MU Neurobehavioral Core Facility: Progressing from Molecules to Behavior

Neuroscience - Vision & Functional Brain Imaging Poster SessionAn important component of modern neuroscience research is the ability to measure systematically and objectively different aspects of behavior. Behavioral analysis is crucial to a strong neuroscience research program because it evaluates the impact of molecular or neurochemical changes on the functioning of the entire organism. Behavioral research can be used to validate the role of a neuroscientist's specific molecular target (e.g., receptor, gene, or enzyme) in a particular behavior (e.g., emotions, learning and memory, or locomotor activity) and subsequently create whole systems that a neuroscientist can use to study a particular pathological state (e.g., depression, drug addiction or obesity). A unique strength of the MU Translational Neuroscience Center is the presence of some “bench” scientists working at the molecular level in pathology, biochemistry and genetics in collaboration with neurobehavioral experts. The Center's modern facilities and trained personnel are available to the MU neuroscience community to help design, conduct and evaluate behavioral research. This will help translate research from the molecular laboratory to the human clinic. This poster will show a summary of the different aspects and tasks we plan to perform at the MU Neurobehavioral Core Facility

Quantification of complementarity in multi-qubit systems

Complementarity was originally introduced as a qualitative concept for the discussion of properties of quantum mechanical objects that are classically incompatible. More recently, complementarity has become a \emph{quantitative} relation between classically incompatible properties, such as visibility of interference fringes and "which-way" information, but also between purely quantum mechanical properties, such as measures of entanglement. We discuss different complementarity relations for systems of 2-, 3-, or \textit{n} qubits. Using nuclear magnetic resonance techniques, we have experimentally verified some of these complementarity relations in a two-qubit system.Comment: 12 pages, 10 figures (A display error about the figures in the previous version

Invalidation of the Kelvin Force in Ferrofluids

Direct and unambiguous experimental evidence for the magnetic force density being of the form $M\nabla B$ in a certain geometry - rather than being the Kelvin force $M\nabla H$ - is provided for the first time. (M is the magnetization, H the field, and B the flux density.)Comment: 4 pages, 4 figure

The importance of ST elevation in V2–4 ECG leads in athletes

Background Early repolarization in the anterior ECG leads (ERV2–4) is considered to be a sign of right ventricular (RV) remodeling, but its etiology and importance are unclear. Methods A total of 243 top-level endurance-trained athletes (ETA; 183 men and 60 women, weekly training hours: 15–20) and 120 leisure-time athletes (LTA; 71 men and 49 women, weekly training hours: 5–6) were investigated. The ERV2–4 sign was evaluated concerning type of sport, gender, transthoracic echocardiographic parameters, and ECG changes, which can indicate elevated RV systolic pressure [left atrium enlargement (LAE), right atrium enlargement (RAE), RV conduction defect (RVcd)]. Results Stroke volume and left ventricular mass were higher in ETAs vs. LTAs in both genders (p < 0.01). Prevalence of the ERV2–4 sign was significantly higher in men than in women [p = 0.000, odds ratio (OR) = 36.4] and in ETAs than in LTAs (p = 0.000). The highest ERV2–4 prevalence appeared in the most highly trained triathlonists and canoe and kayak paddlers (OR = 13.8 and 5.2, respectively). Within the ETA group, the post-exercise LAE, RAE, and RVcd changes developed more frequently in cases with than without ERV2–4 (LAE: men: p < 0.05, females: p < 0.005; RAE: men: p < 0.05, females: p < 0.005; RVcd: N.S.). These post-exercise appearing LAE, RAE, and RVcd are associated with the ERV2–4 sign (OR = 4.0, 3.7, and 3.8, respectively). Conclusions According to these results, ERV2–4 develops mainly in male ETAs due to long-lasting and repeated endurance training. The ERV2–4 sign indicates RV’s adaptation to maintain higher compensatory pulmonary pressure and flow during exercise but its danger regarding malignant arrhythmias is unclear