VirtuWind: Virtual and Programmable Industrial Network Prototype Deployed in Operational Wind Park

With anticipated exponential growth of connected devices, future industrial networks require an open solutions architecture facilitated by standards and a strong ecosystem.VirtuWind aims to develop and demonstrate an SDN and NFV ecosystem, based on an open, modular and secure framework.A prototype of the framework for intra-domain and inter-domain scenarios will be showcased in real wind parks,as a representative use case of industrial networks. Validate the economic viability of the demonstrated solution is paramount for VirtuWind. This paper details this vision and explains steps forward

A Reactive Security Framework for Operational Wind Parks Using Service Function Chaining

The innovative application of 5G core technologies, namely Software Defined Networking (SDN) and Network Function Virtualization (NFV), can help reduce capital and operational expenditures in industrial networks. Nevertheless, SDN expands the attack surface of the communication infrastructure, thus necessitating the introduction of additional security mechanisms. A wind park is a good example of an industrial application relying on a network with strict performance, security, and reliability requirements, and was chosen as a representative example of industrial systems. This work highlights the benefit of leveraging the flexibility of SDN/NFV-enabled networks to deploy enhanced, reactive security mechanisms for the protection of the industrial network, via the use of Service Function Chaining. Moreover, a proof of concept implementation of the reactive security framework for an industrial-grade wind park network is presented. The framework is equipped with SDN and SCADA honeypots, modelled on (and deployable to) an actual, operating wind park, allowing continuous monitoring of the industrial network and detailed analysis of potential attacks, thus isolating attackers and enabling the assessment of their level of sophistication

Participatory Modeling for Analyzing Interactions Between High‐Priority Sustainable Development Goals to Promote Local Sustainability

Achieving the Sustainable Development Goals (SDGs) is challenging given the complex interactions between different SDGs and their spillover effects. We developed a system dynamics model—the Local Environmental and Socio-Economic Model (LESEM)—to analyze and quantify context-based SDG interactions at the local scale using a participatory model co-design process with local stakeholders. The LESEM was developed for the Goulburn-Murray Irrigation District in Victoria, Australia, to assist policymakers in analyzing local issues with a more integrated and holistic approach to sustainable development at the local scale. The process of participatory systems dynamics modeling facilitates integrated and strategic decision-making and can help local policymakers identify and quantify potential trade-offs and synergies that benefit multiple SDGs, which eventually leads local communities toward sustainability. We present an illustrative application of the model that quantifies SDG interactions across four high-priority SDGs, namely clean water and sanitation (SDG 6), zero hunger (SDG 2), economic growth (SDG 8), and life on land (SDG 15). We illustrate the use of the model in assessing key SDG indicator trajectories under a business-as-usual (BAU) scenario from 2010 to 2050. Under the BAU, agri-food production increased despite a decline in water resource availability, with gains driven by intensification and increased agricultural productivity. This boosted local prosperity and reduced the amount of agricultural land required to meet future agri-food demand, thereby reducing pressures on terrestrial ecosystems and creating the space for ecological restoration and carbon storage in soils and biomass. However, agricultural intensification impacted water quality through increases in algal blooms and river salinity

Differential Proteome Analysis of Bone Marrow Mesenchymal Stem Cells from Adolescent Idiopathic Scoliosis Patients

Adolescent idiopathic scoliosis (AIS) is a complex three-dimensional deformity of the spine. The cause and pathogenesis of scoliosis and the accompanying generalized osteopenia remain unclear despite decades of extensive research. In this study, we utilized two-dimensional fluorescence difference gel electrophoresis (2D-DIGE) coupled with mass spectrometry (MS) to analyze the differential proteome of bone marrow mesenchymal stem cells (BM-MSCs) from AIS patients. In total, 41 significantly altered protein spots were detected, of which 34 spots were identified by MALDI-TOF/TOF analysis and found to represent 25 distinct gene products. Among these proteins, five related to bone growth and development, including pyruvate kinase M2, annexin A2, heat shock 27 kDa protein, γ-actin, and β-actin, were found to be dysregulated and therefore selected for further validation by Western blot analysis. At the protein level, our results supported the previous hypothesis that decreased osteogenic differentiation ability of MSCs is one of the mechanisms leading to osteopenia in AIS. In summary, we analyzed the differential BM-MSCs proteome of AIS patients for the first time, which may help to elucidate the underlying molecular mechanisms of bone loss in AIS and also increase understanding of the etiology and pathogenesis of AIS

Challenges in assessing and managing multi-hazard risks: A European stakeholders perspective

The latest evidence suggests that multi-hazards and their interrelationships (e.g., triggering, compound, and consecutive hazards) are becoming more frequent across Europe, underlying a need for resilience building by moving from single-hazard-focused to multi-hazard risk assessment and management. Although significant advancements were made in our understanding of these events, mainstream practice is still focused on risks due to single hazards (e.g., flooding, earthquakes, droughts), with a limited understanding of the stakeholder needs on the ground. To overcome this limitation, this paper sets out to understand the challenges for moving towards multi-hazard risk management through the perspective of European stakeholders. Based on five workshops across different European pilots (Danube Region, Veneto Region, Scandinavia, North Sea, and Canary Islands) and an expert workshop, we identify five prime challenges: i) governance, ii) knowledge of multi-hazards and multi-risks, iii) existing approaches to disaster risk management, iv) translation of science to policy and practice, and v) lack of data. These challenges are inherently linked and cannot be tackled in isolation with path dependency posing a significant hurdle in transitioning from single- to multi-hazard risk management. Going forward, we identify promising approaches for overcoming some of the challenges, including emerging approaches for multi-hazard characterisation, a common understanding of terminology, and a comprehensive framework for guiding multi-hazard risk assessment and management. We argue for a need to think beyond natural hazards and include other threats in creating a comprehensive overview of multi-hazard risks, as well as promoting thinking of multi-hazard risk reduction in the context of larger development goals