pixels and to select wavelengths for false color image processing with the aim of visually enhancing cancer tissue. Results: Analysis of individual pixels revealed distinct absorption spectra therefore suggesting that MTM is possible. A prominent absorption peak at 1210 nm was found in lipid-rich animal tissues and steatotic liver specimen. Liver cancer tissue had a heterogeneous appearance on MSI. Subsequent statistical analysis suggests that measuring changes in absorption behavior may be a feasible method to estimate the pixel-based probability of cancer being present. In CRLM, this was observed throughout 1100 to 1700 nm, whereas in HCC it was concentrated around 1140 and 1430 nm. False color image processing visibly enhances contrast between cancer and normal liver tissues. Conclusions: The system’s ability to enable no-touch MSI at 1100 to 1700 nm was demonstrated. Preliminary data suggest that MTM warrants further exploration as a potential imaging tool for the detection of liver cancer during surger

Identification of liver metastases with probe-based confocal laser endomicroscopy at two excitation wavelengths.

BACKGROUND: Metastasis of colorectal cancer to the liver is the most common indication for hepatic resection in a western population. Incomplete excision of malignancy due to residual microscopic disease normally results in worse patient outcome. Therefore, a method aiding in the real time discrimination of normal and malignant tissue on a microscopic level would be of benefit. MATERIAL AND METHODS: The ability of fluorescent probe-based confocal laser endomicroscopy (pCLE) to identify normal and malignant liver tissue was evaluated in an orthotopic murine model of colorectal cancer liver metastasis (CRLM). To maximise information yield, two clinical fluorophores, fluorescein and indocyanine green (ICG) were injected and imaged in a dual wavelength approach (488 and 660 nm, respectively). Visual tissue characteristics on pCLE examination were compared with histological features. Fluorescence intensity in both tissues was statistically analysed to elucidate if this can be used to differentiate between normal and malignant tissue. RESULTS: Fluorescein (488 nm) enabled good visualisation of normal and CRLM tissue, whereas ICG (660 nm) visualisation was limited to normal liver tissue only. Fluorescence intensity in areas of CRLM was typically 53-100% lower than normal hepatic parenchyma. Using general linear mixed modelling and receiver operating characteristic analysis, high fluorescence intensity was found to be statistically more likely in normal hepatic tissue. CONCLUSION: Real time discrimination between normal liver parenchyma and metastatic tissue with pCLE examination of fluorescein and ICG is feasible. Employing two (rather than a single) fluorophores allows a combination of qualitative and quantitative characteristics to be used to distinguish between hepatic parenchyma and CRLM. Lasers Surg. Med. © 2016 Wiley Periodicals, Inc

A Kato type Theorem for the inviscid limit of the Navier-Stokes equations with a moving rigid body

The issue of the inviscid limit for the incompressible Navier-Stokes equations when a no-slip condition is prescribed on the boundary is a famous open problem. A result by Tosio Kato says that convergence to the Euler equations holds true in the energy space if and only if the energy dissipation rate of the viscous flow in a boundary layer of width proportional to the viscosity vanishes. Of course, if one considers the motion of a solid body in an incompressible fluid, with a no-slip condition at the interface, the issue of the inviscid limit is as least as difficult. However it is not clear if the additional difficulties linked to the body's dynamic make this issue more difficult or not. In this paper we consider the motion of a rigid body in an incompressible fluid occupying the complementary set in the space and we prove that a Kato type condition implies the convergence of the fluid velocity and of the body velocity as well, what seems to indicate that an answer in the case of a fixed boundary could also bring an answer to the case where there is a moving body in the fluid

The motion of a fluid-rigid disc system at the zero limit of the rigid disc radius

We consider the two-dimensional motion of the coupled system of a viscous incompressible fluid and a rigid disc moving with the fluid, in the whole plane. The fluid motion is described by the Navier-Stokes equations and the motion of the rigid body by conservation laws of linear and angular momentum. We show that, assuming that the rigid disc is not allowed to rotate, as the radius of the disc goes to zero, the solution of this system converges, in an appropriate sense, to the solution of the Navier-Stokes equations describing the motion of only fluid in the whole plane. We also prove that the trajectory of the centre of the disc, at the zero limit of its radius, coincides with a fluid particle trajectory.Comment: 29 pages, 0 figure

Laparoscopic manipulation of a probe-based confocal laser endomicroscope using a steerable intravascular catheter.

Probe-based confocal laser endomicroscopy is an emerging imaging modality that enables visualization of histologic details during endoscopy and surgery. A method of guiding the probe with millimeter accuracy is required to enable imaging in all regions of the abdomen accessed during laparoscopy. On the basis of a porcine model of laparoscopic liver resection, we report our experience of using a steerable intravascular catheter to guide a probe-based confocal laser endomicroscope