Systematic environmental influences and variances due to direct and maternal effects and trends for yearling weight in cattle

Pedigree yearling records from 1021 local Tuli calves born at Matopos Research Station were analyzed for non genetic factors, genetic parameers and trends on the yearling weight. It was found that sre year of brth, sex of calf age of dam had sgnfcant effect (p < 0.01) on a growthtrait. The inconsistency of literature estimates indicated the importance o estmation of environmental factors that affect yearling weight within specific experimental herds and environment. Model incorporating both direct and maternal additive genetic effect, covariance and correlations of direct-maternal and permanent environmental maternal effects was adopted for thestudy Directand maternal heritabity estmates of 0.18 ± 0.001 and 0.04 ± 0001 were observed, respectvely. Direct-maternal genetic correlaton was low andposive, 0.07± 0.012. The regression of average direct breeding values on year was almost zero and the regression of average maternal breeding values on year 0.03 kg/yr. Correction of environmental effects was necessary to increase accuracy for selection of yearling weight in local Tuli cattle. Maternal genetic effects should be included in a model of covariance components estimation at 12 months of age.Keywords: Non genetic, Direct, Maternal trends, Yearling weight, Growth traits, Tuli cattl

The Cost of Health-related Brain Drain to the WHO African Region

The African Region continues to experience loss of a sizeable number of highly skilled health professionals (physicians, nurses, dentists and pharmacists) to Australia, North America and European Union. Past attempts to estimate cost of migration were limited to education cost only and did not include the lost returns from investment. The objective of this study was to estimate the social cost of emigration of doctors and nurses from the African Region to the developed countries. The cost information used in this study was obtained from one nonprofit primary and secondary school and one public university in Kenya. The cost estimates represent unsubsidized cost. The loss incurred by African countries through emigration is obtained by compounding the cost of educating a medical doctor and a nurse over the period between the age of emigration and the retirement age in recipient countries. The main findings were as follows: total cost of educating a single medical doctor from primary school to university is US$65,997; for every doctor that emigrates, a country loses about US$1,854,677 returns from investment; total cost of educating one nurse from primary school to college of health sciences is US$43,180; for every nurse that emigrates, a country loses about US$1,213,463 returns from investment. Developed countries continue to deprive African countries of billions of dollars worth of invaluable investments embodied in their human resources. If the current trend of poaching of scarce human resources for health (and other professionals) from African countries is not curtailed, the chances of achieving the Millennium Development Goals would remain dismal. Such continued plunder of investments embodied in human resources contributes to further underdevelopment of Africa and to keeping majority of her people in the vicious circle of poverty. Therefore, both developed and developing countries need to urgently develop and implement strategies for addressing this issue

Protecting migratory farmers in rural Tanzania using eave ribbons treated with the spatial mosquito repellent, transfluthrin.

BACKGROUND: Many subsistence farmers in rural southeastern Tanzania regularly relocate to distant farms in river valleys to tend to crops for several weeks or months each year. While there, they live in makeshift semi-open structures, usually far from organized health systems and where insecticide-treated nets (ITNs) do not provide adequate protection. This study evaluated the potential of a recently developed technology, eave ribbons treated with the spatial repellent transfluthrin, for protecting migratory rice farmers in rural southeastern Tanzania against indoor-biting and outdoor-biting mosquitoes. METHODS: In the first test, eave ribbons (0.1 m × 24 m each) treated with 1.5% transfluthrin solution were compared to untreated ribbons in 24 randomly selected huts in three migratory communities over 48 nights. Host-seeking mosquitoes indoors and outdoors were monitored nightly (18.00-07.00 h) using CDC light traps and CO2-baited BG malaria traps, respectively. The second test compared efficacies of eave ribbons treated with 1.5% or 2.5% transfluthrin in 12 huts over 21 nights. Finally, 286 farmers were interviewed to assess perceptions about eave ribbons, and their willingness to pay for them. RESULTS: In the two experiments, when treated eave ribbons were applied, the reduction in indoor densities ranged from 56 to 77% for Anopheles arabiensis, 36 to 60% for Anopheles funestus, 72 to 84% for Culex, and 80 to 98% for Mansonia compared to untreated ribbons. Reduction in outdoor densities was 38 to 77% against An. arabiensis, 36 to 64% against An. funestus, 63 to 88% against Culex, and 47 to 98% against Mansonia. There was no difference in protection between the two transfluthrin doses. In the survey, 58% of participants perceived the ribbons to be effective in reducing mosquito bites. Ninety per cent were willing to pay for the ribbons, the majority of whom were willing to pay but less than US$2.17 (5000 TZS), one-third of the current prototype cost. CONCLUSIONS: Transfluthrin-treated eave ribbons can protect migratory rice farmers, living in semi-open makeshift houses in remote farms, against indoor-biting and outdoor-biting mosquitoes. The technology is acceptable to users and could potentially complement ITNs. Further studies should investigate durability and epidemiological impact of eave ribbons, and the opportunities for improving affordability to users

Linking human behaviours and malaria vector biting risk in south-eastern Tanzania

To accelerate malaria elimination in areas where core interventions such as insecticide-treated nets (ITNs) are already widely used, it is crucial to consider additional factors associated with persistent transmission. Qualitative data on human behaviours and perceptions regarding malaria risk was triangulated with quantitative data on Anopheles mosquito bites occurring indoors and outdoors in south-eastern Tanzania communities where ITNS are already used but lower level malaria transmission persists. Each night (18:00h-07:00h), trained residents recorded human activities indoors, in peri-domestic outdoor areas, and in communal gatherings. Host-seeking mosquitoes were repeatedly collected indoors and outdoors hourly, using miniaturized exposure-free double net traps (DN-Mini) occupied by volunteers. In-depth interviews were conducted with household representatives to explore perceptions on persistent malaria and its control. Higher proportions of people stayed outdoors than indoors in early-evening and early-morning hours, resulting in higher exposures outdoors than indoors during these times. However, exposure during late-night hours (22:00h-05:00h) occurred mostly indoors. Some of the popular activities that kept people outdoors included cooking, eating, relaxing and playing. All households had at least one bed net, and 83.9% of people had access to ITNs. Average ITN use was 96.3%, preventing most indoor exposure. Participants recorgnized the importance of ITNs but also noted that the nets were not perfect. No complementary interventions were reported being used widely. Most people believed transmission happens after midnight. We conclude that insecticide-treated nets, where properly used, can still prevent most indoor exposures, but significant risk continues unabated before bedtime, outdoors and at communal gatherings. Such exposure is greatest for rural and low-income households. There is therefore an urgent need for complementary interventions, particularly those targeting outdoor-biting and are applicable for all people including the marginalised populations such as migratory farmers and fishermen. Besides, the differences in community understanding of ongoing transmission, and feedback on imperfections of ITNs should be considered when updating malaria-related communication and interventions

Sex Specific Genetic and Environmental Trends in Birth Weight of Indigenous Nguni Conservation Cattle Herd of Zimbabwe

Best linear unbiased predictors (BLUP) of breeding values for additive direct and additive maternal genetic effects were estimated from pedigree birth weight (BWT) records of 4272 indigenous Nguni cattle of Zimbabwe, born between 1988 and 1997.&nbsp; Data was partitioned according to sex and breeding values for direct additive and maternal additive and were estimated using an univariate animal models. Estimates of sex specific genetic trends for direct and maternal effects were obtained by averaging corresponding breeding values for partitioned data of animals born in a given year, and regressing these averages on year of birth. The regression of average direct breeding values on year for males and females were &ndash;0.0236 and &ndash;0.1263 kg/yr, respectively, and the regression of average maternal breeding values on year for birth were -0.0355 and &ndash;0.0173 kg/yr for males and females respectively. A positive environmental trend was observed for both sexes but was non-significant. Estimation of sex specific variance components had no significant influence on the direction and magnitude of genetic trends indicating of homogeneity of variance by sex for birth weight in this population. Keywords: Breeding values, maternal genetic effects, birth weight, Nguni cattle, Zimbabw

Tutorials to support learning: Experiences of nursing students in a competency-based nursing programme

No Abstract