22,606 research outputs found
Parallel matrix inversion techniques
In this paper, we present techniques for inverting sparse, symmetric and positive definite matrices on parallel and distributed computers. We propose two algorithms, one for SIMD implementation and the other for MIMD implementation. These algorithms are modified versions of Gaussian elimination and they take into account the sparseness of the matrix. Our algorithms perform better than the general parallel Gaussian elimination algorithm. In order to demonstrate the usefulness of our technique, we implemented the snake problem using our sparse matrix algorithm. Our studies reveal that the proposed sparse matrix inversion algorithm significantly reduces the time taken for obtaining the solution of the snake problem. In this paper, we present the results of our experimental work
Dielectric Breakdown Strength of Polyethylene Nanocomposites
The term “nanometric dielectrics” or simply “nanodielectrics” was introduced in 1994 when Lewis [1] anticipated the potential property changes that would benefit electrical insulation due to nano-sized inclusion. Such materials, containing homogenous dispersion of small amount (normally less than 10wt%) of nanoparticles (with at least one dimension in nanometre range) in host matrix, are of specific dielectric interest. Although much effort has been put forth to investigate the potential dielectric benefit of such newly emerging materials, many uncertainties remain unanswered, and much remains to be explored [2]. Current experimental work is to investigate the preparation of nanodielectrics via solution blending approach. Polyethylene blend composed of 20wt% of high density polyethylene (HDPE) in low density polyethylene (LDPE) is proposed as the base polymer, with varying content of nanosilica (between 0wt% and 10wt%) as the fillers. Although expensive, solution blending method, when compared with melt compounding method, is expected to provide better dispersion of nanoparticles in polymers, thus providing qualitative data in understanding the behaviour of nanodielectrics [3]. Upon successful preparation of polyethylene nanocomposites, breakdown strength based on ASTM Standard D149-87 is to be conducted to determine the feasibility of such dielectric materials in engineering point of view. Figure 1 illustrates the schematic diagram of the breakdown test configuration. The samples are placed between two 6.3mm diameter steel ball bearings immersed in silicone fluid. AC voltage at a preset ramp rate will be applied until the samples fail and the values of breakdown voltages will be recorded and analysed using two-parameter Weibull distribution. Based upon top-down research approach, the underlying physics and chemistry associated with dielectric property changes will then be explored
Evaluation of present thermal barrier coatings for potential service in electric utility gas turbines
The resistance of present-day thermal barrier coatings to combustion gases found in electric utility turbines was assessed. The plasma sprayed coatings, both duplex and graded types, were primarily zirconia-based, although a calcium silicate was also evaluated. Both atmospheric burner rig tests and high pressure tests (135 psig) showed that several present-day thermal barrier coatings have a high potential for service in gas turbines burning the relatively clean GT No. 2 fuel. However, coating improvements are needed for use in turbines burning lower grade fuel such as residual oil. The duplex ZrO2.8Y2O3/NiCrA1Y coating was ranked highest and selected for near-term field testing, with Ca2SiO4/NiCrA1Y ranked second. Graded coatings show potential for corrosive turbine operating conditions and warrant further development. The coating degradation mechanisms for each coating system subjected to the various environmental conditions are also described
Ti and V layers retard interaction between Al films and polycrystalline Si
Fine-grained polycrystalline Si (poly Si) in contact with Al films recrystallizes at temperatures well below the Si-Al eutectic (577 °C). We show that this interaction can be deferred or suppressed by placing a buffer layer of Ti or V between the Al film and the poly Si. During annealing, Ti or V form TiAl3 or Val3 at the buffer-layer–Al-film interface, but do not react with the poly Si so that the integrity of the poly Si is preserved as long as some unreacted Ti or V remains. The reaction between the Ti or V layer and the Al film is transport limited ([proportional]t^1/2) and characterized by the diffusion constants 1.5×10^15 exp(–1.8eV/kT) Å^2/sec or 8.4×10^12 exp(–1.7eV/kT) Å^2/sec, respectively
A Study of Factors Influencing Green IT Practices, Buying and Subscription Behaviours of Computer and Mobile Devices, and Streaming Services
The pressure of environmental sustainability and the introduction of strict transnational and local environment laws, regulations and targets have catalysed the emergency of Green IT. On individual level, Green IT can be achieved through environmentally responsible behaviour to purchase, use and disposal of products and services without damaging the environment. This research aims to investigate the Green IT behaviour of young consumers including their day-to-day Green IT practices, buying behaviour of mobile and computer devices and subscription behaviour of streaming services. The findings show that: 1) Understanding of Green IT practices (specific knowledge) has a positive influence on PBC, 2) Consumer’s PBC has a positive influence on Green IT behaviour and 3) The communication strategy has a positive influence on PBC. Research results also show that young consumers’ buying and subscribing decision are strongly influenced by factors such as appearance, specification, features, content and price than Green IT factors.
Available at: https://aisel.aisnet.org/pajais/vol11/iss1/4
Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections.
BACKGROUND: Monitoring resistance phenotypes for Plasmodium falciparum, using in vitro growth assays, and relating findings to parasite genotype has proved particularly challenging for the study of resistance to artemisinins.
METHODS: Plasmodium falciparum isolates cultured from 28 returning travellers diagnosed with malaria were assessed for sensitivity to artemisinin, artemether, dihydroartemisinin and artesunate and findings related to mutations in pfatp6 and pfmdr1.
RESULTS: Resistance to artemether in vitro was significantly associated with a pfatp6 haplotype encoding two amino acid substitutions (pfatp6 A623E and S769N; (mean IC50 (95% CI) values of 8.2 (5.7 - 10.7) for A623/S769 versus 623E/769 N 13.5 (9.8 - 17.3) nM with a mean increase of 65%; p = 0.012). Increased copy number of pfmdr1 was not itself associated with increased IC50 values for artemether, but when interactions between the pfatp6 haplotype and increased copy number of pfmdr1 were examined together, a highly significant association was noted with IC50 values for artemether (mean IC50 (95% CI) values of 8.7 (5.9 - 11.6) versus 16.3 (10.7 - 21.8) nM with a mean increase of 87%; p = 0.0068). Previously described SNPs in pfmdr1 are also associated with differences in sensitivity to some artemisinins.
CONCLUSIONS: These findings were further explored in molecular modelling experiments that suggest mutations in pfatp6 are unlikely to affect differential binding of artemisinins at their proposed site, whereas there may be differences in such binding associated with mutations in pfmdr1. Implications for a hypothesis that artemisinin resistance may be exacerbated by interactions between PfATP6 and PfMDR1 and for epidemiological studies to monitor emerging resistance are discussed
Structural evaluation of concrete expanded polystyrene sandwich panels for slab applications
Sandwich panels are being extensively and increasingly used in building construction because they are light in weight, energy efficient, aesthetically attractive and can be easily handled and erected. This paper presents a structural evaluation of Concrete-Expanded Polystyrene (CEPS) sandwich panels for slab applications using finite element modeling approach. CEPS panels are made of expanded polystyrene foam sandwiched between concrete skins. The use of foam in the middle of sandwich panel reduces the weight of the structure and also acts as insulation against thermal, acoustics and vibration. Applying reinforced concrete skin to both sides of panel takes the advantages of the sandwich concept where the reinforced concrete skins take compressive and tensile loads resulting in higher stiffness and strength and the core transfers shear loads between the faces. This research uses structural software Strand7, which is based on finite element method, to predict the load deformation behaviour of the CEPS sandwich slab panels. Non linear static analysis was used in the numerical investigations. Predicted results were compared with the existing experimental results to validate the numerical approach used
A system to enrich for primitive streak-derivatives, definitive endoderm and mesoderm, from pluripotent cells in culture
Two lineages of endoderm develop during mammalian embryogenesis, the primitive endoderm in the pre-implantation blastocyst and the definitive endoderm at gastrulation. This complexity of endoderm cell populations is mirrored during pluripotent cell differentiation in vitro and has hindered the identification and purification of the definitive endoderm for use as a substrate for further differentiation. The aggregation and differentiation of early primitive ectoderm-like (EPL) cells, resulting in the formation of EPL-cell derived embryoid bodies (EPLEBs), is a model of gastrulation that progresses through the sequential formation of primitive streak-like intermediates to nascent mesoderm and more differentiated mesoderm populations. EPL cell-derived EBs have been further analysed for the formation of definitive endoderm by detailed morphological studies, gene expression and a protein uptake assay. In comparison to embryoid bodies derived from ES cells, which form primitive and definitive endoderm, the endoderm compartment of embryoid bodies formed from EPL cells was comprised almost exclusively of definitive endoderm. Definitive endoderm was defined as a population of squamous cells that expressed Sox17, CXCR4 and Trh, which formed without the prior formation of primitive endoderm and was unable to endocytose horseradish peroxidase from the medium. Definitive endoderm formed in EPLEBs provides a substrate for further differentiation into specific endoderm lineages; these lineages can be used as research tools for understanding the mechanisms controlling lineage establishment and the nature of the transient intermediates formed. The similarity between mouse EPL cells and human ES cells suggests EPLEBs can be used as a model system for the development of technologies to enrich for the formation of human ES cell-derived definitive endoderm in the future.Sveltana Vassilieva, Hweee Ngee Goh, Kevin X. Lau, James N. Hughes, Mary Familari, Peter D. Rathjen and Joy Rathje
- …