The Effect of Selective Hypothermia on Stroke Volume

Hypothermia is a well-established neuroprotectant. Selective hypothermia to the ischemic area may eliminate side effects while improving induction time. We studied the effect of selective hypothermia on stroke volumes in adult domestic swine. Under general anesthesia, one MCA was occluded transcranially for 3 hours followed by 3 hours of reperfusion. In half the animals, hypothermia was induced during reperfusion via a dual-lumen balloon occlusion catheter placed in the carotid ipsilateral to the ischemic region. Following reperfusion, the animals were sacrificed. Brain MRI and histology were evaluated blinded to the intervention. In a series of animals, the mean temperature achieved was 26.5C. Mean time from start of perfusion to moderate hypothermia (\u3c 30 C) was 25.4 minutes. Mean stroke volumes were reduced by 38.4-44.2% in the hypothermia group (p=0.292). Selective moderate hypothermia can be rapidly induced using endovascular technology. A promising reduction in stroke volumes is seen. Further study is warranted

The interaction of spaced retrieval practice and element interactivity.

Our study investigates the interaction of retrieval practice and element interactivity. Spaced practice is the process of breaking up the retrieval of information into smaller chunks across a longer period of time as opposed to learning everything in one time block. Retrieval practice is the process of testing yourself on previously learned material. Spaced retrieval practice is the merger of these two ideas. This style of learning is well-suited for learning many items that must be retained indefinitely (Lyle et al., 2019). Element interactivity describes the amount of learned items (elements) that are interrelated and must be processed together in working memory to be learned effectively. We utilized a within-subjects crossing of spaced retrieval practice and element interactivity in a psychology course for undergraduate participants. This study focused on memorization of neuroanatomy structures across a semester. Practice consisted of neuroanatomy labs in which structures were reviewed six times total across three labs. After a two-month delay, assessment consisted of a final in which participants attempted to label each structure from the neuroanatomy labs. Results suggested that spaced retrieval practice was more effective with more element interactivity. Given these findings, future research should focus on further clarifying the efficacy of spaced retrieval practice when affected by other common factors in educational settings. This research is vital for further developing a nuanced and effective curriculum at all educational levels

Measurement of D^\pm Production in Deep Inelastic ep Scattering with the ZEUS Detector at HERA

Charm production in deep inelastic ep scattering was measured with the ZEUS detector using an integrated luminosity of 354 pb^{-1}. Charm quarks were identified by reconstructing D^{+} mesons in the D^{+} -\u3e K^{-} pi^{+} pi^{+} decay channel. Lifetime information was used to reduce combinatorial background substantially. Differential cross sections were measured in the kinematic region 5 \u3c Q^{2} \u3c 1000 GeV^{2}, 0.02 \u3c y \u3c 0.7, 1.5 \u3c p_{T}(D^{+}) \u3c 15 GeV and |eta(D^{+})| \u3c 1.6, where Q^{2} is the photon virtuality, y is the inelasticity, and p_{T}(D^{+}) and eta(D^{+}) are the transverse momentum and the pseudorapidity of the D^{+} meson, respectively. Next-to-leading-order QCD predictions are compared to the data. The charm contribution, F_{2}^{cc}, to the proton structure-function F_{2} was extracted

Measurement of D^*\pm Production in Deep Inelastic Scattering at HERA

The production of D∗± mesons in deep inelastic ep scattering has been measured for exchanged photon virtualities 5 \u3c Q2\u3c1000GeV2, using an integrated luminosity of 363 pb−1 with the ZEUS detector at HERA. Differential cross sectionshave been measured and compared to next-to-leading-order QC D calculations. The cross-sections are used to extract the charm contribution to the protonstructure functions, expressed in terms of the reduced charm cro ss section, σc̄cred. Theoretical calculations based on fits to inclusive HERA data are compared to the results

Combination and QCD Analysis of Charm Production Cross Section Measurements in Deep-Inelastic ep Scattering at HERA

Measurements of open charm production cross sections in deep-inelastic ep scattering at HERA from the H1 and ZEUS Collaborations are combined. Reduced cross sections sigma_red^{c\bar{c}} for charm production are obtained in the kinematic range of photon virtuality 2.

Effects of daily SKF 38393, quinpirole, and SCH 23390 treatments on locomotor activity and subsequent sensitivity to apomorphine

An article written by Bruce Mattingly and published in Spring 1993 issue of Psychopharmacology, pages 320-326

Neurochemical Correlates of Behavior Sensitization Following Repeated Apomorphine Treatment: Assessment of the Role of D1 Dopamine Receptor Stimulation

An article written by Bruce A. Mattingly and published in the Spring 1993 issue of Synapse

Repeated Quinpirole Treatment: Locomotor Activity, Dopamine Synthesis and Effects of Selective Dopamine Antagonists

A report submitted by Bruce A. Mattingly the Research and Creative Productions Committee on the repeated treatment with the non-selective dopamine agonist apomorphine results in behavioral sensitization and enhanced dopamine synthesis in dopamine projection fields