21 research outputs found

    Demonstration of Mussel Farming in Karnataka: A Success Story

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    Spat settlement along the Karnataka coast occurs during October to November. The mussel fishing season in the region also begins from October. The dense attachment of mussel spats occurs along with adult mussels in the intertidal and subtidal areas, which can be productively utilized for farming, provided a considerable numbers of farmers are involved to establish and maintain the link between mussel farmers and mussel fishers

    Synthesis and antibacterial activity of <i style="mso-bidi-font-style:normal">N</i>-bridged heterocycles derived from aryloxymethyltriazoles

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    1257-1262Reactions of 3-aryloxymethyl-4-amino-5-mercapto-1 ,2,4-triazoles 1 with aromatic carboxylic acids, furoic acid, oxalic acid, monochloroacetic acid and phenacyl bromide furnish various N-bridged heterocycles viz., triazolothiadiazoles, bis-triazolothiadiazoles, triazolothiadiazinones and triazolothiadiazines. The structures of these N-bridged heterocycles are characterized on the basis of elemental analyses, IR, NMR and mass spectral data. Some of these compounds are also subjected to antibacterial screening studies

    Synthesis and antibacterial properties of nitrofuryltriazolothiadiazepines

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    3113-3116Methyl aryl ketones 1 on reaction with 5-nitrofurfuraldehyde 2 give l-aryl-3-(5-nitro-2-furyl)-2-propen-1-ones 3 which on bromination affords 2,3-dibromo-1-aryl-3-(5-nitro-2-furyl )-2-propen-1-ones 4. Debromination of 4 by triethylamine in benzene results in 1-aryl-3-(5-nitro-2-furyl)-2-propen-1-ones 5 which on condensation with 3-substituted-4-amino-5-mercapto-1,2,4-triazole 6 furnishes Michael adducts 7. The Michael adduct 7 undergoes cyclization in conc. sulphuric acid to give 3-aryloxymethyl-6-aryl-8-(5-nitro-2-furyl)-1,2,4-triazolothiadiazepines 8. Antibacterial activity of 7 and 8 has been reported

    Zinc (ii) complexes as antimicrobial and DNA cleaving agents: synthesis and spectral characterization

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    The Zinc (II) complexes of 4(3H)-quinazolinone derived Schiff base ligand were prepared. Both free ligand and its Zinc (II) complexes were characterized by elemental analyses, spectral methods (IR, 1HNMR, MS and UV–Vis), molar conductance measurements and thermal studies. The bidentate ligand coordinated to the Zinc (II) ion through the lactum oxygen and the azomethine nitrogen of the ligand. All of the compounds were investigated for their antimicrobial activities against the Gram-positive and Gram-negative bacteria and fungi. The nuclease activity was performed using supercoiled pUC19 plasmid DNA

    Synthesis, characterization and biological studies of some triazolothiadiazines and triazolothiadiazoles containing 6-chloropyridin-3-yl methyl moiety

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    2071-20764-Amino-5-(6-chloropyridin-3-yl methyl)-4H-1,2,4-triazole-3-thiol has been synthesized and was converted into 3-(6-chloropyridin-3-yl methyl)-6-(4-substituted-phenyl)-7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines and (6-chloropyridin-3-yl­methyl)-6-(4-substituted-phenyl)-7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles. The newly synthesized compounds are characterized on the basis of elemental analysis, IR, 1H NMR and mass spectral data. Some of the compounds are screened for their antibacterial and insecticidal activities

    Synthesis and characterization of 1,3,4-thiadiazole and 1,3,4-oxadiazole derivatives containing 2-chloropyridin-5-yl-methyl moiety

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    2170-2174Reaction of 2-chloropyridine-5-acetic acid hydrazide 1 with aroyl isothiocyanates 2a-e yields 4-aroyl -1-(2-chloropyridine-5-acetyl)thiosemicarbazides 3a-e. The cyaclization of 3a-e with conc. sulphuric acid and with iodine in the presence of potassium iodide affords 2-chloro-5-(5-aroylamino-1,3,4-thidiazol -2-yl-methyl)pyridines 4a-e and 2-chloro-5-(5-aroylamino-1 ,3,4-oxadiazol-2-yl-methyl) pyridines 5a-e respectively

    Synthesis and Characterization of 1,3,4-Thiadiazole and 1,3,4-Oxadiazole Derivatives Containing 2-Chloropyridin-5-yl-methyl Moiety.

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    2170-2174Reaction of 2-chloropyridine-5-acetic acid hydrazide 1 with aroyl isothiocyanates 2a-e yields 4-aroyl -1-(2-chloropyridine-5-acetyl)thiosemicarbazides 3a-e. The cyaclization of 3a-e with conc. sulphuric acid and with iodine in the presence of potassium iodide affords 2-chloro-5-(5-aroylamino-1,3,4-thidiazol -2-yl-methyl)pyridines 4a-e and 2-chloro-5-(5-aroylamino-1 ,3,4-oxadiazol-2-yl-methyl) pyridines 5a-e respectively
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