2,190 research outputs found

    Leptonic decays of the eta meson with the WASA detector at CELSIUS

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    Decay channels of the eta meson with at least one lepton pair in the final state are discussed. Preliminary results on electron-positron pair production from the pd->He eta reaction from the WASA experiment at CELSIUS are presented.Comment: 8 pages, 7 figures, prepared for Symposium on Meson Physics at COSY-11 and WASA-at-COSY, Cracow, 17-22 June 200

    Changes in sleep duration, quality, and medication use are prospectively associated with health and well-being : analysis of the UK Household Longitudinal Study

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    Introduction: Sleep is a plausible target for public health promotion. We examined the association of changes in sleep with subsequent health and well-being in the general population. Aims and Methods: We analyzed data from the UK Household Longitudinal Survey, involving 30594 people (aged > 16) who provided data on sleep and health and well-being at both Wave 1 (2009–2011) and Wave 4 (2012–2014) assessments. Predicting variables were changes in sleep quantity, sleep quality, and sleep medication use over the 4-year period. Outcome variables were the General Health Questionnaire (GHQ-12) and the 12-Item Short-Form Health Survey (SF-12) mental (MCS) and physical (PCS) component scores at Wave 4. Linear regression on each outcome was fully adjusted for potential confounders and baseline values of the relevant predicting and outcome variables. Results: Better outcomes were associated with an increase in sleep duration (GHQ: β = 1.031 [95% confidence interval {CI}: −1.328, −0.734]; MCS: 1.531 [1.006, 2.055]; PCS: −0.071 [−0.419, 0.56]), sleep quality (GHQ: β = −2.031 [95% CI: −2.218, −1.844]; MCS: 3.027 [2.692, 3.361]; PCS: 0.924 [0.604, 1.245]), and a reduction in sleep medication use (GHQ: β = −1.929 [95% CI: −2.400, −1.459]; MCS: 3.106 [2.279, 3.933]; PCS: 2.633 [1.860, 3.406]). Poorer outcomes were on the other hand associated with a reduction in sleep duration, a decrease in sleep quality, and an increase in sleep medication use. Changes in sleep quality yielded the largest effects on the health and well-being outcomes. Conclusions: Changes in sleep were temporally associated with subsequent health and well-being. Initiatives that aim to protect a critical amount of sleep, promote sleep quality, and reduce sleep medication use may have public health values

    Sleep problems in childhood and borderline personality disorder symptoms in early adolescence

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    Sleep disorders, such as insomnia and nightmares, are commonly associated with Borderline Personality Disorder (BPD) in adulthood. Whether nightmares and sleep-onset and maintenance problems predate BPD symptoms earlier in development is unknown. We addressed this gap in the literature using data from the Avon Longitudinal Study of Parents and Children (ALSPAC). Participants included 6,050 adolescents (51.4% female) who completed the UK Childhood Interview for DSM-IV BPD at 11 to 12 years of age. Nightmares and sleep onset and maintenance problems were prospectively assessed via mother report when children were 2.5, 3.5, 4.8 and 6.8 years of age. Psychopathological (i.e., emotional temperament; psychiatric diagnoses; and emotional and behavioural problems) and psychosocial (i.e., abuse, maladaptive parenting, and family adversity) confounders were assessed via mother report. In logistic regressions, persistent nightmares (i.e., regular nightmares at three or more time-points) were significantly associated with BPD symptoms following adjustment for sleep onset and maintenance problems and all confounders (Adjusted Odds Ratio=1.67; 95% Confidence Interval=1.18, 2.38). Persistent sleep onset and maintenance problems were not significantly associated with BPD symptoms. In path analysis controlling for all associations between confounders, persistent nightmares independently predicted BPD symptoms (Probit co-efficient [β] = 0.08, p = 0.013). Emotional and behavioural problems significantly mediated the association between nightmares and BPD (β =0.016, p<0.001), while nightmares significantly mediated associations between emotional temperament (β=0.001, p=0.018), abuse (β=0.015, p=0.018), maladaptive parenting (β=0.002, p=0.021) and subsequent BPD. These findings tentatively support that childhood nightmares may potentially increase the risk of BPD symptoms in early adolescence via a number of aetiological pathways. If replicated, the current findings could have important implications for early intervention, and assist clinicians in the identification of children at risk of developing BPD

    Experimental results on strangeness production in proton-proton collisions at COSY

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    The production of K+ and K- mesons in elementary proton-proton collision has been investigated at the Cooler Synchrotron COSY in Juelich. A high quality proton beam with low emittance and small momentum spread permitted to study the creation of these mesons very close to the kinematical threshold. The energy dependence of the total cross section is investigated using internal beam facilities providing a high accuracy particle momentum determination as well as an external non-magnetic detection setup with a large geometrical acceptance. The determination of the four-momentum vectors for all ejectiles of each registered event gives the complete kinematical information allowing to study the interaction of the outgoing particles. Results on the performed studies of the pp --> pp K+ K-, pp --> p Lambda K+ and pp --> p Sigma0 K+ reactions will be presented and their relevance to the interpretation of heavy ion collisions will be discussed.Comment: 8 pages, 6 figures, plenary talk at 6th International Conference On Strange Quarks in Matter: '2001 - A Flavorspace Odyssey' (SQM2001), Frankfurt, Germany, September 25-29, 2001, to be published in J. Phys. G: Nucl. Part. Phy

    Investigating whether adverse prenatal and perinatal events are associated with non-clinical psychotic symptoms at age 12 years in the ALSPAC birth cohort

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    Background. Non-clinical psychosis-like symptoms (PLIKS) occur in about 15% of the population. It is not clear whether adverse events during early development alter the risk of developing PLIKS. We aimed to examine whether maternal infection, diabetes or pre-eclampsia during pregnancy, gestational age, perinatal cardiopulmonary resuscitation or 5-min Apgar score were associated with development of psychotic symptoms during early adolescence. Method. A longitudinal study of 6356 12-year-old adolescents who completed a semi-structured interview for psychotic symptoms in the Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort. Prenatal and perinatal data were obtained from obstetric records and maternal questionnaires completed during pregnancy. Results. The presence of definite psychotic symptoms was associated with maternal infection during pregnancy [adjusted odds ratio (OR) 1.44, 95% confidence interval (CI) 1.11–1.86, p=0.006], maternal diabetes (adjusted OR 3.43, 95% CI 1.14–10.36, p=0.029), need for resuscitation (adjusted OR 1.50, 95% CI 0.97–2.31, p=0.065) and 5-min Apgar score (adjusted OR per unit decrease 1.30, 95% CI 1.12–1.50, p<0.001). None of these associations were mediated by childhood IQ score. Most associations persisted, but were less strong, when including suspected symptoms as part of the outcome. There was no association between PLIKS and gestational age or pre-eclampsia. Conclusions. Adverse events during early development may lead to an increased risk of developing PLIKS. Although the status of PLIKS in relation to clinical disorders such as schizophrenia is not clear, the similarity between these results and findings reported for schizophrenia indicates that future studies of PLIKS may help us to understand how psychotic experiences and clinical disorders develop throughout the life-course

    Infant crying problems and symptoms of sleeping problems predict attachment disorganization at 18 months

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    This longitudinal study examined the associations among infant crying, symptoms of sleeping problems, and attachment while considering the influence of maternal sensitivity and depressive symptoms. One hundred and five healthy full-term infants (42.9% female) were assessed for crying and symptoms of sleeping problems at 3 and 18 months via parental interview. Maternal sensitivity was measured through researcher observation, and attachment was measured at 18 months using the Strange Situation procedure. It was found that infant crying and symptoms of sleeping problems were not linked to the organized patterns of secure or insecure (avoidant versus resistant) attachment. However, when the disorganized attachment was considered, there were direct links found from infant crying and symptoms of sleeping problems at 3 months (β= .22, p< .05) and 18 months (β= .21, p< .05). Thus, crying and symptoms of sleeping problems as early as 3 months may indicate a disruption in the coherence of infants’ relationship to their caretakers

    Associated strangeness production at threshold

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    The associated strangeness dissociation at threshold has been studied at the COSY-11 facility measuring the hyperon - and the K+K- meson pair production. Measurements of the near threshold Lambda and Sigma0 production via the pp -> pK+ Lambda / Sigma0 reaction at COSY-11 have shown that the Lambda / Sigma0 cross section ratio exceeds the value at high excess energies (Q >= 300 MeV) by an order of magnitude. For a better understanding additional data have been taken between 13 MeV and 60 MeV excess energy. The near threshold production of the charged kaon-antikaon pair is related to the discussion about the nature of the scalar states in the 1 GeV/c^2 mass range, i.e. the f0(980) and a0(980). The interpretation as a K anti-K molecule is strongly dependent on the K anti-K interaction which can be studied via the production channel. A first total cross section value on the reaction pp -> ppK+K- at an excess energy of 17 MeV i.e. below the phi production threshold was measured.Comment: 3 pages, 2 figures, Presented at Conference on Quarks and Nuclear Physics (QNP 2002), Julich, Germany, 9-14 Jun 200

    Common mental disorders in young adults born late-preterm

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    Background Results of adulthood mental health of those born late-preterm (34 + 0–36 + 6 weeks + days of gestation) are mixed and based on national registers. We examined if late-preterm birth was associated with a higher risk for common mental disorders in young adulthood when using a diagnostic interview, and if this risk decreased as gestational age increased. Method A total of 800 young adults (mean = 25.3, s.d. = 0.62 years), born 1985–1986, participated in a follow-up of the Arvo Ylppö Longitudinal Study. Common mental disorders (mood, anxiety and substance use disorders) during the past 12 months were defined using the Composite International Diagnostic Interview (Munich version). Gestational age was extracted from hospital birth records and categorized into early-preterm (<34 + 0, n = 37), late-preterm (34 + 0–36 + 6, n = 106), term (37 + 0–41 + 6, n = 617) and post-term (≥42 + 0, n = 40). Results Those born late-preterm and at term were at a similar risk for any common mental disorder [odds ratio (OR) 1.11, 95% confidence interval (CI) 0.67–1.84], for mood (OR 1.11, 95% CI 0.54–2.25), anxiety (OR 1.00, 95% CI 0.40–2.50) and substance use (OR 1.31, 95% CI 0.74–2.32) disorders, and co-morbidity of these disorders (p = 0.38). While the mental disorder risk decreased significantly as gestational age increased, the trend was driven by a higher risk in those born early-preterm. Conclusions Using a cohort born during the advanced neonatal and early childhood care, we found that not all individuals born preterm are at risk for common mental disorders in young adulthood – those born late-preterm are not, while those born early-preterm are at a higher risk. Available resources for prevention and intervention should be targeted towards the preterm group born the earliest
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